Free for academic non-profit institutions. Other users need a Commercial license
Aliases for SPC24 Gene
Aliases for SPC24 Gene
External Ids for SPC24 Gene
- HGNC: 26913
- Entrez Gene: 147841
- Ensembl: ENSG00000161888
- OMIM: 609394
- UniProtKB: Q8NBT2
Previous HGNC Symbols for SPC24 Gene
- SPBC24
Previous GeneCards Identifiers for SPC24 Gene
- GC19M011119
- GC19M011257
- GC19M010834
Summaries for SPC24 Gene
GeneCards Summary for SPC24 Gene
SPC24 (SPC24 Component Of NDC80 Kinetochore Complex) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Mitotic Prometaphase.
UniProtKB/Swiss-Prot Summary for SPC24 Gene
-
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
Additional gene information for SPC24 Gene
- HGNC(26913)
- Entrez Gene(147841)
- Ensembl(ENSG00000161888)
- OMIM(609394)
- UniProtKB(Q8NBT2)
- Open Targets Platform(ENSG00000161888)
- Search for SPC24 at DataMed
- Search for SPC24 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SPC24 Gene
Genomics for SPC24 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SPC24 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SPC24 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SPC24
- Top Transcription factor binding sites by QIAGEN in the SPC24 gene promoter:
-
- Arnt
- ER-alpha
- GR
- GR-alpha
- GR-beta
- MIF-1
- p300
- Pax-6
- SEF-1 (1)
- XBP-1
Genomic Locations for SPC24 Gene
Genomic Locations for SPC24 Gene
- chr19:11,131,520-11,155,997
- (GRCh38/hg38)
- Size:
- 24,478 bases
- Orientation:
- Minus strand
- chr19:11,242,196-11,266,484
- (GRCh37/hg19)
- Size:
- 24,289 bases
- Orientation:
- Minus strand
Genomic View for SPC24 Gene
Genes around SPC24 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by HGNC
- 19p13.2 by Entrez Gene
- 19p13.2 by Ensembl
SPC24 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SPC24 Gene
Proteins for SPC24 Gene
-
Protein details for SPC24 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NBT2-SPC24_HUMAN
- Recommended name:
- Kinetochore protein Spc24
- Protein Accession:
- Q8NBT2
- B4DZZ7
- C9JGC4
Protein attributes for SPC24 Gene
- Size:
- 197 amino acids
- Molecular mass:
- 22478 Da
- Quaternary structure:
-
- Component of the NDC80 complex, which consists of NDC80/HEC1, CDCA1, SPBC24 and SPBC25. The NDC80 complex is formed by two subcomplexes composed of NDC80/HEC1-CDCA1 and SPBC24-SPBC25. Each subcomplex is formed by parallel interactions through the coiled-coil domains of individual subunits. Formation of a tetrameric complex is mediated by interactions between the C-terminal regions of both subunits of the NDC80/HEC1-CDCA1 subcomplex and the N-terminal regions of both subunits of the SPBC24-SPBC25 complex. The tetrameric NDC80 complex has an elongated rod-like structure with globular domains at either end.
Protein Expression for SPC24 Gene
Post-translational modifications for SPC24 Gene
Other Protein References for SPC24 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SPC24
-
Abcam antibodies for SPC24
- Invitrogen Antibodies for SPC24 (AFLGC-SPC24)
- antibodies-online: Show 8 available SPC24 Antibodies ranked by validation data
- Compare Top SPC24 Antibodies
-
Quality Products:
-
Boster Bio Antibodies for SPC24
- Sino Biological Antibodies for SPC24
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for SPC24
- Origene Custom Protein Services for SPC24
- antibodies-online: Show 8 available SPC24 Proteins ranked by validation data
- Compare Top SPC24 Proteins
-
Quality Products:
-
Abcam proteins for SPC24
Assay Products
-
Signalway ELISA kits for SPC24
No data available for DME Specific Peptides for SPC24 Gene
Domains & Families for SPC24 Gene
Gene Families for SPC24 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SPC24 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SPC24 Gene
- GenScript: Design optimal peptide antigens:
-
- Kinetochore protein Spc24 (SPC24_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8NBT2- Family:
-
- Belongs to the SPC24 family.
Function for SPC24 Gene
Molecular function for SPC24 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
Phenotypes From GWAS Catalog for SPC24 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 14738735 |
Phenotypes for SPC24 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SPC24 - Select products 50% OFF >
- * SPC24 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SPC24
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SPC24
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPC24
miRNA for SPC24 Gene
- miRTarBase miRNAs that target SPC24
-
- hsa-miR-1-3p (MIRT023587)
- hsa-miR-92b-3p (MIRT040615)
- mmu-miR-129-5p (MIRT585775)
- mmu-miR-5101 (MIRT585776)
- mmu-miR-335-3p (MIRT585777)
- mmu-miR-1896 (MIRT585778)
- mmu-miR-129-1-3p (MIRT585779)
- mmu-miR-129-2-3p (MIRT585780)
- mmu-miR-3085-3p (MIRT585781)
- mmu-miR-3064-5p (MIRT585782)
- mmu-miR-717 (MIRT597174)
- mmu-miR-3097-3p (MIRT597175)
- mmu-miR-329-3p (MIRT597176)
- mmu-miR-362-3p (MIRT597177)
- mmu-miR-127-3p (MIRT597178)
- mmu-miR-466g (MIRT597179)
- mmu-miR-674-5p (MIRT597180)
- mmu-miR-3473d (MIRT597181)
- mmu-miR-3473c (MIRT597182)
- mmu-miR-883b-3p (MIRT597183)
- mmu-miR-883a-3p (MIRT597184)
- mmu-miR-466q (MIRT597185)
- hsa-miR-6888-3p (MIRT625029)
- hsa-miR-3120-5p (MIRT625030)
- hsa-miR-372-5p (MIRT625031)
- hsa-miR-371a-5p (MIRT625032)
- hsa-miR-616-5p (MIRT625033)
- hsa-miR-373-5p (MIRT625034)
- hsa-miR-371b-5p (MIRT625035)
- hsa-miR-6834-3p (MIRT625036)
- hsa-miR-3664-5p (MIRT625037)
- hsa-miR-3156-5p (MIRT625038)
- hsa-miR-665 (MIRT630982)
- hsa-miR-4443 (MIRT630983)
- hsa-miR-6515-5p (MIRT630984)
- hsa-miR-6514-3p (MIRT630985)
- hsa-miR-7977 (MIRT630986)
- hsa-miR-650 (MIRT630987)
- hsa-miR-3612 (MIRT630988)
- hsa-miR-6811-3p (MIRT630989)
- hsa-miR-214-5p (MIRT630990)
- hsa-miR-5690 (MIRT630991)
- hsa-miR-4684-5p (MIRT715709)
- hsa-miR-4738-3p (MIRT715710)
- hsa-miR-3675-3p (MIRT715711)
- hsa-miR-1273a (MIRT761801)
- hsa-miR-340-3p (MIRT765739)
- hsa-miR-3613-3p (MIRT766003)
- hsa-miR-3672 (MIRT766604)
- hsa-miR-4486 (MIRT769641)
- hsa-miR-4649-5p (MIRT770718)
- hsa-miR-4797-5p (MIRT772529)
- hsa-miR-5586-3p (MIRT774778)
- hsa-miR-6512-3p (MIRT776949)
- hsa-miR-661 (MIRT777466)
- hsa-miR-6720-5p (MIRT777795)
- hsa-miR-6729-5p (MIRT777963)
- hsa-miR-6827-3p (MIRT779937)
- hsa-miR-6849-3p (MIRT780348)
- hsa-miR-6864-3p (MIRT780631)
- hsa-miR-759 (MIRT781767)
- hsa-miR-873-3p (MIRT782475)
- hsa-miR-939-3p (MIRT782839)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SPC24
- Browse OriGene Inhibitory RNA Products For SPC24
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SPC24
Clone Products
- Applied Biological Materials (abm): Clones for SPC24 - Select products 50% OFF >
- * SPC24 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SPC24
- Addgene plasmids for SPC24
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SPC24
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPC24 Gene
Localization for SPC24 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SPC24 Gene
- Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. {ECO:0000269 PubMed:14738735}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| cytoskeleton | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
- Nucleoli (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IEA | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
Pathways & Interactions for SPC24 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Mitotic Metaphase and Anaphase |
.94
|
|
| 3 | Mitotic Prometaphase | ||
| 4 | Signaling by Rho GTPases | ||
| 5 | Signaling by GPCR | ||
Pathways by source for SPC24 Gene
1 BioSystems pathway for SPC24 Gene
12 Reactome pathways for SPC24 Gene
Interacting Proteins for SPC24 Gene
Selected Interacting proteins:
Q8NBT2-SPC24_HUMAN
ENSP00000465075
for SPC24 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SPC24
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0051301 | cell division | IEA | -- |
No data available for SIGNOR curated interactions for SPC24 Gene
Transcripts for SPC24 Gene
mRNA/cDNA for SPC24 Gene
- 4 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000423327 840 nts (view in UCSC)
- ENST00000585486 699 nts (view in UCSC)
- ENST00000585567 633 nts (view in UCSC)
- ENST00000586708 378 nts (view in UCSC)
- ENST00000591396 832 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SPC24 - Select products 50% OFF >
- * SPC24 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SPC24
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SPC24
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPC24
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SPC24
- Browse OriGene Inhibitory RNA Products For SPC24
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SPC24
Clone Products
- Applied Biological Materials (abm): Clones for SPC24 - Select products 50% OFF >
- * SPC24 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SPC24
- Addgene plasmids for SPC24
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SPC24
Relevant External Links for SPC24 Gene
- GeneLoc Exon Structure for
- SPC24
Expression for SPC24 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
This gene is overexpressed in Bone (26.5), Lung (14.2), Pancreas (9.9), and Fetal ovary (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SPC24 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SPC24
SOURCE GeneReport for Unigene cluster for SPC24 Gene:
Hs.381225Primer Products
-
OriGene qPCR primer pairs for SPC24
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPC24 Gene
Orthologs for SPC24 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SPC24 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SPC24 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SPC24 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Spc24 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Spc24 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SPC24 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SPC24 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SPC24 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | spc24 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | spc24 30 31 |
|
OneToOne |
- Species where no ortholog for SPC24 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SPC24 Gene
- ENSEMBL:
- Gene Tree for SPC24 (if available)
- TreeFam:
- Gene Tree for SPC24 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SPC24: view image
Paralogs for SPC24 Gene
No data available for Paralogs for SPC24 Gene
Variants for SPC24 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3427n100 | CNV | gain | 25217958 |
| nsv1065030 | CNV | gain | 25217958 |
| nsv833751 | CNV | loss | 17160897 |
Gene Damage Index Score:
3.53;
55.61% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SPC24 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SPC24 Gene
Disorders for SPC24 Gene
Additional Disease Information for SPC24
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for SPC24 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPC24 Gene
Publications for SPC24 Gene
- Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. (PMID: 15964272) Ahonen LJ … Gorbsky GJ (Current biology : CB 2005) 3 4 23
- Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore. (PMID: 15961401) Ciferri C … Musacchio A (The Journal of biological chemistry 2005) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. (PMID: 14738735) McCleland ML … Stukenberg PT (Current biology : CB 2004) 3 4
ExternalLinks
Products for SPC24 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for SPC24
- Origene Custom Protein Services for SPC24
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SPC24
- Browse OriGene Inhibitory RNA Products For SPC24
- OriGene qPCR primer pairs for SPC24
- OriGene CRISPR knockouts for SPC24
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SPC24
- Sino Biological Human cDNA Clone for SPC24
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SPC24
- Browse Sino Biological Assays
- Browse Antibodies
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SPC24
- Novus Biologicals proteins and lysates for SPC24
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SPC24
- Abcam proteins for SPC24
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SPC24 (AFLGC-SPC24)
- VectorBuilder Custom and pre-made DNA vectors for SPC24 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SPC24 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SPC24 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SPC24 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SPC24
- Addgene plasmids for SPC24
- antibodies-online: Show 8 available SPC24 Antibodies ranked by validation data
- Compare Top SPC24 Antibodies
- Quality Products:
- antibodies-online: Search results for available SPC24 related products ranked by validation data
- antibodies-online: Show 8 available SPC24 Proteins ranked by validation data
- Compare Top SPC24 Proteins
- Quality Products:
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SPC24
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SPC24
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SPC24
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SPC24
- Boster Bio Antibodies for SPC24
- Browse Boster Bio ELISA Kits
- Signalway ELISA kits for SPC24
Sources for SPC24 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB