Aliases for SPOCK1 Gene
External Ids for SPOCK1 Gene
Previous HGNC Symbols for SPOCK1 Gene
Previous GeneCards Identifiers for SPOCK1 Gene
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
GeneCards Summary for SPOCK1 Gene
SPOCK1 (SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 1) is a Protein Coding gene. Diseases associated with SPOCK1 include Chylothorax, Congenital and Coproporphyria, Hereditary. Among its related pathways are ERK Signaling and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include calcium ion binding and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SPOCK3.
UniProtKB/Swiss-Prot Summary for SPOCK1 Gene
May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.