Aliases for SPATA33 Gene
Aliases for SPATA33 Gene
External Ids for SPATA33 Gene
- HGNC: 26463
- Entrez Gene: 124045
- Ensembl: ENSG00000167523
- OMIM: 615409
- UniProtKB: Q96N06
Previous HGNC Symbols for SPATA33 Gene
- C16orf55
Previous GeneCards Identifiers for SPATA33 Gene
- GC16P089733
Summaries for SPATA33 Gene
GeneCards Summary for SPATA33 Gene
SPATA33 (Spermatogenesis Associated 33) is a Protein Coding gene.
Additional gene information for SPATA33 Gene
- Monarch Initiative
- Search for SPATA33 at DataMed
- Search for SPATA33 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA33 Gene
Genomics for SPATA33 Gene
GeneHancer (GH) Regulatory Elements for SPATA33 Gene
Promoters and enhancers for SPATA33 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SPATA33 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for SPATA33 Gene
Genomic Locations for SPATA33 Gene
- chr16:89,657,744-89,671,272
- (GRCh38/hg38)
- Size:
- 13,529 bases
- Orientation:
- Plus strand
- chr16:89,724,210-89,737,680
- (GRCh37/hg19)
Genomic View for SPATA33 Gene
Genes around SPATA33 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.3 by Ensembl
- 16q24.3 by Entrez Gene
- 16q24.3 by HGNC
SPATA33 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SPATA33 Gene
Proteins for SPATA33 Gene
-
Protein details for SPATA33 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96N06-SPT33_HUMAN
- Recommended name:
- Spermatogenesis-associated protein 33
- Protein Accession:
- Q96N06
- A8WFL2
- B4DZN8
Protein attributes for SPATA33 Gene
- Size:
- 139 amino acids
- Molecular mass:
- 15461 Da
- Quaternary structure:
- No Data Available
Protein Expression for SPATA33 Gene
Post-translational modifications for SPATA33 Gene
Other Protein References for SPATA33 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SPATA33
- Novus Biologicals Antibodies for SPATA33
- Invitrogen Antibodies for SPATA33
- Search GeneTex for Antibodies for SPATA33
-
Santa Cruz Biotechnology (SCBT) Antibodies for SPATA33
Protein Products
-
OriGene Purified Proteins for SPATA33
- Search Origene for MassSpec and Protein Over-expression Lysates for SPATA33
- Origene Custom Protein Services for SPATA33
- Search GeneTex for Proteins for SPATA33
Assay Products
No data available for DME Specific Peptides for SPATA33 Gene
Domains & Families for SPATA33 Gene
Gene Families for SPATA33 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for SPATA33 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for SPATA33 Gene
Function for SPATA33 Gene
Phenotypes From GWAS Catalog for SPATA33 Gene
Phenotypes for SPATA33 Gene
- GenomeRNAi human phenotypes for SPATA33:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPATA33
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SPATA33 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPATA33 gene
- Search ViGene Biosciences for SPATA33
CRISPR Products
-
OriGene CRISPR knockouts for SPATA33
- genomics-online: gRNA clones - Search results for available SPATA33 gene related products
- Applied Biological Materials CRISPR for SPATA33
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPATA33
- GenScript: Design CRISPR guide RNA sequences for SPATA33
miRNA Products
- Search ViGene Biosciences for SPATA33
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SPATA33
- Browse OriGene Inhibitory RNA Products For SPATA33
- genomics-online: shRNA clones - Search results for available SPATA33 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SPATA33 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for SPATA33
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPATA33
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SPATA33 gene related products
- orf clones - Search results for available SPATA33 gene related products
- Applied Biological Materials Clones for SPATA33
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SPATA33
-
ViGene Biosciences adenoviral particle packaged cDNA for SPATA33 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SPATA33 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPATA33 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA33 Gene
Localization for SPATA33 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SPATA33 Gene
- Cytoplasm, cytosol. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 4 |
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
Pathways & Interactions for SPATA33 Gene
No Data Available
Interacting Proteins for SPATA33 Gene
No data available for Pathways by source and SIGNOR curated interactions for SPATA33 Gene
Transcripts for SPATA33 Gene
mRNA/cDNA for SPATA33 Gene
- (6) REFSEQ mRNAs :
- (99) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for SPATA33
- genomics-online: gRNA clones - Search results for available SPATA33 gene related products
- Applied Biological Materials CRISPR for SPATA33
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPATA33
- GenScript: Design CRISPR guide RNA sequences for SPATA33
miRNA Products
- Search ViGene Biosciences for SPATA33
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SPATA33
- Browse OriGene Inhibitory RNA Products For SPATA33
- genomics-online: shRNA clones - Search results for available SPATA33 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SPATA33 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for SPATA33
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPATA33
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SPATA33 gene related products
- orf clones - Search results for available SPATA33 gene related products
- Applied Biological Materials Clones for SPATA33
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e | · | 10f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP11: |
Expression for SPATA33 Gene
mRNA differential expression in normal tissues according to GTEx for SPATA33 Gene
This gene is overexpressed in Testis (x13.8).
This gene is overexpressed in Testis (49.3) and Ovary (18.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SPATA33 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SPATA33 Gene:
SPATA33Evidence on tissue expression from TISSUES for SPATA33 Gene
- Spleen(3)
- Nervous system(3)
- Lung(2.9)
- Liver(2.8)
- Intestine(2.6)
- Kidney(2.6)
- Muscle(2.6)
- Heart(2.4)
Primer Products
-
OriGene qPCR primer pairs for SPATA33
-
OriGene qPCR primer pairs and template standards for SPATA33
- genomics-online: primer clones - Search results for available SPATA33 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPATA33 Gene
Orthologs for SPATA33 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SPATA33 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Spata33 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Spata33 33 |
|
||
| cow (Bos Taurus) |
Mammalia | SPATA33 33 |
|
||
| dog (Canis familiaris) |
Mammalia | SPATA33 34 |
|
OneToOne |
- Species where no ortholog for SPATA33 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for SPATA33 Gene
(1) SIMAP similar genes for SPATA33 Gene using alignment to 7 proteins:
No data available for Paralogs for SPATA33 Gene
Variants for SPATA33 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs369307331 | likely-benign, not specified | 89,657,569(+) | C/A | upstream_transcript_variant | |
| rs73262948 | benign, not specified | 89,657,619(+) | G/A/C/T | upstream_transcript_variant | |
| rs1000034231 | -- | 89,664,295(+) | G/A/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000251385 | -- | 89,662,835(+) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000335852 | -- | 89,659,132(+) | C/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2762221 | CNV | gain+loss | 21179565 |
| nsv1057351 | CNV | loss | 25217958 |
| nsv1063483 | CNV | gain | 25217958 |
| nsv1066382 | CNV | gain | 25217958 |
| nsv428331 | CNV | gain+loss | 18775914 |
| nsv457623 | CNV | gain | 19166990 |
| nsv482951 | CNV | loss | 15286789 |
| nsv509639 | CNV | insertion | 20534489 |
| nsv573739 | CNV | gain | 21841781 |
| nsv573743 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
88.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.32;
70.59% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SPATA33 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SPATA33
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA33 Gene
Disorders for SPATA33 Gene
Additional Disease Information for SPATA33
No disorders were found for SPATA33 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA33 Gene
Publications for SPATA33 Gene
- A novel testis-enriched gene Spata33 is expressed during spermatogenesis. (PMID: 23844118) Chen H … Zhou R (PloS one 2013) 2 3 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- Genome-wide association study in Han Chinese identifies three novel loci for human height. (PMID: 23456168) Hao Y … Gu D (Human genetics 2013) 3 58
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y … Sugano S (Genome research 2004) 3 58
Products for SPATA33 Gene
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- Custom Antibody ServicesOriGene Antibodies for SPATA33
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SPATA33
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- OriGene qPCR primer pairs and template standards for SPATA33
- OriGene qPCR primer pairs for SPATA33
- OriGene CRISPR knockouts for SPATA33
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Design CRISPR guide RNA sequences for SPATA33
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- Novus Biologicals Antibodies for SPATA33
- Novus Biologicals lysates and proteins for SPATA33
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
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- Browse ELISA Kits
- Browse Antibodies at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPATA33
- VectorBuilder custom plasmid, inducible vectors for SPATA33
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPATA33
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for SPATA33
- Search GeneTex for Proteins for SPATA33
- ViGene Biosciences adenoviral particle packaged cDNA for SPATA33 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SPATA33 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SPATA33 gene
- Search ViGene Biosciences for SPATA33
- Santa Cruz Biotechnology (SCBT) Antibodies for SPATA33
- Search Santa Cruz Biotechnology (SCBT) for SPATA33 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SPATA33
- Horizon Cell Lines for SPATA33
- genomics-online: cdna clones - Search results for available C16ORF55 gene related products
- orf clones - Search results for available C16ORF55 gene related products
- genomics-online: gRNA clones - Search results for available C16ORF55 gene related products
- genomics-online: primer clones - Search results for available C16ORF55 gene related products
- genomics-online: shRNA clones - Search results for available C16ORF55 gene related products
Sources for SPATA33 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems