Aliases for SOS2 Gene
External Ids for SOS2 Gene
Previous GeneCards Identifiers for SOS2 Gene
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016]
GeneCards Summary for SOS2 Gene
SOS2 (SOS Ras/Rho Guanine Nucleotide Exchange Factor 2) is a Protein Coding gene. Diseases associated with SOS2 include Noonan Syndrome 9 and Noonan Syndrome 1. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and GDNF-Family Ligands and Receptor Interactions. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is SOS1.
UniProtKB/Swiss-Prot Summary for SOS2 Gene
Promotes the exchange of Ras-bound GDP by GTP.