Aliases for SRSF9 Gene
External Ids for SRSF9 Gene
Previous HGNC Symbols for SRSF9 Gene
Previous GeneCards Identifiers for SRSF9 Gene
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. [provided by RefSeq, Sep 2010]
GeneCards Summary for SRSF9 Gene
SRSF9 (Serine And Arginine Rich Splicing Factor 9) is a Protein Coding gene. Diseases associated with SRSF9 include Aromatic L-Amino Acid Decarboxylase Deficiency and Spinocerebellar Ataxia 31. Among its related pathways are Cleavage of Growing Transcript in the Termination Region and Transport of Mature Transcript to Cytoplasm. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is SRSF1.
UniProtKB/Swiss-Prot Summary for SRSF9 Gene
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.