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Aliases for SPATA31A5 Gene

Aliases for SPATA31A5 Gene

  • SPATA31 Subfamily A Member 5 2 3 5
  • Family With Sequence Similarity 75, Member A5 2 3
  • Protein FAM75A5 3 4
  • FAM75A5 3 4
  • Spermatogenesis-Associated Protein 31A5 3

External Ids for SPATA31A5 Gene

Previous HGNC Symbols for SPATA31A5 Gene

  • FAM75A5

Previous GeneCards Identifiers for SPATA31A5 Gene

  • GC09P041500

Summaries for SPATA31A5 Gene

GeneCards Summary for SPATA31A5 Gene

SPATA31A5 (SPATA31 Subfamily A Member 5) is a Protein Coding gene. An important paralog of this gene is SPATA31A7.

UniProtKB/Swiss-Prot for SPATA31A5 Gene

  • May play a role in spermatogenesis.

Additional gene information for SPATA31A5 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A5 Gene

Genomics for SPATA31A5 Gene

GeneHancer (GH) Regulatory Elements for SPATA31A5 Gene

Promoters and enhancers for SPATA31A5 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I060914 Promoter 0.5 EPDnew 550.8 +0.0 16 0.1 SPATA31A5 PIR42005
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SPATA31A5 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SPATA31A5 Gene

Genomic Locations for SPATA31A5 Gene
6,282 bases
Plus strand

Genomic View for SPATA31A5 Gene

Genes around SPATA31A5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31A5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A5 Gene

Proteins for SPATA31A5 Gene

  • Protein details for SPATA31A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31A5
    Protein Accession:

    Protein attributes for SPATA31A5 Gene

    1347 amino acids
    Molecular mass:
    148687 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A5 Gene

Post-translational modifications for SPATA31A5 Gene

No Post-translational modifications

Other Protein References for SPATA31A5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A5 Gene

Domains & Families for SPATA31A5 Gene

Gene Families for SPATA31A5 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for SPATA31A5 Gene


Suggested Antigen Peptide Sequences for SPATA31A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A5: view

Function for SPATA31A5 Gene

Molecular function for SPATA31A5 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A5 Gene

Localization for SPATA31A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A5 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SPATA31A5 gene
Compartment Confidence
plasma membrane 2

Gene Ontology (GO) - Cellular Components for SPATA31A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA31A5: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SPATA31A5 Gene

Pathways & Interactions for SPATA31A5 Gene

SuperPathways for SPATA31A5 Gene

No Data Available

Interacting Proteins for SPATA31A5 Gene

Gene Ontology (GO) - Biological Process for SPATA31A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA31A5: view

No data available for Pathways by source and SIGNOR curated interactions for SPATA31A5 Gene

Drugs & Compounds for SPATA31A5 Gene

No Compound Related Data Available

Transcripts for SPATA31A5 Gene

mRNA/cDNA for SPATA31A5 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A5 Gene

SPATA31 subfamily A, member 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A5 Gene

No ASD Table

Relevant External Links for SPATA31A5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA31A5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SPATA31A5 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31A5 Gene

This gene is overexpressed in Testis (x53.0).

NURSA nuclear receptor signaling pathways regulating expression of SPATA31A5 Gene:


SOURCE GeneReport for Unigene cluster for SPATA31A5 Gene:

genes like me logo Genes that share expression patterns with SPATA31A5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPATA31A5 Gene

Orthologs for SPATA31A5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31A5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC749550 33
  • 98.34 (n)
(Bos Taurus)
Mammalia SPATA31A3 33
  • 66.07 (n)
(Canis familiaris)
Mammalia SPATA31A3 33
  • 65.54 (n)
(Rattus norvegicus)
Mammalia Spata31a5 33
  • 59.25 (n)
(Mus musculus)
Mammalia Spata31 33
  • 58.67 (n)
Species where no ortholog for SPATA31A5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31A5 Gene

Gene Tree for SPATA31A5 (if available)
Gene Tree for SPATA31A5 (if available)

Paralogs for SPATA31A5 Gene

(11) SIMAP similar genes for SPATA31A5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPATA31A5: view

Variants for SPATA31A5 Gene

Sequence variations from dbSNP and Humsavar for SPATA31A5 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1001769542 -- 60,914,118(+) A/C upstream_transcript_variant
rs1035044715 -- 60,914,845(+) G/A intron_variant
rs1039609620 -- 60,915,343(+) GAGTGA/GA intron_variant
rs1047180411 -- 60,916,368(+) C/T intron_variant
rs17857234 -- 60,918,330(+) A/G coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA31A5 Gene

Variant ID Type Subtype PubMed ID
nsv972712 CNV duplication 23825009
nsv972697 CNV duplication 23825009
nsv972324 CNV duplication 23825009
nsv831565 CNV gain+loss 17160897
nsv482130 CNV gain 20164927
nsv1145210 CNV deletion 24896259
nsv1137635 CNV deletion 24896259
nsv1075628 CNV deletion 25765185
esv3891672 CNV gain+loss 25118596
dgv12693n54 CNV loss 21841781

Variation tolerance for SPATA31A5 Gene

Gene Damage Index Score: 0.03; 0.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SPATA31A5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA31A5 Gene

Disorders for SPATA31A5 Gene

Additional Disease Information for SPATA31A5

No disorders were found for SPATA31A5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A5 Gene

Publications for SPATA31A5 Gene

  1. The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y … Lee KF (Biochemical and biophysical research communications 2010) 2 3 58
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4 58

Products for SPATA31A5 Gene

Sources for SPATA31A5 Gene

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