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The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same pr... See more...
Aliases for SOCS4 Gene
Aliases for SOCS4 Gene
External Ids for SOCS4 Gene
- HGNC: 19392
- Entrez Gene: 122809
- Ensembl: ENSG00000180008
- OMIM: 616337
- UniProtKB: Q8WXH5
Previous HGNC Symbols for SOCS4 Gene
- SOCS7
Previous GeneCards Identifiers for SOCS4 Gene
- GC14P052833
- GC18P068015
- GC18P067741
- GC18P066105
- GC14P053484
- GC14P054563
- GC14P055493
- GC14P035656
Summaries for SOCS4 Gene
-
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOCS4 Gene
SOCS4 (Suppressor Of Cytokine Signaling 4) is a Protein Coding gene. Among its related pathways are Type II diabetes mellitus and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase inhibitor activity. An important paralog of this gene is SOCS5.
UniProtKB/Swiss-Prot Summary for SOCS4 Gene
-
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SOCS4 Gene
Genomics for SOCS4 Gene
GeneHancer (GH) Regulatory Elements for SOCS4 Gene
Promoters and enhancers for SOCS4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SOCS4 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SOCS4 gene promoter:
-
- AML1a
- AREB6
- CREB
- Ik-1
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
- SEF-1 (1)
- STAT3
Genomic Locations for SOCS4 Gene
Genomic Locations for SOCS4 Gene
- chr14:55,027,126-55,049,489
- (GRCh38/hg38)
- Size:
- 22,364 bases
- Orientation:
- Plus strand
- chr14:55,493,844-55,516,207
- (GRCh37/hg19)
- Size:
- 22,364 bases
- Orientation:
- Plus strand
Genomic View for SOCS4 Gene
Genes around SOCS4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q22.3 by HGNC
- 14q22.3 by Entrez Gene
- 14q22.3 by Ensembl
SOCS4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SOCS4 Gene
Proteins for SOCS4 Gene
-
Protein details for SOCS4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WXH5-SOCS4_HUMAN
- Recommended name:
- Suppressor of cytokine signaling 4
- Protein Accession:
- Q8WXH5
Protein attributes for SOCS4 Gene
- Size:
- 440 amino acids
- Molecular mass:
- 50623 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for SOCS4 Gene
Other Protein References for SOCS4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents SOCS4 Antibody
- Atlas Antibodies Anti-SOCS4 Antibody
- Creative Diagnostics Anti-SOCS4 (aa 234-262) polyclonal antibody and Anti-SOCS4 (aa 426-439) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for SOCS4
- Novus Biologicals Antibodies for SOCS4
-
Abcam antibodies for SOCS4
- Invitrogen Antibodies for SOCS4 (AFLGC-SOCS4)
-
Biorbyt antibodies for SOCS4
-
Boster Bio Antibodies for SOCS4
-
Santa Cruz Biotechnology (SCBT) Antibodies for SOCS4
- Sino Biological Antibodies for SOCS4
Protein Products
-
OriGene Purified Proteins for SOCS4
- Search Origene for MassSpec and Protein Over-expression Lysates for SOCS4
- Origene Custom Protein Services for SOCS4
-
Abcam proteins for SOCS4
Assay Products
- antibodies-online: Show 3 available SOCS4 Elisa Kits ranked by validation data
- Compare Top SOCS4 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SOCS4 Gene
Domains & Families for SOCS4 Gene
Gene Families for SOCS4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SOCS4 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SOCS4 Gene
- GenScript: Design optimal peptide antigens:
-
- Suppressor of cytokine signaling 7 (SOCS4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WXH5UniProtKB/Swiss-Prot:
SOCS4_HUMAN :- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
- Domain:
-
- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Function for SOCS4 Gene
Molecular function for SOCS4 Gene
- UniProtKB/Swiss-Prot Function:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by EGF.
Phenotypes From GWAS Catalog for SOCS4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25814554 |
Phenotypes for SOCS4 Gene
- GenomeRNAi human phenotypes for SOCS4:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for SOCS4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SOCS4
- genomics-online: gRNA clones - Search for available SOCS4 gRNA products
- Overview of 123 available SOCS4 gene related products
- Applied Biological Materials (abm): CRISPR Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SOCS4 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SOCS4
miRNA for SOCS4 Gene
- miRTarBase miRNAs that target SOCS4
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SOCS4
- Browse OriGene Inhibitory RNA Products For SOCS4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOCS4
- genomics-online: shRNA clones - Search for available SOCS4 shRNA products
- Overview of 123 available SOCS4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SOCS4
- Addgene plasmids for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
- genomics-online: cdna clones - Search for available SOCS4 CDNA products
- Overview of 123 available SOCS4 gene related products
- orf clones - Search for available SOCS4 ORF products
- Overview of 123 available SOCS4 gene related products
- Applied Biological Materials (abm): Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SOCS4 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for SOCS4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SOCS4 Gene
Localization for SOCS4 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Cytosol (2)
- Nucleus (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SOCS4 Gene
Pathways & Interactions for SOCS4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL-2 Pathway |
Prolactin Signaling
.54
Growth Hormone Signaling
.49
|
IL-4 Pathway
.34
|
| 2 | Type II diabetes mellitus | ||
| 3 | PEDF Induced Signaling |
IL-6 Pathway
.61
|
STAT3 Pathway
.47
|
| 4 | TGF-Beta Pathway |
JAK-STAT Pathway
.57
|
SOCS Pathway
.40
|
| 5 | Regulation of lipid metabolism Insulin signaling-generic cascades | ||
Pathways by source for SOCS4 Gene
1 Sino Biological pathway for SOCS4 Gene
1 BioSystems pathway for SOCS4 Gene
4 KEGG pathways for SOCS4 Gene
1 R&D Systems pathway for SOCS4 Gene
7 Qiagen pathways for SOCS4 Gene
- Growth Hormone Signaling
- IL-4 Pathway
- IL-6 Pathway
- JAK-STAT Pathway
- Prolactin Signaling
UniProtKB/Swiss-Prot Q8WXH5-SOCS4_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for SOCS4 Gene
Selected Interacting proteins:
Q8WXH5-SOCS4_HUMAN
ENSP00000378855
for SOCS4 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SOCS4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity | IDA | 15590694 |
| GO:0009968 | negative regulation of signal transduction | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for SOCS4 Gene
Transcripts for SOCS4 Gene
mRNA/cDNA for SOCS4 Gene
- (2) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (121) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000339298 6667 bps (ENST00000339298.2)
- ENST00000395472 6779 bps (ENST00000395472.2)
- ENST00000553735 297 bps (ENST00000553735.1)
- ENST00000555846 6903 bps (ENST00000555846.1)
CRISPR Products
-
OriGene CRISPR knockouts for SOCS4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SOCS4
- genomics-online: gRNA clones - Search for available SOCS4 gRNA products
- Overview of 123 available SOCS4 gene related products
- Applied Biological Materials (abm): CRISPR Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SOCS4 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SOCS4
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SOCS4
- Browse OriGene Inhibitory RNA Products For SOCS4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOCS4
- genomics-online: shRNA clones - Search for available SOCS4 shRNA products
- Overview of 123 available SOCS4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SOCS4
- Addgene plasmids for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
- genomics-online: cdna clones - Search for available SOCS4 CDNA products
- Overview of 123 available SOCS4 gene related products
- orf clones - Search for available SOCS4 ORF products
- Overview of 123 available SOCS4 gene related products
- Applied Biological Materials (abm): Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SOCS4 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: | - |
Expression for SOCS4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
NURSA nuclear receptor signaling pathways regulating expression of SOCS4 Gene:
SOCS4SOURCE GeneReport for Unigene cluster for SOCS4 Gene:
Hs.744302Primer Products
-
OriGene qPCR primer pairs for SOCS4
-
OriGene qPCR primer pairs and template standards for SOCS4
- genomics-online: primer clones - Search for available SOCS4 Primer products
- Overview of 123 available SOCS4 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SOCS4 Gene
Orthologs for SOCS4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SOCS4 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SOCS4 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SOCS4 33 32 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Socs4 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Socs4 32 |
|
||
| chicken (Gallus gallus) |
Aves | SOCS4 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | SOCS4 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | socs4 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | socs9 32 |
|
||
| socs4 33 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Socs36E 33 34 |
|
OneToMany |
- Species where no ortholog for SOCS4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for SOCS4 Gene
- ENSEMBL:
- Gene Tree for SOCS4 (if available)
- TreeFam:
- Gene Tree for SOCS4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SOCS4: view image
Paralogs for SOCS4 Gene
Variants for SOCS4 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000072326 | -- | 55,026,825(+) | C/T | upstream_transcript_variant | |
| rs1000144229 | -- | 55,026,512(+) | G/T | upstream_transcript_variant | |
| rs1000300283 | -- | 55,033,169(+) | T/A | intron_variant | |
| rs1000321054 | -- | 55,028,433(+) | T/A | intron_variant | |
| rs1000399804 | -- | 55,039,668(+) | C/T | intron_variant |
Residual Variation Intolerance Score:
27.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.57;
12.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SOCS4 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOCS4 Gene
Disorders for SOCS4 Gene
Additional Disease Information for SOCS4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for SOCS4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SOCS4 Gene
Publications for SOCS4 Gene
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 43 56
- Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S … Kang D (Human immunology 2010) 3 43 56
- Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer. (PMID: 20433750) Sasi W … Mokbel K (BMC cancer 2010) 3 23 56
- Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. (PMID: 17997974) Bullock AN … Knapp S (Structure (London, England : 1993) 2007) 3 4 56
- Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. (PMID: 15590694) Kario E … Yarden Y (The Journal of biological chemistry 2005) 3 4 56
ExternalLinks
Products for SOCS4 Gene
- Custom Antibody ServicesOriGene Antibodies for SOCS4
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SOCS4
- Search Origene for MassSpec and Protein Over-expression Lysates for SOCS4
- Origene Custom Protein Services for SOCS4
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SOCS4
- Browse OriGene Inhibitory RNA Products For SOCS4
- OriGene qPCR primer pairs for SOCS4
- OriGene qPCR primer pairs and template standards for SOCS4
- OriGene CRISPR knockouts for SOCS4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SOCS4
- Sino Biological Human cDNA Clone for SOCS4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SOCS4
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SOCS4
- Novus Biologicals proteins and lysates for SOCS4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SOCS4
- Abcam proteins for SOCS4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SOCS4 (AFLGC-SOCS4)
- Addgene plasmids for SOCS4
- antibodies-online: Show 52 available SOCS4 Antibodies ranked by validation data
- Compare Top SOCS4 Antibodies
- antibodies-online: Show 3 available SOCS4 Elisa Kits ranked by validation data
- Compare Top SOCS4 Elisa Kits
- Quality Products:
- antibodies-online: Show 7 available SOCS4 Proteins ranked by validation data
- Compare Top SOCS4 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for SOCS4
- Search Santa Cruz Biotechnology (SCBT) for SOCS4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SOCS4
- Horizon Cell Lines for SOCS4
- genomics-online: cdna clones - Search for available SOCS4 CDNA products
- Overview of 123 available SOCS4 gene related products
- orf clones - Search for available SOCS4 ORF products
- Overview of 123 available SOCS4 gene related products
- genomics-online: gRNA clones - Search for available SOCS4 gRNA products
- Overview of 123 available SOCS4 gene related products
- genomics-online: primer clones - Search for available SOCS4 Primer products
- Overview of 123 available SOCS4 gene related products
- genomics-online: shRNA clones - Search for available SOCS4 shRNA products
- Overview of 123 available SOCS4 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SOCS4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOCS4
- Boster Bio Antibodies for SOCS4
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for SOCS4
Sources for SOCS4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
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