Aliases for SSPN Gene
External Ids for SSPN Gene
Previous HGNC Symbols for SSPN Gene
Previous GeneCards Identifiers for SSPN Gene
This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
GeneCards Summary for SSPN Gene
SSPN (Sarcospan) is a Protein Coding gene. Diseases associated with SSPN include Adrenal Carcinoma and Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2C. Among its related pathways are Muscular Dystrophies and Dystrophin-Glycoprotein Complex.
UniProtKB/Swiss-Prot Summary for SSPN Gene
Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.