Aliases for SRRM1 Gene
External Ids for SRRM1 Gene
Previous GeneCards Identifiers for SRRM1 Gene
GeneCards Summary for SRRM1 Gene
SRRM1 (Serine And Arginine Repetitive Matrix 1) is a Protein Coding gene. Diseases associated with SRRM1 include Cortical Thymoma and Epithelial Malignant Thymoma. Among its related pathways are Gene Expression and Transport of Mature Transcript to Cytoplasm.
UniProtKB/Swiss-Prot Summary for SRRM1 Gene
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.