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SPRYD4 (SPRY Domain Containing 4) is a Protein Coding gene. An important paralog of this gene is RNF135.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0005515 | protein binding | IPI | 27499296 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 17852359 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008150 | biological_process | ND | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SPRYD4 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SPRYD4 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SPRYD4 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Spryd4 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Spryd4 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | SPRYD4 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SPRYD4 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SPRYD4 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | spryd4 30 31 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1592275599 | Likely Benign: not provided | 56,475,621(+) |
T/C NM_013267.4(GLS2):c.929+3A>G |
THREE_PRIME_UTR_VARIANT,INTRON | |
rs61731958 | Benign: not provided | 56,474,882(+) |
C/T NM_013267.4(GLS2):c.1011G>A (p.Gly337=) |
SYNONYMOUS_VARIANT,THREE_PRIME_UTR | |
rs2657881 | - |
p.Met50Thr |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2667114 | CNV | deletion | 23128226 |
esv3629598 | CNV | loss | 21293372 |
nsv1052713 | CNV | gain | 25217958 |
nsv482992 | CNV | gain+loss | 15286789 |
No disorders were found for SPRYD4 Gene.