This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016] See more...

Aliases for SOS2 Gene

Aliases for SOS2 Gene

  • SOS Ras/Rho Guanine Nucleotide Exchange Factor 2 2 3 5
  • Son Of Sevenless Homolog 2 3 4
  • SOS-2 3 4
  • Son Of Sevenless (Drosophilia) Homolog 2 2
  • Son Of Sevenless Homolog 2 (Drosophila) 2
  • Guanine Nucleotide Releasing Factor 3
  • SOS2 5
  • NS9 3

External Ids for SOS2 Gene

Previous GeneCards Identifiers for SOS2 Gene

  • GC14M047905
  • GC14M044379
  • GC14M048573
  • GC14M048575
  • GC14M049654
  • GC14M050583
  • GC14M030709

Summaries for SOS2 Gene

Entrez Gene Summary for SOS2 Gene

  • This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016]

GeneCards Summary for SOS2 Gene

SOS2 (SOS Ras/Rho Guanine Nucleotide Exchange Factor 2) is a Protein Coding gene. Diseases associated with SOS2 include Noonan Syndrome 9 and Noonan Syndrome 1. Among its related pathways are G-protein signaling M-RAS regulation pathway and Toll-Like receptor Signaling Pathways. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is SOS1.

UniProtKB/Swiss-Prot Summary for SOS2 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SOS2 Gene

Genomics for SOS2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SOS2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J050229 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 +0.4 362 4.8 ZNF207 KLF9 POLR2A CEBPA ZIC2 ZBTB10 YY1 MXD4 NONO CEBPB SOS2 VCPKMT DMAC2L ENSG00000282885
GH14J050180 Promoter 0.3 EPDnew 261 +51.0 50988 0.1 SOS2 VCPKMT CDKL1 hsa-miR-5095-130 ENSG00000282885 RN7SL2 RN7SL3
GH14J050311 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 7.8 -80.5 -80523 3.4 BCLAF1 ZNF207 MYC ZNF600 ZNF592 POLR2A ZNF10 ZIC2 YY1 MXD4 DMAC2L L2HGDH lnc-CDKL1-2 VCPKMT ATL1 MAP4K5 SOS2
GH14J050334 Enhancer 1.1 ENCODE CraniofacialAtlas dbSUPER 10.4 -104.1 -104124 2.5 IKZF1 POLR2A ZIC2 FEZF1 BHLHE40 TAL1 ZNF316 PRDM6 ZNF189 MAFK DMAC2L CDKL1 ATL1 MAP4K5 SOS2 NONHSAG014911.2 L2HGDH piR-31470-165
GH14J050095 Enhancer 0.7 FANTOM5 ENCODE dbSUPER 10.4 +135.1 135053 2.3 SPI1 ARID3A VCPKMT RNU6-189P SOS2 DMAC2L RPL36AL ARF6 NEMF LINC01588 DNAAF2 piR-38344-041
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SOS2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SOS2

Top Transcription factor binding sites by QIAGEN in the SOS2 gene promoter:
  • aMEF-2
  • AREB6
  • GCNF
  • GCNF-1
  • GCNF-2
  • HSF2
  • IRF-7A
  • MEF-2A
  • Nkx6-1
  • TBP

Genomic Locations for SOS2 Gene

Latest Assembly
chr14:50,117,130-50,231,578
(GRCh38/hg38)
Size:
114,449 bases
Orientation:
Minus strand

Previous Assembly
chr14:50,583,848-50,698,296
(GRCh37/hg19 by Entrez Gene)
Size:
114,449 bases
Orientation:
Minus strand

chr14:50,583,847-50,698,276
(GRCh37/hg19 by Ensembl)
Size:
114,430 bases
Orientation:
Minus strand

Genomic View for SOS2 Gene

Genes around SOS2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SOS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SOS2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SOS2 Gene

Proteins for SOS2 Gene

  • Protein details for SOS2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q07890-SOS2_HUMAN
    Recommended name:
    Son of sevenless homolog 2
    Protein Accession:
    Q07890
    Secondary Accessions:
    • B7ZKT6
    • D3DSB4
    • Q15503
    • Q17RN1

    Protein attributes for SOS2 Gene

    Size:
    1332 amino acids
    Molecular mass:
    152979 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for SOS2 Gene

    Alternative splice isoforms for SOS2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SOS2 Gene

Post-translational modifications for SOS2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SOS2 Gene

No data available for DME Specific Peptides for SOS2 Gene

Domains & Families for SOS2 Gene

Gene Families for SOS2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for SOS2 Gene

Suggested Antigen Peptide Sequences for SOS2 Gene

GenScript: Design optimal peptide antigens:
  • Son of sevenless homolog 2 (Drosophila) (B7ZKT5_HUMAN)
  • Son of sevenless homolog 2 (SOS2_HUMAN)
genes like me logo Genes that share domains with SOS2: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SOS2 Gene

Function for SOS2 Gene

Molecular function for SOS2 Gene

UniProtKB/Swiss-Prot Function:
Promotes the exchange of Ras-bound GDP by GTP.
GENATLAS Biochemistry:
Drosophila son of sevenless homolog 2, regulator of Ras

Phenotypes From GWAS Catalog for SOS2 Gene

Gene Ontology (GO) - Molecular Function for SOS2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005085 guanyl-nucleotide exchange factor activity IEA --
GO:0005515 protein binding IPI 7629138
GO:0046982 protein heterodimerization activity IEA --
genes like me logo Genes that share ontologies with SOS2: view
genes like me logo Genes that share phenotypes with SOS2: view

Human Phenotype Ontology for SOS2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SOS2 Gene

MGI Knock Outs for SOS2:

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOS2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SOS2 Gene

Localization for SOS2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SOS2 gene
Compartment Confidence
cytosol 5
nucleus 3
plasma membrane 2
cytoskeleton 2
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SOS2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with SOS2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SOS2 Gene

Pathways & Interactions for SOS2 Gene

PathCards logo

SuperPathways for SOS2 Gene

SuperPathway Contained pathways
1 Common Cytokine Receptor Gamma-Chain Family Signaling Pathways
.42
.38
2 Regulation of lipid metabolism Insulin signaling-generic cascades
.59
.59
.51
.47
.44
.43
.35
.34
3 GPCR Pathway
.73
.73
.62
.59
.58
.58
.55
4 IL-2 Pathway
.59
.59
.54
.49
.48
.43
.34
5 Development Angiotensin activation of ERK
.73
.73
.68
.65
.54
.48
.40
genes like me logo Genes that share pathways with SOS2: view

Pathways by source for SOS2 Gene

76 GeneGo (Thomson Reuters) pathways for SOS2 Gene
  • Apoptosis and survival BAD phosphorylation
  • Apoptosis and survival NGF signaling pathway
  • Apoptosis and survival Role of CDK5 in neuronal death and survival
  • Cell adhesion PLAU signaling
  • Chemotaxis CXCR4 signaling pathway
73 Qiagen pathways for SOS2 Gene
  • Activation of cAMP-Dependent PKA
  • Aldosterone Signaling in Epithelial Cells
  • BAD Phosphorylation
  • BDNF Pathway
  • Beta-Adrenergic Signaling
1 GeneTex pathway for SOS2 Gene

SIGNOR curated interactions for SOS2 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for SOS2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001782 B cell homeostasis IEA --
GO:0002260 lymphocyte homeostasis IEA --
GO:0007186 G protein-coupled receptor signaling pathway TAS --
GO:0007264 small GTPase mediated signal transduction IEA --
GO:0033081 regulation of T cell differentiation in thymus IEA --
genes like me logo Genes that share ontologies with SOS2: view

Drugs & Compounds for SOS2 Gene

(5) Drugs for SOS2 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Guanosine triphosphate Experimental Pharma 0

(2) Additional Compounds for SOS2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SOS2: view

Transcripts for SOS2 Gene

mRNA/cDNA for SOS2 Gene

1 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOS2

Alternative Splicing Database (ASD) splice patterns (SP) for SOS2 Gene

No ASD Table

Relevant External Links for SOS2 Gene

GeneLoc Exon Structure for
SOS2

Expression for SOS2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SOS2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SOS2 Gene

This gene is overexpressed in Fetal Brain (13.6), Heart (11.4), Testis (9.6), and Spleen (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SOS2 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SOS2

SOURCE GeneReport for Unigene cluster for SOS2 Gene:

Hs.291533

Evidence on tissue expression from TISSUES for SOS2 Gene

  • Nervous system(4.5)
  • Kidney(2.2)
  • Skin(2.1)
  • Spleen(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for SOS2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cheek
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • forehead
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • outer ear
  • scalp
  • skull
  • tooth
Thorax:
  • aorta
  • breast
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • abdominal wall
  • liver
  • spleen
Pelvis:
  • pelvis
  • placenta
  • testicle
  • uterus
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • nail
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • hair
  • lymph node
  • lymph vessel
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with SOS2: view

Primer products for research

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SOS2 Gene

Orthologs for SOS2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SOS2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SOS2 29 30
  • 99.26 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia SOS2 29 30
  • 93.71 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia SOS2 29 30
  • 93.21 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia SOS2 30
  • 91 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia SOS2 30
  • 90 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Sos2 29 16 30
  • 88.58 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Sos2 29
  • 87.94 (n)
Chicken
(Gallus gallus)
Aves SOS2 29 30
  • 79.17 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia SOS2 30
  • 86 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia sos2 29
  • 75.93 (n)
Zebrafish
(Danio rerio)
Actinopterygii sos2 29 30
  • 67.68 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009180 29
  • 53.36 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Sos 30
  • 38 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea sos-1 30
  • 30 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CDC25 30
  • 16 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 51 (a)
OneToMany
Species where no ortholog for SOS2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SOS2 Gene

ENSEMBL:
Gene Tree for SOS2 (if available)
TreeFam:
Gene Tree for SOS2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SOS2: view image
Alliance of Genome Resources:
Additional Orthologs for SOS2

Paralogs for SOS2 Gene

(2) SIMAP similar genes for SOS2 Gene using alignment to 4 proteins:

  • SOS2_HUMAN
  • B7ZKT5_HUMAN
  • B7ZKT6_HUMAN
  • G3V5W3_HUMAN
genes like me logo Genes that share paralogs with SOS2: view

Variants for SOS2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SOS2 Gene

SNP ID Clinical significance and condition Chr 14 pos Variation AA Info Type
1001181 Uncertain Significance: Noonan syndrome 9 50,159,952(-) A/G
NM_006939.4(SOS2):c.1331T>C (p.Met444Thr)
MISSENSE
1001313 Uncertain Significance: Noonan syndrome 9 50,150,045(-) C/A
NM_006939.4(SOS2):c.2347G>T (p.Ala783Ser)
MISSENSE
1002804 Uncertain Significance: Noonan syndrome 9 50,199,811(-) A/C
NM_006939.4(SOS2):c.390T>G (p.Ile130Met)
MISSENSE
1003037 Uncertain Significance: Noonan syndrome 9 50,188,688(-) T/G
NM_006939.4(SOS2):c.523A>C (p.Met175Leu)
MISSENSE
1005668 Uncertain Significance: Noonan syndrome 9 50,199,743(-) C/T
NM_006939.4(SOS2):c.458G>A (p.Arg153Gln)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SOS2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SOS2 Gene

Variant ID Type Subtype PubMed ID
esv28926 CNV gain+loss 19812545
esv3581191 CNV loss 25503493
nsv1127380 CNV deletion 24896259
nsv1143609 CNV deletion 24896259
nsv564835 CNV gain 21841781
nsv564836 CNV loss 21841781

Variation tolerance for SOS2 Gene

Residual Variation Intolerance Score: 18.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.57; 56.04% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SOS2 Gene

Human Gene Mutation Database (HGMD)
SOS2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SOS2
Leiden Open Variation Database (LOVD)
SOS2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOS2 Gene

Disorders for SOS2 Gene

MalaCards: The human disease database

(20) MalaCards diseases for SOS2 Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

Disorder Aliases PubMed IDs
noonan syndrome 9
  • ns9
noonan syndrome 1
  • ns1
pseudo-turner syndrome
  • noonan syndrome
rasopathy
  • ras/mitogen-activated protein kinase syndrome
noonan syndrome-like disorder with loose anagen hair 2
  • nslh2
- elite association - COSMIC cancer census association via MalaCards
Search SOS2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

SOS2_HUMAN
  • Noonan syndrome 9 (NS9) [MIM:616559]: A form of Noonan syndrome, a disease characterized by short stature, facial dysmorphic features such as hypertelorism, a downward eyeslant and low-set posteriorly rotated ears, and a high incidence of congenital heart defects and hypertrophic cardiomyopathy. Other features can include a short neck with webbing or redundancy of skin, deafness, motor delay, variable intellectual deficits, multiple skeletal defects, cryptorchidism, and bleeding diathesis. Individuals with Noonan syndrome are at risk of juvenile myelomonocytic leukemia, a myeloproliferative disorder characterized by excessive production of myelomonocytic cells. {ECO:0000269 PubMed:25795793}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for SOS2

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SOS2: view

No data available for Genatlas for SOS2 Gene

Publications for SOS2 Gene

  1. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome. (PMID: 25795793) Yamamoto GL … Bertola DR (Journal of medical genetics 2015) 3 4 72
  2. Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci. (PMID: 17440948) Hamilton G … Lovestone S (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007) 3 22 40
  3. Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively. (PMID: 8276400) Webb GC … Bowtell DD (Genomics 1993) 2 3 22
  4. Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome. (PMID: 26173643) Cordeddu V … Tartaglia M (Human mutation 2015) 3 72
  5. Mutation of ARHGAP9 in patients with coronary spastic angina. (PMID: 19911011) Takefuji M … Kaibuchi K (Journal of human genetics 2010) 3 40

Products for SOS2 Gene

Sources for SOS2 Gene