Aliases for SPCS3 Gene
External Ids for SPCS3 Gene
Previous GeneCards Identifiers for SPCS3 Gene
GeneCards Summary for SPCS3 Gene
SPCS3 (Signal Peptidase Complex Subunit 3) is a Protein Coding gene. Diseases associated with SPCS3 include Omsk Hemorrhagic Fever and Retinitis Pigmentosa 29. Among its related pathways are Incretin synthesis, secretion, and inactivation and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include peptidase activity.
UniProtKB/Swiss-Prot Summary for SPCS3 Gene
Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
(Microbial infection) Plays an important role in virion production of flaviviruses such as West Nile virus, Japanese enchephalitis virus, Dengue virus type 2 and Yellow Fever virus.