Aliases for SPINK6 Gene
External Ids for SPINK6 Gene
Previous GeneCards Identifiers for SPINK6 Gene
The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene. [provided by RefSeq, Aug 2010]
GeneCards Summary for SPINK6 Gene
SPINK6 (Serine Peptidase Inhibitor Kazal Type 6) is a Protein Coding gene. Diseases associated with SPINK6 include Pompholyx. Among its related pathways are Keratinization and Developmental Biology. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SPINK5.
UniProtKB/Swiss-Prot Summary for SPINK6 Gene
Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.