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Aliases for SPATA31E1 Gene

Aliases for SPATA31E1 Gene

  • SPATA31 Subfamily E Member 1 2 3 5
  • Family With Sequence Similarity 75, Member E1 2 3
  • Protein FAM75E1 3 4
  • C9orf79 3 4
  • FAM75E1 3 4
  • Spermatogenesis-Associated Protein 31E1 3
  • Chromosome 9 Open Reading Frame 79 2
  • FAM75-Like Protein C9orf79 3
  • XXyac-YM21GA2.5 3

External Ids for SPATA31E1 Gene

Previous HGNC Symbols for SPATA31E1 Gene

  • C9orf79
  • FAM75E1

Previous GeneCards Identifiers for SPATA31E1 Gene

  • GC09P090499

Summaries for SPATA31E1 Gene

GeneCards Summary for SPATA31E1 Gene

SPATA31E1 (SPATA31 Subfamily E Member 1) is a Protein Coding gene. An important paralog of this gene is SPATA31A1.

UniProtKB/Swiss-Prot for SPATA31E1 Gene

  • May play a role in spermatogenesis.

Additional gene information for SPATA31E1 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31E1 Gene

Genomics for SPATA31E1 Gene

GeneHancer (GH) Regulatory Elements for SPATA31E1 Gene

Promoters and enhancers for SPATA31E1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I087882 Promoter/Enhancer 0.7 EPDnew dbSUPER 550.8 +0.0 32 0.1 PIR37243 SPATA31E1 PIR51268
GH09I087445 Enhancer 1.2 FANTOM5 Ensembl ENCODE 20.9 -436.9 -436923 0.6 PKNOX1 SUZ12 MAX E4F1 RFX5 ETS1 FOXK2 NFYB ZNF143 CREM SPATA31E1 GC09M087459 ENSG00000228373
GH09I087834 Enhancer 0.6 ENCODE 10.7 -48.4 -48355 0.2 CTCF IRF2 USF1 L3MBTL2 USF2 MNT CTBP1 FOXK2 ZNF143 NFE2 SPATA31E1 LOC649166 FBP2P1 NPAP1P7
GH09I087848 Enhancer 0.2 dbSUPER 11 -34.0 -33959 1.5 LOC497256 SPATA31E1 LOC649166 ENSG00000214888 PIR60572 ENSG00000233884
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SPATA31E1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SPATA31E1 Gene

Genomic Locations for SPATA31E1 Gene
6,074 bases
Plus strand

Genomic View for SPATA31E1 Gene

Genes around SPATA31E1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31E1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31E1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31E1 Gene

Proteins for SPATA31E1 Gene

  • Protein details for SPATA31E1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31E1
    Protein Accession:
    Secondary Accessions:
    • B2RPB1
    • Q5SQC9
    • Q8NA41
    • Q8ND27

    Protein attributes for SPATA31E1 Gene

    1445 amino acids
    Molecular mass:
    157136 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC04087.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD39098.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SPATA31E1 Gene

Post-translational modifications for SPATA31E1 Gene

  • Glycosylation at isoforms=408, isoforms=819, isoforms=906, and isoforms=1160
  • Modification sites at PhosphoSitePlus

Other Protein References for SPATA31E1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31E1 Gene

Domains & Families for SPATA31E1 Gene

Gene Families for SPATA31E1 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for SPATA31E1 Gene


Suggested Antigen Peptide Sequences for SPATA31E1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31E1: view

Function for SPATA31E1 Gene

Molecular function for SPATA31E1 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.
genes like me logo Genes that share phenotypes with SPATA31E1: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31E1 Gene

Localization for SPATA31E1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31E1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SPATA31E1 gene
Compartment Confidence
nucleus 2
plasma membrane 1
mitochondrion 1
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for SPATA31E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA31E1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SPATA31E1 Gene

Pathways & Interactions for SPATA31E1 Gene

SuperPathways for SPATA31E1 Gene

No Data Available

Interacting Proteins for SPATA31E1 Gene

Selected Interacting proteins: Q6ZUB1-S31E1_HUMAN for SPATA31E1 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SPATA31E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA31E1: view

No data available for Pathways by source and SIGNOR curated interactions for SPATA31E1 Gene

Drugs & Compounds for SPATA31E1 Gene

No Compound Related Data Available

Transcripts for SPATA31E1 Gene

mRNA/cDNA for SPATA31E1 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31E1 Gene

SPATA31 subfamily E, member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31E1 Gene

No ASD Table

Relevant External Links for SPATA31E1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA31E1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SPATA31E1 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31E1 Gene

This gene is overexpressed in Testis (x50.4).

Protein differential expression in normal tissues from HIPED for SPATA31E1 Gene

This gene is overexpressed in Heart (40.5) and Placenta (28.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31E1 Gene

Protein tissue co-expression partners for SPATA31E1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SPATA31E1 Gene:


SOURCE GeneReport for Unigene cluster for SPATA31E1 Gene:

genes like me logo Genes that share expression patterns with SPATA31E1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPATA31E1 Gene

Orthologs for SPATA31E1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31E1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC738069 33
  • 98.92 (n)
SPATA31E1 34
  • 98 (a)
(Canis familiaris)
Mammalia SPATA31E1 33 34
  • 59.51 (n)
(Bos Taurus)
Mammalia LOC101903343 33
  • 58.1 (n)
SPATA31E1 34
  • 35 (a)
(Mus musculus)
Mammalia 1700014D04Rik 34
  • 20 (a)
Species where no ortholog for SPATA31E1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31E1 Gene

Gene Tree for SPATA31E1 (if available)
Gene Tree for SPATA31E1 (if available)

Paralogs for SPATA31E1 Gene

genes like me logo Genes that share paralogs with SPATA31E1: view

Variants for SPATA31E1 Gene

Sequence variations from dbSNP and Humsavar for SPATA31E1 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000045342 -- 87,883,226(+) C/A intron_variant
rs1000376330 -- 87,889,058(+) T/C downstream_transcript_variant
rs1000652157 -- 87,881,868(+) A/G upstream_transcript_variant
rs1001115447 -- 87,881,094(+) G/A upstream_transcript_variant
rs1001482111 -- 87,884,769(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA31E1 Gene

Variant ID Type Subtype PubMed ID
nsv614788 CNV gain 21841781

Variation tolerance for SPATA31E1 Gene

Residual Variation Intolerance Score: 99% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 16.02; 97.50% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SPATA31E1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA31E1 Gene

Disorders for SPATA31E1 Gene

Additional Disease Information for SPATA31E1

No disorders were found for SPATA31E1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31E1 Gene

Publications for SPATA31E1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for SPATA31E1 Gene

Sources for SPATA31E1 Gene

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