Aliases for SPPL2C Gene
External Ids for SPPL2C Gene
Previous GeneCards Identifiers for SPPL2C Gene
GeneCards Summary for SPPL2C Gene
SPPL2C (Signal Peptide Peptidase Like 2C) is a Protein Coding gene. Diseases associated with SPPL2C include Koolen-De Vries Syndrome. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and aspartic-type endopeptidase activity. An important paralog of this gene is SPPL2B.
UniProtKB/Swiss-Prot Summary for SPPL2C Gene
Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.