The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different ... See more...

Aliases for SRSF2 Gene

Aliases for SRSF2 Gene

  • Serine And Arginine Rich Splicing Factor 2 2 3 5
  • Splicing Factor, Arginine/Serine-Rich 2 2 3 4
  • Serine/Arginine-Rich Splicing Factor 2 2 3 4
  • SC-35 2 3 4
  • Splicing Component, 35 KDa 3 4
  • SR Splicing Factor 2 2 3
  • Splicing Factor SC35 3 4
  • SFRS2A 2 3
  • PR264 2 3
  • SFRS2 3 4
  • SC35 2 3
  • Protein PR264 4
  • SRp30b 3
  • SRSF2 5

External Ids for SRSF2 Gene

Previous HGNC Symbols for SRSF2 Gene

  • SFRS2

Previous GeneCards Identifiers for SRSF2 Gene

  • GC17M074731
  • GC17M070157

Summaries for SRSF2 Gene

Entrez Gene Summary for SRSF2 Gene

  • The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]

CIViC Summary for SRSF2 Gene

GeneCards Summary for SRSF2 Gene

SRSF2 (Serine And Arginine Rich Splicing Factor 2) is a Protein Coding gene. Diseases associated with SRSF2 include Aggressive Systemic Mastocytosis and Systemic Mastocytosis With Associated Hematologic Neoplasm. Among its related pathways are Cleavage of Growing Transcript in the Termination Region and mRNA Splicing - Minor Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is SRSF8.

UniProtKB/Swiss-Prot Summary for SRSF2 Gene

  • Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.

Gene Wiki entry for SRSF2 Gene

Additional gene information for SRSF2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SRSF2 Gene

Genomics for SRSF2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SRSF2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J076734 Promoter/Enhancer 2.6 UCNEbase EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 740.9 +0.2 152 7.8 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A PRDM10 ZNF629 REST TFE3 ZNF512 SRSF2 MFSD11 NONHSAG022835.2 MN297510 MIR636 lnc-JMJD6-1 UNK ENSG00000267342 TRIM65 ENSG00000266980
GH17J075776 Promoter/Enhancer 2.8 UCNEbase EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 106.8 +955.5 955521 11.6 RNF2 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A CTCF ZBTB33 ARID3A TEAD4 UNK SRSF2 NUP85 NT5C ENSG00000267342 TRIM65 ENSG00000266980 GGA3 ENSG00000267546 METTL23
GH17J077233 Enhancer 1.6 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 165.3 -497.4 -497424 3.3 ZNF221 CREB1 ZBTB33 ATF7 PRDM10 ZNF629 LEF1 ZNF692 ZNF174 BACH1 SRSF2 METTL23 ENSG00000267546 SEPTIN9 TNRC6C PRPSAP1 SNHG20 MFSD11 RNU4-47P ENSG00000267543
GH17J076380 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 79.9 +353.5 353450 7.3 RNF2 HNRNPL GATAD2A CTCF PRDM10 ZNF629 TFE3 SOX13 IKZF1 NFKBIZ SPHK1 PRPSAP1 UNK SRSF2 ENSG00000267342 ENSG00000266980 TRIM65 ENSG00000267546 SAP30BP METTL23
GH17J076258 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 68.3 +469.4 469436 19.6 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 ZNF629 TFE3 LEF1 UBALD2 UNK ENSG00000267342 SRSF2 TRIM65 ENSG00000267546 ENSG00000266980 EXOC7 RNF157 PRPSAP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SRSF2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SRSF2

Genomic Locations for SRSF2 Gene

Genomic Locations for SRSF2 Gene
chr17:76,734,115-76,737,411
(GRCh38/hg38)
Size:
3,297 bases
Orientation:
Minus strand
chr17:74,730,197-74,733,493
(GRCh37/hg19)
Size:
3,297 bases
Orientation:
Minus strand

Genomic View for SRSF2 Gene

Genes around SRSF2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SRSF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SRSF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SRSF2 Gene

Proteins for SRSF2 Gene

  • Protein details for SRSF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q01130-SRSF2_HUMAN
    Recommended name:
    Serine/arginine-rich splicing factor 2
    Protein Accession:
    Q01130
    Secondary Accessions:
    • B3KWD5
    • B4DN89
    • H0YG49

    Protein attributes for SRSF2 Gene

    Size:
    221 amino acids
    Molecular mass:
    25476 Da
    Quaternary structure:
    • Interacts with BRDT (By similarity). In vitro, self-associates and binds SRSF1/SFRS1 (ASF/SF2), SNRNP70 and U2AF1 but not U2AF2. Binds SREK1/SFRS12. Interacts with CCNL1 and CCNL2. Interacts with SCAF11. Interacts with ZRSR2/U2AF1-RS2. Interacts with CCDC55 (via C-terminus).

    Three dimensional structures from OCA and Proteopedia for SRSF2 Gene

    Alternative splice isoforms for SRSF2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SRSF2 Gene

Post-translational modifications for SRSF2 Gene

  • Extensively phosphorylated on serine residues in the RS domain. Phosphorylated by SRPK2 and this causes its redistribution from the nuclear speckle to nucleoplasm and controls cell fate decision in response to cisplatin treatment. KAT5/TIP60 inhibits its phosphorylation by preventing SRPK2 nuclear translocation.
  • Acetylation on Lys-52 by KAT5/TIP60 promotes its proteasomal degradation. This effect is counterbalanced by HDAC6, which positively controls SRSF2 protein level by deacetylating it and preventing its proteasomal degradation.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for SRSF2

No data available for DME Specific Peptides for SRSF2 Gene

Domains & Families for SRSF2 Gene

Gene Families for SRSF2 Gene

Protein Domains for SRSF2 Gene

InterPro:
Blocks:
  • RNA-binding region RNP-1 (RNA recognition motif)
ProtoNet:

Suggested Antigen Peptide Sequences for SRSF2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ40890 fis, clone UTERU2001024, highly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 2 (B3KUY1_HUMAN)
  • cDNA FLJ52570, highly similar to Splicing factor, arginine/serine-rich 2 (B4DN89_HUMAN)
  • SFRS2 protein (Q6NXQ0_HUMAN)
  • cDNA FLJ36307 fis, clone THYMU2004906, moderately similar to SPLICING FACTOR, ARGININE/SERINE-RICH 2 (Q8N220_HUMAN)
  • cDNA FLJ35170 fis, clone PLACE6012942, highly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 2 (Q8NAK9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q01130

UniProtKB/Swiss-Prot:

SRSF2_HUMAN :
  • Belongs to the splicing factor SR family.
Family:
  • Belongs to the splicing factor SR family.
genes like me logo Genes that share domains with SRSF2: view

Function for SRSF2 Gene

Molecular function for SRSF2 Gene

UniProtKB/Swiss-Prot Function:
Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.
UniProtKB/Swiss-Prot Induction:
Accumulates in a hypoacetylated/phosphorylated form in response to cisplatin treatment.

Phenotypes From GWAS Catalog for SRSF2 Gene

Gene Ontology (GO) - Molecular Function for SRSF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003714 transcription corepressor activity NAS 15652350
GO:0003723 RNA binding IEA,IBA 21873635
GO:0005080 protein kinase C binding IEA --
GO:0005515 protein binding IPI 9237760
genes like me logo Genes that share ontologies with SRSF2: view
genes like me logo Genes that share phenotypes with SRSF2: view

Human Phenotype Ontology for SRSF2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SRSF2 Gene

MGI Knock Outs for SRSF2:

Animal Model Products

CRISPR Products

miRNA for SRSF2 Gene

miRTarBase miRNAs that target SRSF2

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SRSF2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SRSF2 Gene

Localization for SRSF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SRSF2 Gene

Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Note=Phosphorylation by SRPK2 provokes its redistribution from the nuclear specke to nucleoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SRSF2 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SRSF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA,IDA 15652350
GO:0005654 nucleoplasm IDA,TAS --
GO:0005681 spliceosomal complex IEA --
GO:0005737 cytoplasm IBA 21873635
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with SRSF2: view

Pathways & Interactions for SRSF2 Gene

genes like me logo Genes that share pathways with SRSF2: view

Pathways by source for SRSF2 Gene

SIGNOR curated interactions for SRSF2 Gene

Activates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for SRSF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000278 mitotic cell cycle IEA --
GO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA,IBA 21873635
GO:0000398 mRNA splicing, via spliceosome TAS --
GO:0006397 mRNA processing TAS 8530103
GO:0006405 RNA export from nucleus TAS --
genes like me logo Genes that share ontologies with SRSF2: view

Drugs & Compounds for SRSF2 Gene

(7) Drugs for SRSF2 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(3) Additional Compounds for SRSF2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SRSF2: view

Transcripts for SRSF2 Gene

mRNA/cDNA for SRSF2 Gene

2 REFSEQ mRNAs :
22 NCBI additional mRNA sequence :
11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SRSF2

Alternative Splicing Database (ASD) splice patterns (SP) for SRSF2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4
SP1:
SP2: - -
SP3: - -

Relevant External Links for SRSF2 Gene

GeneLoc Exon Structure for
SRSF2

Expression for SRSF2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SRSF2 Gene

Protein differential expression in normal tissues from HIPED for SRSF2 Gene

This gene is overexpressed in NK cells (8.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SRSF2 Gene



Protein tissue co-expression partners for SRSF2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SRSF2

SOURCE GeneReport for Unigene cluster for SRSF2 Gene:

Hs.584801

Evidence on tissue expression from TISSUES for SRSF2 Gene

  • Nervous system(5)
  • Lung(4.9)
  • Liver(4.8)
  • Bone marrow(4.7)
  • Intestine(4.7)
  • Spleen(4.5)
  • Kidney(4.5)
  • Skin(4.3)
  • Blood(4.2)
  • Stomach(4.1)
  • Heart(4)
  • Eye(3.4)
  • Pancreas(3.1)
  • Muscle(2.9)
  • Lymph node(2.8)
  • Thyroid gland(2.5)
  • Bone(2.5)
  • Adrenal gland(2.5)
genes like me logo Genes that share expression patterns with SRSF2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SRSF2 Gene

Orthologs for SRSF2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SRSF2 Gene

Organism Taxonomy Gene Similarity Type Details
Dog
(Canis familiaris)
Mammalia -- 31
  • 100 (a)
OneToMany
SRSF2 30
  • 90.95 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 100 (a)
OneToMany
Chimpanzee
(Pan troglodytes)
Mammalia SRSF2 30 31
  • 99.25 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia SRSF2 30 31
  • 92.01 (n)
OneToMany
Rat
(Rattus norvegicus)
Mammalia Srsf2 30
  • 90.05 (n)
Mouse
(Mus musculus)
Mammalia Srsf2 30 17 31
  • 87.78 (n)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 49 (a)
OneToMany
Chicken
(Gallus gallus)
Aves SRSF2 30 31
  • 83.41 (n)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 99 (a)
OneToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia MGC75633 30
Zebrafish
(Danio rerio)
Actinopterygii srsf2a 31
  • 83 (a)
ManyToMany
srsf2b 31
  • 80 (a)
ManyToMany
Dr.8481 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3833 30
Fruit Fly
(Drosophila melanogaster)
Insecta SC35 31
  • 61 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea rsp-4 31
  • 59 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.11125 31
  • 70 (a)
OneToMany
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.3433 30
Species where no ortholog for SRSF2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SRSF2 Gene

ENSEMBL:
Gene Tree for SRSF2 (if available)
TreeFam:
Gene Tree for SRSF2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SRSF2: view image

Paralogs for SRSF2 Gene

Paralogs for SRSF2 Gene

(18) SIMAP similar genes for SRSF2 Gene using alignment to 3 proteins:

  • SRSF2_HUMAN
  • J3KP15_HUMAN
  • J3QL05_HUMAN

Pseudogenes.org Pseudogenes for SRSF2 Gene

genes like me logo Genes that share paralogs with SRSF2: view

Variants for SRSF2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SRSF2 Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
rs1064796272 Uncertain Significance: not provided 76,736,271(-) GGGACCT/G NON_CODING_TRANSCRIPT_VARIANT,INFRAME_DELETION

Additional dbSNP identifiers (rs#s) for SRSF2 Gene

Structural Variations from Database of Genomic Variants (DGV) for SRSF2 Gene

Variant ID Type Subtype PubMed ID
nsv1110921 OTHER inversion 24896259
nsv828110 CNV gain 20364138
nsv833550 CNV loss 17160897

Variation tolerance for SRSF2 Gene

Residual Variation Intolerance Score: 26.4% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SRSF2 Gene

Human Gene Mutation Database (HGMD)
SRSF2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SRSF2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SRSF2 Gene

Disorders for SRSF2 Gene

MalaCards: The human disease database

(29) MalaCards diseases for SRSF2 Gene - From: Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
aggressive systemic mastocytosis
  • asm
systemic mastocytosis with associated hematologic neoplasm
  • sm-ahnmd
chronic myelomonocytic leukemia
  • leukemia, myelomonocytic, chronic
chronic neutrophilic leukemia
  • cnl
systemic mastocytosis
  • corneal dystrophy, subepithelial mucinous
- elite association - COSMIC cancer census association via MalaCards
Search SRSF2 in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with SRSF2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SRSF2 Gene

Publications for SRSF2 Gene

  1. Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells. (PMID: 14684736) Yang L … Cao X (The Journal of biological chemistry 2004) 3 4 23
  2. Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2). (PMID: 8530103) Bermingham JR … Rosenfeld MG (Genomics 1995) 2 3 23
  3. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. (PMID: 8261509) Wu JY … Maniatis T (Cell 1993) 3 4 23
  4. Isolation of a complementary DNA that encodes the mammalian splicing factor SC35. (PMID: 1373910) Fu XD … Maniatis T (Science (New York, N.Y.) 1992) 3 4 23
  5. NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. (PMID: 21296756) Kim YD … Jun CD (Nucleic acids research 2011) 3 4

Products for SRSF2 Gene