Aliases for SPECC1L Gene
Aliases for SPECC1L Gene
External Ids for SPECC1L Gene
- HGNC: 29022
- Entrez Gene: 23384
- Ensembl: ENSG00000100014
- OMIM: 614140
- UniProtKB: Q69YQ0
Previous HGNC Symbols for SPECC1L Gene
- CYTSA
Previous GeneCards Identifiers for SPECC1L Gene
- GC22P022996
- GC22P007616
- GC22P024668
- GC22P024682
- GC22P024692
- GC22P024708
- GC22P024731
- GC22P024272
- GC22P024297
- GC22P024314
- GC22P024329
- GC22P024341
- GC22P024365
- GC22P024387
Summaries for SPECC1L Gene
-
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
GeneCards Summary for SPECC1L Gene
SPECC1L (Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1 Like) is a Protein Coding gene. Diseases associated with SPECC1L include Facial Clefting, Oblique, 1 and Opitz Gbbb Syndrome, Type Ii. Gene Ontology (GO) annotations related to this gene include protein dimerization activity. An important paralog of this gene is SPECC1L-ADORA2A.
UniProtKB/Swiss-Prot for SPECC1L Gene
-
Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
Additional gene information for SPECC1L Gene
- Monarch Initiative
- Search for SPECC1L at DataMed
- Search for SPECC1L at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPECC1L Gene
Genomics for SPECC1L Gene
GeneHancer (GH) Regulatory Elements for SPECC1L Gene
Promoters and enhancers for SPECC1L Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SPECC1L on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for SPECC1L Gene
Genomic Locations for SPECC1L Gene
- chr22:24,270,817-24,417,740
- (GRCh38/hg38)
- Size:
- 146,924 bases
- Orientation:
- Plus strand
- chr22:24,666,786-24,813,708
- (GRCh37/hg19)
Genomic View for SPECC1L Gene
Genes around SPECC1L on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.23 by Ensembl
- 22q11.23 by Entrez Gene
- 22q11.23 by HGNC
SPECC1L Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SPECC1L Gene
Proteins for SPECC1L Gene
-
Protein details for SPECC1L Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q69YQ0-CYTSA_HUMAN
- Recommended name:
- Cytospin-A
- Protein Accession:
- Q69YQ0
- B7Z758
- F5H1H6
- O15081
Protein attributes for SPECC1L Gene
- Size:
- 1117 amino acids
- Molecular mass:
- 124602 Da
- Quaternary structure:
-
- May interact with both microtubules and actin cytoskeleton.
Protein Expression for SPECC1L Gene
Post-translational modifications for SPECC1L Gene
Other Protein References for SPECC1L Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SPECC1L
- Novus Biologicals Antibodies for SPECC1L
- Invitrogen Antibodies for SPECC1L
- Search GeneTex for Antibodies for SPECC1L
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SPECC1L
- Origene Custom Protein Services for SPECC1L
- Novus Biologicals proteins for SPECC1L
- Search GeneTex for Proteins for SPECC1L
Assay Products
No data available for DME Specific Peptides for SPECC1L Gene
Domains & Families for SPECC1L Gene
Gene Families for SPECC1L Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
Protein Domains for SPECC1L Gene
Suggested Antigen Peptide Sequences for SPECC1L Gene
Graphical View of Domain Structure for InterPro Entry
Q69YQ0- Family:
-
- Belongs to the cytospin-A family.
Function for SPECC1L Gene
Molecular function for SPECC1L Gene
- UniProtKB/Swiss-Prot Function:
- Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
Phenotypes for SPECC1L Gene
- GenomeRNAi human phenotypes for SPECC1L:
Animal Model Products
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- Cyagen custom Knockout/knockin (KOKI) mouse models for SPECC1L
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SPECC1L gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPECC1L gene
- Search ViGene Biosciences for SPECC1L
CRISPR Products
-
OriGene CRISPR knockouts for SPECC1L
- genomics-online: gRNA clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- Applied Biological Materials CRISPR for SPECC1L
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPECC1L
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miRNA for SPECC1L Gene
- miRTarBase miRNAs that target SPECC1L
-
- hsa-mir-26b-5p (MIRT029692)
- hsa-mir-1301-3p (MIRT036003)
- hsa-mir-421 (MIRT039398)
- hsa-mir-18a-3p (MIRT040797)
- hsa-mir-484 (MIRT042319)
- hsa-mir-339-5p (MIRT042765)
- hsa-mir-186-5p (MIRT045308)
- hsa-mir-146a-3p (MIRT737640)
- hsa-mir-301a-5p (MIRT739618)
- hsa-mir-301b-5p (MIRT739628)
- hsa-mir-3921 (MIRT742970)
- hsa-mir-4294 (MIRT743782)
- hsa-mir-4433a-3p (MIRT744369)
- hsa-mir-4653-5p (MIRT746618)
- hsa-mir-4706 (MIRT747343)
- hsa-mir-4734 (MIRT747982)
- hsa-mir-4749-5p (MIRT748323)
- hsa-mir-4787-5p (MIRT748895)
- hsa-mir-593-3p (MIRT751591)
- hsa-mir-665 (MIRT753660)
- hsa-mir-744-5p (MIRT759370)
miRNA Products
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Inhibitory RNA Products
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Clone Products
- VectorBuilder custom plasmid, inducible vectors for SPECC1L
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SPECC1L
-
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Cell Line Products
-
Horizon Cell Lines for SPECC1L
-
ViGene Biosciences adenoviral particle packaged cDNA for SPECC1L gene
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SPECC1L Gene
Localization for SPECC1L Gene
Subcellular locations from UniProtKB/Swiss-Prot for SPECC1L Gene
- Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 4 |
| cytosol | 4 |
- Actin filaments (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005819 | spindle | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005921 | gap junction | IEA | -- |
| GO:0015629 | actin cytoskeleton | IDA | -- |
Pathways & Interactions for SPECC1L Gene
No Data Available
Interacting Proteins for SPECC1L Gene
Selected Interacting proteins:
ENSP00000325785
Q69YQ0-CYTSA_HUMAN
for SPECC1L Gene via
STRING
MINT
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007155 | cell adhesion | IDA | 21703590 |
| GO:0051301 | cell division | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SPECC1L Gene
Drugs & Compounds for SPECC1L Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Methotrexate | Approved | Pharma | Folate antagonist,inhibits DFHR | 1603 |
Transcripts for SPECC1L Gene
mRNA/cDNA for SPECC1L Gene
- (4) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (228) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SPECC1L Gene
CRISPR Products
-
OriGene CRISPR knockouts for SPECC1L
- genomics-online: gRNA clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- Applied Biological Materials CRISPR for SPECC1L
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPECC1L
- GenScript: Design CRISPR guide RNA sequences for SPECC1L
miRNA Products
- Search ViGene Biosciences for SPECC1L
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SPECC1L
- Browse OriGene Inhibitory RNA Products For SPECC1L
- genomics-online: shRNA clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SPECC1L gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for SPECC1L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPECC1L
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SPECC1L
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: |
| ExUns: | 19b |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: |
Expression for SPECC1L Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Testis Somatic Cells Primitive Gonad
-
Gonad (Reproductive System)
- Testis Somatic Cells Primitive Gonad
This gene is overexpressed in Bone marrow stromal cell (20.3), Adrenal (13.2), and Cervix (12.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SPECC1L Gene
NURSA nuclear receptor signaling pathways regulating expression of SPECC1L Gene:
SPECC1LSOURCE GeneReport for Unigene cluster for SPECC1L Gene:
Hs.474384Evidence on tissue expression from TISSUES for SPECC1L Gene
- Nervous system(4.8)
- Liver(4.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for SPECC1L Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cerebellum
- cheek
- chin
- cranial nerve
- ear
- epiglottis
- eye
- eyelid
- face
- forehead
- head
- jaw
- larynx
- lip
- mandible
- maxilla
- middle ear
- mouth
- neck
- nose
- outer ear
- pharynx
- scalp
- skull
- tongue
- vocal cord
Thorax:
- aorta
- bronchus
- diaphragm
- esophagus
- heart
- heart valve
- lung
- trachea
Abdomen:
- abdominal wall
- gallbladder
- intestine
- kidney
- large intestine
- stomach
Pelvis:
- anus
- penis
- rectum
- testicle
- ureter
- urethra
Limb:
- digit
- finger
- foot
- hand
- lower limb
- toe
- upper limb
General:
- blood
- blood vessel
- hair
- peripheral nervous system
- skin
Primer Products
-
OriGene qPCR primer pairs for SPECC1L
- genomics-online: primer clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SPECC1L Gene
Orthologs for SPECC1L Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SPECC1L 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| SPECC1L 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | SPECC1L 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Specc1l 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Specc1l 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | SPECC1L 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | specc1l 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | specc1la 33 34 |
|
||
| specc1lb 34 |
|
ManyToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG13366 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3677 34 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.3747 33 |
|
- Species where no ortholog for SPECC1L was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for SPECC1L Gene
Paralogs for SPECC1L Gene
(3) SIMAP similar genes for SPECC1L Gene using alignment to 3 proteins:
Variants for SPECC1L Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193920978 | uncertain-significance, Malignant tumor of prostate | 24,321,444(+) | G/A/T | coding_sequence_variant, genic_upstream_transcript_variant, missense_variant | |
| rs387907108 | pathogenic, Oculomaxillofacial dysostosis | 24,322,224(+) | A/C | coding_sequence_variant, genic_upstream_transcript_variant, missense_variant | |
| rs786201030 | pathogenic, Opitz G/BBB syndrome | 24,322,169(+) | A/C | coding_sequence_variant, genic_upstream_transcript_variant, missense_variant | |
| rs786201031 | pathogenic, Opitz G/BBB syndrome | 24,412,690(+) | G/A | coding_sequence_variant, missense_variant | |
| VAR_066873 | Facial clefting, oblique, 1 (OBLFC1) [MIM:600251] | p.Gln415Pro |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4528n100 | CNV | gain | 25217958 |
| dgv8039n54 | CNV | gain | 21841781 |
| esv24290 | CNV | gain | 19812545 |
| esv2724041 | CNV | deletion | 23290073 |
| esv2724068 | CNV | deletion | 23290073 |
| esv3575443 | CNV | gain | 25503493 |
| esv3893463 | CNV | gain | 25118596 |
| esv996036 | CNV | deletion | 20482838 |
| nsv1055830 | CNV | gain | 25217958 |
| nsv1057819 | CNV | gain | 25217958 |
| nsv1110863 | OTHER | inversion | 24896259 |
| nsv526567 | CNV | gain | 19592680 |
| nsv588744 | CNV | gain | 21841781 |
| nsv7350 | OTHER | inversion | 18451855 |
| nsv834158 | CNV | gain | 17160897 |
| nsv834160 | CNV | gain | 17160897 |
| nsv953060 | CNV | duplication | 24416366 |
| nsv953061 | CNV | deletion | 24416366 |
| nsv964609 | CNV | duplication | 23825009 |
| nsv964610 | CNV | duplication | 23825009 |
| nsv966093 | CNV | duplication | 23825009 |
| nsv979658 | CNV | duplication | 23825009 |
| nsv9883 | CNV | gain+loss | 18304495 |
| nsv9884 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
17.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.67;
57.00% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SPECC1L Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPECC1L Gene
Disorders for SPECC1L Gene
(11) MalaCards diseases for SPECC1L Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| facial clefting, oblique, 1 |
|
|
| opitz gbbb syndrome, type ii |
|
|
| opitz-gbbb syndrome |
|
|
| oculomaxillofacial dysostosis |
|
|
| hypertelorism, teebi type |
|
|
Search SPECC1L in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
CYTSA_HUMAN- Facial clefting, oblique, 1 (OBLFC1) [MIM:600251]: A rare form of facial clefting. A facial cleft is any of the fissures between the embryonic prominences that normally unite to form the face. {ECO:0000269 PubMed:21703590}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Opitz GBBB syndrome 2 (GBBB2) [MIM:145410]: A form of Opitz GBBB syndrome, a congenital midline malformation syndrome characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, cleft lip/palate, laryngotracheoesophageal abnormalities, imperforate anus, developmental delay and congenital heart defects. {ECO:0000269 PubMed:25412741}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for SPECC1L
No data available for Genatlas for SPECC1L Gene
Publications for SPECC1L Gene
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1997) 2 3 4 58
- Mutations in SPECC1L, encoding sperm antigen with calponin homology and coiled-coil domains 1-like, are found in some cases of autosomal dominant Opitz G/BBB syndrome. (PMID: 25412741) Kruszka P … Zackai EH (Journal of medical genetics 2015) 3 4 58
- Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. (PMID: 21703590) Saadi I … Maas RL (American journal of human genetics 2011) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Antigens recognized by autologous antibody in patients with renal-cell carcinoma. (PMID: 10508479) Scanlan MJ … Old LJ (International journal of cancer 1999) 3 4 58
Products for SPECC1L Gene
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- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
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- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for SPECC1L
- Novus Biologicals proteins for SPECC1L
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPECC1L
- VectorBuilder custom plasmid, inducible vectors for SPECC1L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPECC1L
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 41 available SPECC1L Antibodies ranked by validation data
- Compare Top SPECC1L Antibodies
- antibodies-online: Search results for available SPECC1L related products ranked by validation data
- antibodies-online: Search results for available SPECC1L related products ranked by validation data
- Search GeneTex for Antibodies for SPECC1L
- Search GeneTex for Proteins for SPECC1L
- ViGene Biosciences adenoviral particle packaged cDNA for SPECC1L gene
- ViGene Biosciences lentiviral particle packaged cDNA for SPECC1L gene
- ViGene Biosciences ready-to-package AAV shRNAs for SPECC1L gene
- Search ViGene Biosciences for SPECC1L
- Horizon Cell Lines for SPECC1L
- genomics-online: cdna clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- orf clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- genomics-online: gRNA clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- genomics-online: primer clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
- genomics-online: shRNA clones - Search results for 90 available SPECC1L gene related products
- Overview of 90 available SPECC1L gene related products
Sources for SPECC1L Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems