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Aliases for SPRR2C Gene

Aliases for SPRR2C Gene

  • Small Proline Rich Protein 2C (Pseudogene) 2 3 5
  • Small Proline-Rich Protein 2C (Pseudogene) 2
  • Small Proline-Rich Protein 2C 2

External Ids for SPRR2C Gene

Previous GeneCards Identifiers for SPRR2C Gene

  • GC01M150928
  • GC01M148895
  • GC01M149887
  • GC01M150329
  • GC01M150228
  • GC01M149926
  • GC01U901201
  • GC01M151380
  • GC01M151381
  • GC01M124475

Summaries for SPRR2C Gene

GeneCards Summary for SPRR2C Gene

SPRR2C (Small Proline Rich Protein 2C (Pseudogene)) is a Pseudogene. Diseases associated with SPRR2C include Small Proline-Rich Protein 2C, Pseudogene.

Additional gene information for SPRR2C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPRR2C Gene

Genomics for SPRR2C Gene

GeneHancer (GH) Regulatory Elements for SPRR2C Gene

Promoters and enhancers for SPRR2C Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I153122 Enhancer 1.1 Ensembl ENCODE 29.2 +17.9 17893 2.5 CLOCK RB1 NEUROD1 KLF17 SIN3A FEZF1 YBX1 ZBTB40 RFX5 GLIS2 SPRR2C SPRR2G LELP1 SPRR2B SPRR2F
GH01I153099 Enhancer 0.6 ENCODE 12.4 +41.3 41321 2.3 JUN MAX CEBPB EP300 RAD21 JUND MAFF CREB1 STAT3 SMC3 SPRR2C SPRR1B SPRR2F SPRR2E SPRR2B
GH01I153094 Promoter 0.5 EPDnew 10.6 +46.9 46948 0.1 SPRR2E SPRR2B SPRR2C LELP1 SPRR2F
GH01I153119 Enhancer 0.6 ENCODE 0.3 +21.9 21902 0.4 MEIS2 LEF1 PKNOX1 RFX1 SOX6 NR4A1 CBFA2T3 DPF2 ZEB2 CTBP1 SPRR2G SPRR2B SPRR2F SPRR2C
GH01I153135 Enhancer 0.4 ENCODE 0.4 +5.9 5885 0.6 RFX1 BMI1 SPRR2C SPRR2F
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SPRR2C on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SPRR2C gene promoter:

Genomic Locations for SPRR2C Gene

Genomic Locations for SPRR2C Gene
chr1:153,140,118-153,141,493
(GRCh38/hg38)
Size:
1,376 bases
Orientation:
Minus strand
chr1:153,112,594-153,113,969
(GRCh37/hg19)

Genomic View for SPRR2C Gene

Genes around SPRR2C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPRR2C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPRR2C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPRR2C Gene

Proteins for SPRR2C Gene

Post-translational modifications for SPRR2C Gene

No Post-translational modifications

No data available for DME Specific Peptides for SPRR2C Gene

Domains & Families for SPRR2C Gene

Gene Families for SPRR2C Gene

Suggested Antigen Peptide Sequences for SPRR2C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPRR2C: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for SPRR2C Gene

Function for SPRR2C Gene

Molecular function for SPRR2C Gene

GENATLAS Biochemistry:
small proline rich protein 2C,precursor of cornified cell envelope,cornifin,clustered in the epidermal differentiation complex (EDC)

Animal Model Products

miRNA for SPRR2C Gene

miRTarBase miRNAs that target SPRR2C

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPRR2C Gene

Localization for SPRR2C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SPRR2C Gene

Pathways & Interactions for SPRR2C Gene

SuperPathways for SPRR2C Gene

No Data Available

Interacting Proteins for SPRR2C Gene

Gene Ontology (GO) - Biological Process for SPRR2C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SPRR2C Gene

Drugs & Compounds for SPRR2C Gene

No Compound Related Data Available

Transcripts for SPRR2C Gene

mRNA/cDNA for SPRR2C Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPRR2C Gene

Small proline-rich protein 2C (pseudogene):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPRR2C Gene

No ASD Table

Relevant External Links for SPRR2C Gene

GeneLoc Exon Structure for
SPRR2C
ECgene alternative splicing isoforms for
SPRR2C

Expression for SPRR2C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SPRR2C Gene

mRNA differential expression in normal tissues according to GTEx for SPRR2C Gene

This gene is overexpressed in Esophagus - Mucosa (x30.3), Minor Salivary Gland (x9.3), and Testis (x6.4).

NURSA nuclear receptor signaling pathways regulating expression of SPRR2C Gene:

SPRR2C

SOURCE GeneReport for Unigene cluster for SPRR2C Gene:

Hs.2421
genes like me logo Genes that share expression patterns with SPRR2C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPRR2C Gene

Orthologs for SPRR2C Gene

Evolution for SPRR2C Gene

ENSEMBL:
Gene Tree for SPRR2C (if available)
TreeFam:
Gene Tree for SPRR2C (if available)

No data available for Orthologs for SPRR2C Gene

Paralogs for SPRR2C Gene

No data available for Paralogs for SPRR2C Gene

Variants for SPRR2C Gene

Sequence variations from dbSNP and Humsavar for SPRR2C Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000555941 -- 153,141,813(-) G/A upstream_transcript_variant
rs1000807392 -- 153,142,859(-) G/C upstream_transcript_variant
rs1001109664 -- 153,142,506(-) T/C upstream_transcript_variant
rs1001656742 -- 153,141,701(-) T/C upstream_transcript_variant
rs1001993641 -- 153,143,386(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SPRR2C Gene

Variant ID Type Subtype PubMed ID
nsv946397 CNV duplication 23825009
nsv547899 CNV gain 21841781
nsv2921 CNV insertion 18451855
nsv1004168 CNV loss 25217958

Additional Variant Information for SPRR2C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SPRR2C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SPRR2C Gene

Disorders for SPRR2C Gene

MalaCards: The human disease database

(1) MalaCards diseases for SPRR2C Gene - From: OMIM and GeneCards

Disorder Aliases PubMed IDs
small proline-rich protein 2c, pseudogene
  • sprr2c
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SPRR2C

genes like me logo Genes that share disorders with SPRR2C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SPRR2C Gene

Publications for SPRR2C Gene

  1. Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. (PMID: 8325635) Gibbs S … Backendorf C (Genomics 1993) 2 3 58
  2. Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes. (PMID: 3133554) Kartasova T … van de Putte P (Molecular and cellular biology 1988) 2 3 58
  3. MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus. (PMID: 19342367) Maru DM … Luthra R (The American journal of pathology 2009) 22 58
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U … Wanker EE (Cell 2005) 3 58
  5. Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus. (PMID: 15232223) Hong SH … Kim MK (Molecules and cells 2004) 3 58

Products for SPRR2C Gene

Sources for SPRR2C Gene

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