Aliases for SOS2 Gene
External Ids for SOS2 Gene
Previous GeneCards Identifiers for SOS2 Gene
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016]
GeneCards Summary for SOS2 Gene
SOS2 (SOS Ras/Rho Guanine Nucleotide Exchange Factor 2) is a Protein Coding gene. Diseases associated with SOS2 include Noonan Syndrome 9 and Noonan Syndrome 1. Among its related pathways are Signaling by GPCR and Signaling by Robo receptor. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is SOS1.
UniProtKB/Swiss-Prot Summary for SOS2 Gene
Promotes the exchange of Ras-bound GDP by GTP.