Aliases for SRMS Gene
External Ids for SRMS Gene
Previous HGNC Symbols for SRMS Gene
Previous GeneCards Identifiers for SRMS Gene
GeneCards Summary for SRMS Gene
SRMS (Src-Related Kinase Lacking C-Terminal Regulatory Tyrosine And N-Terminal Myristylation Sites) is a Protein Coding gene. Diseases associated with SRMS include Lung Sarcoma. Among its related pathways are Signaling by GPCR and Signaling by PTK6. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PTK6.
UniProtKB/Swiss-Prot Summary for SRMS Gene
Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907). Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907).