Aliases for SOX1 Gene
External Ids for SOX1 Gene
Previous GeneCards Identifiers for SOX1 Gene
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOX1 Gene
SOX1 (SRY-Box Transcription Factor 1) is a Protein Coding gene. Diseases associated with SOX1 include Lambert-Eaton Myasthenic Syndrome and Cervical Adenocarcinoma. Among its related pathways are ERK Signaling and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and core promoter sequence-specific DNA binding. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot Summary for SOX1 Gene
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).