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Aliases for SOWAHD Gene

Aliases for SOWAHD Gene

  • Sosondowah Ankyrin Repeat Domain Family Member D 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 58 3 4
  • Protein Sosondowah Homolog D 3 4
  • Ankyrin Repeat Domain 58 2 3
  • ANKRD58 3 4
  • Ankyrin Repeat Domain-Containing Protein SOWAHD 3

External Ids for SOWAHD Gene

Previous HGNC Symbols for SOWAHD Gene

  • ANKRD58

Previous GeneCards Identifiers for SOWAHD Gene

  • GC0XP118893

Summaries for SOWAHD Gene

GeneCards Summary for SOWAHD Gene

SOWAHD (Sosondowah Ankyrin Repeat Domain Family Member D) is a Protein Coding gene. An important paralog of this gene is SOWAHC.

Additional gene information for SOWAHD Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SOWAHD Gene

Genomics for SOWAHD Gene

GeneHancer (GH) Regulatory Elements for SOWAHD Gene

Promoters and enhancers for SOWAHD Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI119753 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 557.7 -1.6 -1561 6.9 HDGF PKNOX1 ARID4B SIN3A DMAP1 IRF4 ZNF48 ZNF121 GLIS2 ZNF143 SOWAHD RNF113A NDUFA1 MIR766 EEF1A1P30 NKAPP1 UPF3B SEPT6 ZBTB33 PIR44405
GH0XI119762 Enhancer 0.6 ENCODE 0.8 +4.8 4773 1.3 USF1 CEBPB ZNF223 CEBPG ELF1 TEAD3 ZNF121 ZFHX2 ATF4 CEBPA NDUFA1 RNF113A UPF3B SLC25A43 SOWAHD GC0XM119788 GC0XM119789 SNORA69
GH0XI119775 Enhancer 0.7 Ensembl ENCODE 0.4 +17.1 17121 1.2 ZNF687 IKZF1 MLLT1 IKZF2 RUNX3 PRDM1 SPI1 RHOXF1-AS1 GC0XM119788 SNORA69 GC0XM119789 SOWAHD
GH0XI119760 Enhancer 0.3 ENCODE 0.8 +2.1 2060 0.2 IKZF1 NDUFA1 RNF113A SOWAHD GC0XM119788 GC0XM119789 SNORA69
GH0XI119769 Enhancer 0.6 FANTOM5 0.4 +10.9 10888 0.4 ZNF316 NFATC3 SP2 ASH1L EMSY RHOXF1 RNF113A NDUFA1 AKAP14 UPF3B SOWAHD GC0XM119788 SNORA69 GC0XM119789
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SOWAHD on UCSC Golden Path with GeneCards custom track

Genomic Locations for SOWAHD Gene

Genomic Locations for SOWAHD Gene
chrX:119,758,613-119,760,202
(GRCh38/hg38)
Size:
1,590 bases
Orientation:
Plus strand
chrX:118,892,576-118,894,165
(GRCh37/hg19)

Genomic View for SOWAHD Gene

Genes around SOWAHD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SOWAHD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SOWAHD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SOWAHD Gene

Proteins for SOWAHD Gene

  • Protein details for SOWAHD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJG2-SWAHD_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein SOWAHD
    Protein Accession:
    A6NJG2

    Protein attributes for SOWAHD Gene

    Size:
    315 amino acids
    Molecular mass:
    33803 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SOWAHD Gene

Post-translational modifications for SOWAHD Gene

No Post-translational modifications

Other Protein References for SOWAHD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SOWAHD Gene

Domains & Families for SOWAHD Gene

Gene Families for SOWAHD Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for SOWAHD Gene

Suggested Antigen Peptide Sequences for SOWAHD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJG2

UniProtKB/Swiss-Prot:

SWAHD_HUMAN :
  • Belongs to the SOWAH family.
Family:
  • Belongs to the SOWAH family.
genes like me logo Genes that share domains with SOWAHD: view

Function for SOWAHD Gene

Phenotypes for SOWAHD Gene

genes like me logo Genes that share phenotypes with SOWAHD: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SOWAHD Gene

Localization for SOWAHD Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SOWAHD gene
Compartment Confidence
mitochondrion 2
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SOWAHD Gene

Pathways & Interactions for SOWAHD Gene

SuperPathways for SOWAHD Gene

No Data Available

Interacting Proteins for SOWAHD Gene

Gene Ontology (GO) - Biological Process for SOWAHD Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SOWAHD Gene

Drugs & Compounds for SOWAHD Gene

No Compound Related Data Available

Transcripts for SOWAHD Gene

mRNA/cDNA for SOWAHD Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SOWAHD Gene

Sosondowah ankyrin repeat domain family member D:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SOWAHD Gene

No ASD Table

Relevant External Links for SOWAHD Gene

GeneLoc Exon Structure for
SOWAHD
ECgene alternative splicing isoforms for
SOWAHD

Expression for SOWAHD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SOWAHD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SOWAHD Gene

This gene is overexpressed in Whole Blood (x12.3), Spleen (x8.2), Testis (x5.2), and Small Intestine - Terminal Ileum (x4.4).

Protein differential expression in normal tissues from HIPED for SOWAHD Gene

This gene is overexpressed in Bone (40.3), Pancreas (10.4), and Testis (9.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SOWAHD Gene



Protein tissue co-expression partners for SOWAHD Gene

NURSA nuclear receptor signaling pathways regulating expression of SOWAHD Gene:

SOWAHD

SOURCE GeneReport for Unigene cluster for SOWAHD Gene:

Hs.355223
genes like me logo Genes that share expression patterns with SOWAHD: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SOWAHD Gene

Orthologs for SOWAHD Gene

This gene was present in the common ancestor of animals.

Orthologs for SOWAHD Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SOWAHD 33
  • 96.84 (n)
cow
(Bos Taurus)
Mammalia SOWAHD 33 34
  • 83.07 (n)
mouse
(Mus musculus)
Mammalia Sowahd 33 16 34
  • 70.85 (n)
rat
(Rattus norvegicus)
Mammalia Sowahd 33
  • 69.52 (n)
chicken
(Gallus gallus)
Aves SOWAHD 34
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SOWAHD 34
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SOWAHD 34
  • 25 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta sowah 34
  • 8 (a)
OneToMany
Species where no ortholog for SOWAHD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SOWAHD Gene

ENSEMBL:
Gene Tree for SOWAHD (if available)
TreeFam:
Gene Tree for SOWAHD (if available)

Paralogs for SOWAHD Gene

Paralogs for SOWAHD Gene

genes like me logo Genes that share paralogs with SOWAHD: view

Variants for SOWAHD Gene

Sequence variations from dbSNP and Humsavar for SOWAHD Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1002114254 -- 119,759,240(+) C/T coding_sequence_variant, synonymous_variant
rs1002710021 -- 119,757,511(+) T/C upstream_transcript_variant
rs1003288219 -- 119,759,595(+) C/T coding_sequence_variant, missense_variant
rs1005787973 -- 119,760,017(+) A/C 3_prime_UTR_variant
rs1006004447 -- 119,759,736(+) C/G 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for SOWAHD Gene

Variant ID Type Subtype PubMed ID
nsv7056 CNV deletion 18451855

Variation tolerance for SOWAHD Gene

Gene Damage Index Score: 0.67; 14.23% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SOWAHD Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SOWAHD

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOWAHD Gene

Disorders for SOWAHD Gene

Additional Disease Information for SOWAHD

No disorders were found for SOWAHD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SOWAHD Gene

Publications for SOWAHD Gene

  1. An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement. (PMID: 22234889) Maeso I … Garcia-Fernàndez J (Genome research 2012) 2 3 58
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58

Products for SOWAHD Gene

Sources for SOWAHD Gene

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