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Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016] See more...
Aliases for SNX19 Gene
External Ids for SNX19 Gene
- HGNC: 21532
- NCBI Entrez Gene: 399979
- Ensembl: ENSG00000120451
- UniProtKB/Swiss-Prot: Q92543
Previous GeneCards Identifiers for SNX19 Gene
- GC11M132258
- GC11M130779
- GC11M130283
- GC11M130285
- GC11M130250
- GC11M126700
- GC11M130745
- GC11M130879
- GC11M130882
- GC11M130891
- GC11M130892
- GC11M130890
- GC11M130894
- GC11M130883
- GC11M130884
- GC11M130885
- GC11M130886
- GC11M130887
- GC11M130888
- GC11M130889
Summaries for SNX19 Gene
-
Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016]
GeneCards Summary for SNX19 Gene
SNX19 (Sorting Nexin 19) is a Protein Coding gene. Diseases associated with SNX19 include Spinocerebellar Ataxia, Autosomal Recessive 20 and Johanson-Blizzard Syndrome. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX14.
UniProtKB/Swiss-Prot Summary for SNX19 Gene
-
Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546). May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion (PubMed:24843546). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity).
Additional gene information for SNX19 Gene
- HGNC (21532)
- NCBI Entrez Gene (399979)
- Ensembl (ENSG00000120451)
- UniProtKB/Swiss-Prot (Q92543)
- Open Targets Platform(ENSG00000120451)
- Search for SNX19 at DataMed
- Search for SNX19 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SNX19 Gene
Genomics for SNX19 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SNX19 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SNX19 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SNX19
- Top Transcription factor binding sites by QIAGEN in the SNX19 gene promoter:
-
- AREB6
- Arnt
- c-Ets-1
- E47
- Hand1
- HOXA9
- HOXA9B
- Meis-1
- Meis-1a
- Nkx2-5
Genomic Locations for SNX19 Gene
Latest Assembly
- chr11:130,866,250-130,916,488
- (GRCh38/hg38)
- Size:
- 50,239 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:130,736,145-130,786,374
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 50,230 bases
- Orientation:
- Minus strand
- chr11:130,745,331-130,786,404
- (GRCh37/hg19 by Ensembl)
- Size:
- 41,074 bases
- Orientation:
- Minus strand
Genomic View for SNX19 Gene
Genes around SNX19 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q24.3-q25 by HGNC
- 11q24.3-q25 by Entrez Gene
- 11q25 by Ensembl
SNX19 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SNX19 Gene
Proteins for SNX19 Gene
-
Protein details for SNX19 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92543-SNX19_HUMAN
- Recommended name:
- Sorting nexin-19
- Protein Accession:
- Q92543
- E9PKB9
- Q8IV55
Protein attributes for SNX19 Gene
- Size:
- 992 amino acids
- Molecular mass:
- 108598 Da
- Quaternary structure:
-
- Interacts with PTPRN.
- SequenceCaution:
-
- Sequence=BAA13384.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Protein Expression for SNX19 Gene
Post-translational modifications for SNX19 Gene
Other Protein References for SNX19 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for SNX19
- Novus Biologicals Antibodies for SNX19
-
Abcam antibodies for SNX19
- Invitrogen Antibodies for SNX19 (AFLGC-SNX19)
-
Custom Antibody ServicesProSci Antibodies for SNX19
-
Santa Cruz Biotechnology (SCBT) Antibodies for SNX19
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for SNX19
- Origene Custom Protein Services for SNX19
- antibodies-online: Show 4 available SNX19 Proteins ranked by validation data
- Compare Top SNX19 Proteins
-
Quality Products:
-
Abcam proteins for SNX19
Assay products for research
No data available for DME Specific Peptides for SNX19 Gene
Domains & Families for SNX19 Gene
Gene Families for SNX19 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for SNX19 Gene
- InterPro:
- Blocks:
-
- Phox-like
- Sorting nexin, C-terminal
- PX-associated
- ProtoNet:
Suggested Antigen Peptide Sequences for SNX19 Gene
- GenScript: Design optimal peptide antigens:
-
- SNX19 protein (Q8IV55_HUMAN)
- Sorting nexin-19 (SNX19_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q92543UniProtKB/Swiss-Prot:
SNX19_HUMAN :- The PX domain mediates specific binding to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)).
- Belongs to the sorting nexin family.
- Domain:
-
- The PX domain mediates specific binding to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)).
- Family:
-
- Belongs to the sorting nexin family.
Function for SNX19 Gene
Molecular function for SNX19 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546). May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion (PubMed:24843546). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity).
Phenotypes From GWAS Catalog for SNX19 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16273344 |
| GO:0008289 | lipid binding | IEA | -- |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | IEA | -- |
| GO:0035091 | phosphatidylinositol binding | IEA | -- |
Phenotypes for SNX19 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SNX19 - Starting at $85 >
- * SNX19 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SNX19
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNX19
-
Santa Cruz Biotechnology (SCBT) CRISPR for SNX19
miRNA for SNX19 Gene
- miRTarBase miRNAs that target SNX19
-
- hsa-miR-376a-5p (MIRT001858)
- hsa-miR-27b-3p (MIRT046203)
- hsa-miR-1294 (MIRT484404)
- hsa-miR-4316 (MIRT484405)
- hsa-miR-7111-5p (MIRT484406)
- hsa-miR-6870-5p (MIRT484407)
- hsa-miR-5698 (MIRT484408)
- hsa-miR-4723-5p (MIRT484409)
- hsa-miR-625-5p (MIRT484410)
- hsa-miR-6825-5p (MIRT484411)
- hsa-miR-4725-3p (MIRT484412)
- hsa-miR-6780b-5p (MIRT484413)
- hsa-miR-4271 (MIRT484414)
- hsa-miR-6883-5p (MIRT484415)
- hsa-miR-6785-5p (MIRT484416)
- hsa-miR-4728-5p (MIRT484417)
- hsa-miR-149-3p (MIRT484418)
- hsa-miR-5196-5p (MIRT484419)
- hsa-miR-4747-5p (MIRT484420)
- hsa-miR-3202 (MIRT484421)
- hsa-miR-4787-5p (MIRT484422)
- hsa-miR-7515 (MIRT484423)
- hsa-miR-6794-5p (MIRT484424)
- hsa-miR-4716-3p (MIRT484425)
- hsa-miR-548aw (MIRT695987)
- hsa-miR-1468-3p (MIRT695988)
- hsa-miR-548x-5p (MIRT695989)
- hsa-miR-548g-5p (MIRT695990)
- hsa-miR-548f-5p (MIRT695991)
- hsa-miR-548aj-5p (MIRT695992)
- hsa-miR-4677-3p (MIRT695993)
- hsa-miR-4501 (MIRT695994)
- hsa-miR-548g-3p (MIRT695995)
- hsa-miR-3662 (MIRT695996)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SNX19
- Browse OriGene Inhibitory RNA Products For SNX19
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SNX19
Clone products for research
- Applied Biological Materials (abm): Clones for SNX19 - Starting at $45 >
- * SNX19 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SNX19
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNX19
Cell Lines for research
-
Horizon Cell Lines for SNX19
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNX19 Gene
Localization for SNX19 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SNX19 Gene
- Early endosome membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasmic vesicle membrane. Peripheral membrane protein. Cytoplasmic side.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| endosome | 3 |
| mitochondrion | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Mitochondria (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | 19877062 |
| GO:0005768 | endosome | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0030659 | cytoplasmic vesicle membrane | IEA | -- |
| GO:0031410 | cytoplasmic vesicle | IEA | -- |
Pathways & Interactions for SNX19 Gene
Interacting Proteins for SNX19 Gene
Selected Interacting proteins:
Q92543-SNX19_HUMAN
ENSP00000265909
for SNX19 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SNX19
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002062 | chondrocyte differentiation | IMP | 19877062 |
| GO:0006887 | exocytosis | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:0030073 | insulin secretion | IGI | 24843546 |
| GO:1990502 | dense core granule maturation | IGI | 24843546 |
No data available for Pathways by source and SIGNOR curated interactions for SNX19 Gene
Transcripts for SNX19 Gene
mRNA/cDNA for SNX19 Gene
- 12 REFSEQ mRNAs :
- 24 NCBI additional mRNA sequence :
- 13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000265909 15691 nts (view in UCSC)
- ENST00000426933 888 nts (view in UCSC)
- ENST00000524460 796 nts (view in UCSC)
- ENST00000526579 907 nts (view in UCSC)
- ENST00000527116 1323 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SNX19 - Starting at $85 >
- * SNX19 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SNX19
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNX19
-
Santa Cruz Biotechnology (SCBT) CRISPR for SNX19
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SNX19
- Browse OriGene Inhibitory RNA Products For SNX19
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SNX19
Clone products for research
- Applied Biological Materials (abm): Clones for SNX19 - Starting at $45 >
- * SNX19 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SNX19
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNX19
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for SNX19 Gene
- GeneLoc Exon Structure for
- SNX19
Expression for SNX19 Gene
This gene is overexpressed in Urinary Bladder (48.6), Oral epithelium (8.4), and Salivary gland (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SNX19 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNX19
SOURCE GeneReport for Unigene cluster for SNX19 Gene:
Hs.444024Evidence on tissue expression from TISSUES for SNX19 Gene
- Nervous system(4.8)
- Bone marrow(4.2)
Primer products for research
-
OriGene qPCR primer pairs for SNX19
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNX19 Gene
Orthologs for SNX19 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SNX19 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SNX19 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Snx19 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Snx19 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SNX19 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SNX19 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SNX19 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SNX19 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SNX19 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | snx19 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | snx19a 30 31 |
|
OneToMany | |
| snx19b 31 |
|
OneToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for SNX19 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SNX19 Gene
- ENSEMBL:
- Gene Tree for SNX19 (if available)
- TreeFam:
- Gene Tree for SNX19 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SNX19: view image
Paralogs for SNX19 Gene
(1) SIMAP similar genes for SNX19 Gene using alignment to 7 proteins:
- SNX19_HUMAN
- E7ERC7_HUMAN
- E9PJV7_HUMAN
- E9PKB9_HUMAN
- E9PLV3_HUMAN
- F5H5D1_HUMAN
- Q8IV55_HUMAN
Pseudogenes.org Pseudogenes for SNX19 Gene
Variants for SNX19 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SNX19 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs117260465 | Benign: not provided | 130,914,991(-) |
T/C NM_014758.2(SNX19):c.949A>G (p.Ser317Gly) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON | |
| rs142783173 | Benign: not provided | 130,880,697(-) |
G/A NM_014758.2(SNX19):c.2683C>T (p.Arg895Trp) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON | |
| rs144457394 | Likely Benign: not provided | 130,903,346(-) |
G/C NM_014758.2(SNX19):c.2482C>G (p.Leu828Val) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
| rs1592391767 | Likely Benign: not provided | 130,915,901(-) |
T/G NM_014758.2(SNX19):c.39A>C (p.Pro13=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON | |
| rs431825173 | Not Provided: not provided | 130,915,098(-) |
G/A NM_014758.2(SNX19):c.842C>T (p.Ala281Val) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1296n100 | CNV | gain | 25217958 |
| esv3309519 | CNV | mobile element insertion | 20981092 |
| esv3334474 | CNV | insertion | 20981092 |
| nsv1035733 | CNV | gain | 25217958 |
| nsv552 | CNV | deletion | 18451855 |
| nsv556572 | CNV | gain | 21841781 |
| nsv556574 | CNV | gain | 21841781 |
| nsv556575 | CNV | gain | 21841781 |
| nsv976000 | CNV | duplication | 23825009 |
| nsv976001 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
96% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
12.57;
94.46% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SNX19 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX19 Gene
Disorders for SNX19 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spinocerebellar ataxia, autosomal recessive 20 |
|
|
| johanson-blizzard syndrome |
|
|
| retinitis pigmentosa 42 |
|
|
| jacobsen syndrome |
|
|
Search SNX19 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SNX19
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SNX19 Gene
Publications for SNX19 Gene
- The IA-2 interactome. (PMID: 16273344) Hu YF … Notkins AL (Diabetologia 2005) 3 4 23
- Sorting nexin 19 regulates the number of dense core vesicles in pancreatic β-cells. (PMID: 24843546) Harashima S … Inagaki N (Journal of diabetes investigation 2012) 3 4
- Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke MM … Psaty BM (Stroke 2009) 3 41
- Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor. (PMID: 19877062) Kan A … Kawaguchi H (Arthritis and rheumatism 2009) 3 23
- The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. (PMID: 19730683) Landa I … Robledo M (PLoS genetics 2009) 3 41
ExternalLinks
Products for SNX19 Gene
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- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SNX19 (AFLGC-SNX19)
- VectorBuilder Custom and pre-made DNA vectors for SNX19 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SNX19 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SNX19 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SNX19 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SNX19
- antibodies-online: Show 4 available SNX19 Antibodies ranked by validation data
- Compare Top SNX19 Antibodies
- antibodies-online: Search results for available SNX19 related products ranked by validation data
- antibodies-online: Show 4 available SNX19 Proteins ranked by validation data
- Compare Top SNX19 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for SNX19
- Search Santa Cruz Biotechnology (SCBT) for SNX19 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SNX19
- Custom Antibody ServicesProSci Antibodies for SNX19
- Search for SNX19 Proteins at ProSci
- Horizon Cell Lines for SNX19
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNX19
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNX19
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SNX19
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SNX19
Sources for SNX19 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB