Aliases for SPOCK1 Gene
External Ids for SPOCK1 Gene
Previous HGNC Symbols for SPOCK1 Gene
Previous GeneCards Identifiers for SPOCK1 Gene
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
GeneCards Summary for SPOCK1 Gene
SPOCK1 (SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 1) is a Protein Coding gene. Diseases associated with SPOCK1 include Deafness, Autosomal Recessive 101 and Gingival Overgrowth. Among its related pathways are Integrin Pathway and Phospholipase-C Pathway. Gene Ontology (GO) annotations related to this gene include calcium ion binding and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SPOCK3.
UniProtKB/Swiss-Prot Summary for SPOCK1 Gene
May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.