Aliases for SRP54 Gene
External Ids for SRP54 Gene
Previous GeneCards Identifiers for SRP54 Gene
GeneCards Summary for SRP54 Gene
SRP54 (Signal Recognition Particle 54) is a Protein Coding gene. Diseases associated with SRP54 include Neutropenia, Severe Congenital, 8, Autosomal Dominant and Shwachman-Diamond Syndrome 1. Among its related pathways are Viral mRNA Translation and Protein export. Gene Ontology (GO) annotations related to this gene include GTPase activity. An important paralog of this gene is SRPRA.
UniProtKB/Swiss-Prot Summary for SRP54 Gene
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development (PubMed:29914977, PubMed:28972538).