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SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009] See more...
Aliases for SRRM4 Gene
Aliases for SRRM4 Gene
- Serine/Arginine Repetitive Matrix 4 2 3 5
- Neural-Specific SR-Related Protein Of 100 KDa 2 3 4
- KIAA1853 2 3 4
- NSR100 2 3 4
- Neural-Specific Serine/Arginine Repetitive Splicing Factor Of 100 KDa 3 4
- Serine/Arginine Repetitive Matrix Protein 4 3 4
- Medulloblastoma Antigen MU-MB-2.76 3 4
- MU-MB-2.76 3
- SRRM4 5
External Ids for SRRM4 Gene
- HGNC: 29389
- Entrez Gene: 84530
- Ensembl: ENSG00000139767
- OMIM: 613103
- UniProtKB: A7MD48
Previous HGNC Symbols for SRRM4 Gene
- KIAA1853
Previous GeneCards Identifiers for SRRM4 Gene
- GC12P117903
- GC12P119420
- GC12P116428
Summaries for SRRM4 Gene
-
SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]
GeneCards Summary for SRRM4 Gene
SRRM4 (Serine/Arginine Repetitive Matrix 4) is a Protein Coding gene. Diseases associated with SRRM4 include Deafness, Autosomal Dominant 27 and Medulloblastoma. Gene Ontology (GO) annotations related to this gene include mRNA binding.
UniProtKB/Swiss-Prot Summary for SRRM4 Gene
-
Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity). Promotes alternative splicing of REST transcripts to produce REST isoform 3 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:30684677). Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions (By similarity).
Additional gene information for SRRM4 Gene
- HGNC(29389)
- Entrez Gene(84530)
- Ensembl(ENSG00000139767)
- OMIM(613103)
- UniProtKB(A7MD48)
- Open Targets Platform(ENSG00000139767)
- Monarch Initiative
- Search for SRRM4 at DataMed
- Search for SRRM4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SRRM4 Gene
Genomics for SRRM4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SRRM4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SRRM4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SRRM4
Genomic Locations for SRRM4 Gene
Genomic Locations for SRRM4 Gene
- chr12:118,981,541-119,163,051
- (GRCh38/hg38)
- Size:
- 181,511 bases
- Orientation:
- Plus strand
- chr12:119,419,300-119,600,856
- (GRCh37/hg19)
- Size:
- 181,557 bases
- Orientation:
- Plus strand
Genomic View for SRRM4 Gene
Genes around SRRM4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.23 by HGNC
- 12q24.23 by Entrez Gene
- 12q24.23 by Ensembl
SRRM4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SRRM4 Gene
Proteins for SRRM4 Gene
-
Protein details for SRRM4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A7MD48-SRRM4_HUMAN
- Recommended name:
- Serine/arginine repetitive matrix protein 4
- Protein Accession:
- A7MD48
- A8K5P6
- B2RZH7
- Q7Z5F0
- Q96JH4
Protein attributes for SRRM4 Gene
- Size:
- 611 amino acids
- Molecular mass:
- 68559 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB47482.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for SRRM4 Gene
Post-translational modifications for SRRM4 Gene
- Phosphorylated.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SRRM4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SRRM4
- Novus Biologicals Antibodies for SRRM4
- Invitrogen Antibodies for SRRM4 (AFLGC-SRRM4)
-
Biorbyt antibodies for SRRM4
- Sino Biological Antibodies for SRRM4
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SRRM4
- Origene Custom Protein Services for SRRM4
-
Signalway Proteins for SRRM4
No data available for DME Specific Peptides for SRRM4 Gene
Domains & Families for SRRM4 Gene
Gene Families for SRRM4 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for SRRM4 Gene
- GenScript: Design optimal peptide antigens:
-
- Neural-specific serine/arginine repetitive splicing factor of 100 kDa (SRRM4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
A7MD48- Family:
-
- Belongs to the nSR100 family.
Function for SRRM4 Gene
Molecular function for SRRM4 Gene
- UniProtKB/Swiss-Prot Function:
- Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity). Promotes alternative splicing of REST transcripts to produce REST isoform 3 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:30684677). Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions (By similarity).
Phenotypes From GWAS Catalog for SRRM4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0003729 | mRNA binding | IEA,ISS | -- |
Phenotypes for SRRM4 Gene
- MGI mutant phenotypes for SRRM4:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for SRRM4:
Animal Models for SRRM4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SRRM4 - Select products 50% OFF >
- * SRRM4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SRRM4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SRRM4
-
Santa Cruz Biotechnology (SCBT) CRISPR for SRRM4
miRNA for SRRM4 Gene
- miRTarBase miRNAs that target SRRM4
-
- mmu-let-7b-5p (MIRT012264)
- hsa-miR-511-5p (MIRT447561)
- hsa-miR-431-5p (MIRT447562)
- hsa-miR-298 (MIRT561071)
- hsa-miR-570-3p (MIRT561072)
- hsa-miR-922 (MIRT561073)
- mmu-miR-3065-5p (MIRT580728)
- mmu-miR-5114 (MIRT580729)
- mmu-miR-743a-3p (MIRT580730)
- mmu-miR-743b-3p (MIRT580731)
- mmu-miR-3087-3p (MIRT580732)
- mmu-miR-324-3p (MIRT580733)
- mmu-miR-1186a (MIRT600359)
- mmu-miR-302c-3p (MIRT600361)
- mmu-miR-672-5p (MIRT600362)
- hsa-miR-3167 (MIRT611858)
- hsa-miR-2113 (MIRT611859)
- hsa-miR-3679-3p (MIRT611860)
- hsa-miR-3942-3p (MIRT611861)
- hsa-miR-218-5p (MIRT611862)
- hsa-miR-636 (MIRT611863)
- hsa-miR-3160-5p (MIRT611864)
- hsa-miR-205-3p (MIRT611865)
- hsa-miR-208b-5p (MIRT611866)
- hsa-miR-208a-5p (MIRT611867)
- hsa-miR-8485 (MIRT622072)
- hsa-miR-568 (MIRT627514)
- hsa-miR-4742-3p (MIRT627515)
- hsa-miR-384 (MIRT653112)
- hsa-miR-3685 (MIRT653113)
- hsa-miR-647 (MIRT653114)
- hsa-miR-6772-3p (MIRT653115)
- hsa-miR-6762-3p (MIRT653116)
- hsa-miR-604 (MIRT653117)
- hsa-miR-4448 (MIRT653118)
- hsa-miR-4268 (MIRT653119)
- hsa-miR-4735-5p (MIRT653120)
- hsa-miR-3667-3p (MIRT653121)
- hsa-miR-6734-3p (MIRT653122)
- hsa-miR-6504-5p (MIRT653123)
- hsa-miR-3064-5p (MIRT653124)
- hsa-miR-6793-3p (MIRT653125)
- hsa-miR-7850-5p (MIRT666112)
- hsa-miR-5004-3p (MIRT666113)
- hsa-miR-432-3p (MIRT666114)
- hsa-miR-6867-3p (MIRT666115)
- hsa-miR-4685-3p (MIRT666116)
- hsa-miR-4287 (MIRT666117)
- hsa-miR-7113-3p (MIRT666118)
- hsa-miR-2116-3p (MIRT666119)
- hsa-miR-449b-3p (MIRT666120)
- hsa-miR-4524a-3p (MIRT681810)
- hsa-miR-6757-3p (MIRT778413)
- hsa-miR-6761-5p (MIRT778475)
- hsa-miR-5692a (MIRT787780)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SRRM4
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Clone Products
- Applied Biological Materials (abm): Clones for SRRM4 - Select products 50% OFF >
- * SRRM4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SRRM4
- Addgene plasmids for SRRM4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SRRM4
Cell Line Products
-
Horizon Cell Lines for SRRM4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SRRM4 Gene
Localization for SRRM4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SRRM4 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA,ISS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SRRM4 Gene
Pathways & Interactions for SRRM4 Gene
Interacting Proteins for SRRM4 Gene
Selected Interacting proteins:
A7MD48-SRRM4_HUMAN
ENSP00000267260
for SRRM4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SRRM4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | IEA,ISS | -- |
| GO:0006397 | mRNA processing | IBA,ISS | -- |
| GO:0007399 | nervous system development | IEA,ISS | -- |
| GO:0007605 | sensory perception of sound | IEA | -- |
| GO:0008380 | RNA splicing | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SRRM4 Gene
Transcripts for SRRM4 Gene
mRNA/cDNA for SRRM4 Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000267260 8431 nts (view in UCSC)
- ENST00000534886 455 nts (view in UCSC)
- ENST00000537597 561 nts (view in UCSC)
- ENST00000545224 461 nts (view in UCSC)
- ENST00000641899 682 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SRRM4 - Select products 50% OFF >
- * SRRM4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SRRM4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SRRM4
-
Santa Cruz Biotechnology (SCBT) CRISPR for SRRM4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SRRM4
- Browse OriGene Inhibitory RNA Products For SRRM4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SRRM4
Clone Products
- Applied Biological Materials (abm): Clones for SRRM4 - Select products 50% OFF >
- * SRRM4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SRRM4
- Addgene plasmids for SRRM4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SRRM4
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | ||||||||||||
| SP3: |
Relevant External Links for SRRM4 Gene
- GeneLoc Exon Structure for
- SRRM4
Expression for SRRM4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
mRNA differential expression in normal tissues according to GTEx for SRRM4 Gene
This gene is overexpressed in Brain - Cerebellum (x13.4), Brain - Cerebellar Hemisphere (x12.6), Brain - Cortex (x5.7), Brain - Frontal Cortex (BA9) (x5.2), and Brain - Anterior cingulate cortex (BA24) (x4.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SRRM4 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SRRM4
SOURCE GeneReport for Unigene cluster for SRRM4 Gene:
Hs.744964mRNA Expression by UniProt/SwissProt for SRRM4 Gene:
A7MD48-SRRM4_HUMAN
Tissue specificity:
Specifically expressed in neuronal cells (at protein level). Expressed in the cerebellum.
Evidence on tissue expression from TISSUES for SRRM4 Gene
- Nervous system(4.8)
Primer Products
-
OriGene qPCR primer pairs for SRRM4
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SRRM4 Gene
Orthologs for SRRM4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SRRM4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SRRM4 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SRRM4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Srrm4 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SRRM4 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SRRM4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| SRRM4 30 |
|
||||
| -- 31 |
|
OneToMany | |||
| Lizard (Anolis carolinensis) |
Reptilia | SRRM4 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | SRRM4 31 |
|
OneToOne |
- Species where no ortholog for SRRM4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SRRM4 Gene
- ENSEMBL:
- Gene Tree for SRRM4 (if available)
- TreeFam:
- Gene Tree for SRRM4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SRRM4: view image
Paralogs for SRRM4 Gene
No data available for Paralogs for SRRM4 Gene
Variants for SRRM4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SRRM4 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1555219792 | Uncertain Significance: not provided | 119,120,278(+) | T/C | SPLICE_DONOR_VARIANT | |
| rs2555273 | - | p.Arg547Ser | |||
| rs2723880 | - | p.Arg406Gln | |||
| rs7297606 | - | p.Ser243Asn |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1564n100 | CNV | loss | 25217958 |
| dgv309n67 | CNV | loss | 20364138 |
| esv2659059 | CNV | deletion | 23128226 |
| esv2665881 | CNV | deletion | 23128226 |
| esv2669850 | CNV | deletion | 23128226 |
| esv2746456 | CNV | deletion | 23290073 |
| esv275551 | CNV | gain+loss | 21479260 |
| esv3580498 | CNV | loss | 25503493 |
| esv3630896 | CNV | loss | 21293372 |
| esv3630897 | CNV | loss | 21293372 |
| esv3630898 | CNV | loss | 21293372 |
| esv3630899 | CNV | loss | 21293372 |
| nsv1069698 | CNV | deletion | 25765185 |
| nsv438238 | CNV | loss | 16468122 |
| nsv455725 | CNV | loss | 19166990 |
| nsv521985 | CNV | loss | 19592680 |
| nsv529044 | CNV | loss | 19592680 |
| nsv560395 | CNV | loss | 21841781 |
| nsv902 | CNV | deletion | 18451855 |
Residual Variation Intolerance Score:
58.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.70;
91.48% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SRRM4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SRRM4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SRRM4 Gene
Disorders for SRRM4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| deafness, autosomal dominant 27 |
|
|
| medulloblastoma |
|
|
| suppression of tumorigenicity 12 |
|
|
Search SRRM4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SRRM4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SRRM4 Gene
Publications for SRRM4 Gene
- Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein. (PMID: 19737518) Calarco JA … Blencowe BJ (Cell 2009) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries. (PMID: 12800201) Behrends U … Mautner J (International journal of cancer 2003) 3 4
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 3 4
ExternalLinks
Products for SRRM4 Gene
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- High-throughput Antibody Production Service
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- antibodies-online: Show 5 available SRRM4 Antibodies ranked by validation data
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- antibodies-online: Show 2 available SRRM4 Proteins ranked by validation data
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- Horizon Cell Lines for SRRM4
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- Biorbyt antibodies for SRRM4
- Signalway Proteins for SRRM4
Sources for SRRM4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
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- (33) SGD
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- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
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- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
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- (48) IMGT
- (49) Leiden
- (50) miRBase
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- (55) TGDB
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- (59) ProSpec
- (60) Sino Biological
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- (64) Proteopedia
- (65) MOPED
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- (67) Reactome
- (68) GeneGo (Thomson Reuters)
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- (70) SIMAP
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- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
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- (80) MaxQB
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- (82) BioGPS
- (83) Illumina
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- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
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- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
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- (104) diseasecard
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- (122) ENCODE
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- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (130) CIViC
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- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
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- (154) Biorbyt
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- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB