Aliases for SPON2 Gene
External Ids for SPON2 Gene
Previous GeneCards Identifiers for SPON2 Gene
GeneCards Summary for SPON2 Gene
SPON2 (Spondin 2) is a Protein Coding gene. Diseases associated with SPON2 include Drug-Induced Lupus Erythematosus. Among its related pathways are Metabolism of proteins and ERK Signaling. Gene Ontology (GO) annotations related to this gene include antigen binding and lipopolysaccharide binding. An important paralog of this gene is THSD7A.
UniProtKB/Swiss-Prot Summary for SPON2 Gene
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).