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The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same pr... See more...
Aliases for SOCS4 Gene
Aliases for SOCS4 Gene
External Ids for SOCS4 Gene
- HGNC: 19392
- Entrez Gene: 122809
- Ensembl: ENSG00000180008
- OMIM: 616337
- UniProtKB: Q8WXH5
Previous HGNC Symbols for SOCS4 Gene
- SOCS7
Previous GeneCards Identifiers for SOCS4 Gene
- GC14P052833
- GC18P068015
- GC18P067741
- GC18P066105
- GC14P053484
- GC14P054563
- GC14P055493
- GC14P035656
Summaries for SOCS4 Gene
-
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOCS4 Gene
SOCS4 (Suppressor Of Cytokine Signaling 4) is a Protein Coding gene. Diseases associated with SOCS4 include Borderline Glaucoma and Endometrial Stromal Sarcoma. Among its related pathways are IL-2 Pathway and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase inhibitor activity. An important paralog of this gene is SOCS5.
UniProtKB/Swiss-Prot Summary for SOCS4 Gene
-
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
Additional gene information for SOCS4 Gene
- HGNC(19392)
- Entrez Gene(122809)
- Ensembl(ENSG00000180008)
- OMIM(616337)
- UniProtKB(Q8WXH5)
- Open Targets Platform(ENSG00000180008)
- Search for SOCS4 at DataMed
- Search for SOCS4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SOCS4 Gene
Genomics for SOCS4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SOCS4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SOCS4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SOCS4
- Top Transcription factor binding sites by QIAGEN in the SOCS4 gene promoter:
-
- AML1a
- AREB6
- CREB
- Ik-1
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
- SEF-1 (1)
- STAT3
Genomic Locations for SOCS4 Gene
Genomic Locations for SOCS4 Gene
- chr14:55,027,131-55,049,489
- (GRCh38/hg38)
- Size:
- 22,359 bases
- Orientation:
- Plus strand
- chr14:55,493,844-55,516,207
- (GRCh37/hg19)
- Size:
- 22,364 bases
- Orientation:
- Plus strand
Genomic View for SOCS4 Gene
Genes around SOCS4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q22.3 by HGNC
- 14q22.3 by Entrez Gene
- 14q22.3 by Ensembl
SOCS4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SOCS4 Gene
Proteins for SOCS4 Gene
-
Protein details for SOCS4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WXH5-SOCS4_HUMAN
- Recommended name:
- Suppressor of cytokine signaling 4
- Protein Accession:
- Q8WXH5
Protein attributes for SOCS4 Gene
- Size:
- 440 amino acids
- Molecular mass:
- 50623 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for SOCS4 Gene
Other Protein References for SOCS4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents SOCS4 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SOCS4
- Novus Biologicals Antibodies for SOCS4
-
Abcam antibodies for SOCS4
- Invitrogen Antibodies for SOCS4 (AFLGC-SOCS4)
-
Biorbyt antibodies for SOCS4
-
Santa Cruz Biotechnology (SCBT) Antibodies for SOCS4
- Sino Biological Antibodies for SOCS4
Protein Products
-
OriGene Purified Proteins for SOCS4
- Search Origene for MassSpec and Protein Over-expression Lysates for SOCS4
- Origene Custom Protein Services for SOCS4
-
Abcam proteins for SOCS4
Assay Products
- antibodies-online: Show 3 available SOCS4 Elisa Kits ranked by validation data
- Compare Top SOCS4 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SOCS4 Gene
Domains & Families for SOCS4 Gene
Gene Families for SOCS4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SOCS4 Gene
- InterPro:
- Blocks:
-
- SOCS protein, C-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for SOCS4 Gene
- GenScript: Design optimal peptide antigens:
-
- Suppressor of cytokine signaling 7 (SOCS4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WXH5UniProtKB/Swiss-Prot:
SOCS4_HUMAN :- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
- Domain:
-
- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Function for SOCS4 Gene
Molecular function for SOCS4 Gene
- UniProtKB/Swiss-Prot Function:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by EGF.
Phenotypes From GWAS Catalog for SOCS4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25814554 |
| GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity | IBA | 21873635 |
Phenotypes for SOCS4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for SOCS4
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-
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miRNA for SOCS4 Gene
- miRTarBase miRNAs that target SOCS4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SOCS4
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Clone Products
- Applied Biological Materials (abm): Clones for SOCS4 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SOCS4
- Addgene plasmids for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
Cell Line Products
-
Horizon Cell Lines for SOCS4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SOCS4 Gene
Localization for SOCS4 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005942 | phosphatidylinositol 3-kinase complex | IBA | 21873635 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for SOCS4 Gene
Pathways & Interactions for SOCS4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL-2 Pathway |
Prolactin Signaling
.54
Growth Hormone Signaling
.49
|
IL-4 Pathway
.34
|
| 2 | Type II diabetes mellitus | ||
| 3 | PEDF Induced Signaling |
IL-6 Pathway
.61
|
STAT3 Pathway
.47
|
| 4 | TGF-Beta Pathway |
JAK-STAT Pathway
.57
|
SOCS Pathway
.41
|
| 5 | Regulation of lipid metabolism Insulin signaling-generic cascades | ||
Pathways by source for SOCS4 Gene
2 Sino Biological pathways for SOCS4 Gene
1 BioSystems pathway for SOCS4 Gene
4 KEGG pathways for SOCS4 Gene
7 Qiagen pathways for SOCS4 Gene
- Growth Hormone Signaling
- IL-4 Pathway
- IL-6 Pathway
- JAK-STAT Pathway
- Prolactin Signaling
UniProtKB/Swiss-Prot Q8WXH5-SOCS4_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for SOCS4 Gene
Selected Interacting proteins:
Q8WXH5-SOCS4_HUMAN
ENSP00000378855
for SOCS4 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SOCS4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity | IDA | 15590694 |
| GO:0009968 | negative regulation of signal transduction | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for SOCS4 Gene
Transcripts for SOCS4 Gene
mRNA/cDNA for SOCS4 Gene
- 2 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000339298 6667 nts (view in UCSC)
- ENST00000395472 6779 nts (view in UCSC)
- ENST00000553735 297 nts (view in UCSC)
- ENST00000555846 6903 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SOCS4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SOCS4
-
Santa Cruz Biotechnology (SCBT) CRISPR for SOCS4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SOCS4
- Browse OriGene Inhibitory RNA Products For SOCS4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOCS4
Clone Products
- Applied Biological Materials (abm): Clones for SOCS4 - Select products 50% OFF >
- * SOCS4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SOCS4
- Addgene plasmids for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: | - |
Relevant External Links for SOCS4 Gene
- GeneLoc Exon Structure for
- SOCS4
Expression for SOCS4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SOCS4
SOURCE GeneReport for Unigene cluster for SOCS4 Gene:
Hs.744302Evidence on tissue expression from TISSUES for SOCS4 Gene
- Liver(2.7)
- Spleen(2.6)
- Nervous system(2.5)
- Lymph node(2.4)
- Intestine(2.4)
- Bone marrow(2.4)
- Kidney(2.3)
- Blood(2.3)
- Heart(2.3)
- Lung(2.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for SOCS4
-
OriGene qPCR primer pairs and template standards for SOCS4
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SOCS4 Gene
Orthologs for SOCS4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SOCS4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SOCS4 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SOCS4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Socs4 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Socs4 30 |
|
||
| Chicken (Gallus gallus) |
Aves | SOCS4 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SOCS4 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | socs4 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | socs9 30 |
|
||
| socs4 31 |
|
OneToOne | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Socs36E 31 32 |
|
OneToMany |
- Species where no ortholog for SOCS4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SOCS4 Gene
- ENSEMBL:
- Gene Tree for SOCS4 (if available)
- TreeFam:
- Gene Tree for SOCS4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SOCS4: view image
Paralogs for SOCS4 Gene
Variants for SOCS4 Gene
Residual Variation Intolerance Score:
27.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.57;
12.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SOCS4 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOCS4 Gene
Disorders for SOCS4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| borderline glaucoma |
|
|
| endometrial stromal sarcoma |
|
|
Search SOCS4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SOCS4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SOCS4 Gene
Publications for SOCS4 Gene
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
- Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer. (PMID: 20433750) Sasi W … Mokbel K (BMC cancer 2010) 3 23
- Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S … Kang D (Human immunology 2010) 3 41
- Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. (PMID: 17997974) Bullock AN … Knapp S (Structure (London, England : 1993) 2007) 3 4
- Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. (PMID: 15590694) Kario E … Yarden Y (The Journal of biological chemistry 2005) 3 4
ExternalLinks
Products for SOCS4 Gene
- Custom Antibody ServicesOriGene Antibodies for SOCS4
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SOCS4
- Search Origene for MassSpec and Protein Over-expression Lysates for SOCS4
- Origene Custom Protein Services for SOCS4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SOCS4
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- OriGene qPCR primer pairs for SOCS4
- OriGene qPCR primer pairs and template standards for SOCS4
- OriGene CRISPR knockouts for SOCS4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SOCS4
- Sino Biological Human cDNA Clone for SOCS4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SOCS4
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SOCS4
- Novus Biologicals proteins and lysates for SOCS4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SOCS4
- Abcam proteins for SOCS4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SOCS4 (AFLGC-SOCS4)
- VectorBuilder Custom and pre-made DNA vectors for SOCS4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SOCS4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SOCS4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SOCS4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SOCS4
- Addgene plasmids for SOCS4
- antibodies-online: Show 52 available SOCS4 Antibodies ranked by validation data
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- antibodies-online: Show 3 available SOCS4 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 7 available SOCS4 Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for SOCS4
- Search Santa Cruz Biotechnology (SCBT) for SOCS4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SOCS4
- Horizon Cell Lines for SOCS4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SOCS4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SOCS4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SOCS4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SOCS4
- Biorbyt antibodies for SOCS4
Sources for SOCS4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB