Aliases for SNTB2 Gene
External Ids for SNTB2 Gene
Previous HGNC Symbols for SNTB2 Gene
Previous GeneCards Identifiers for SNTB2 Gene
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNTB2 Gene
SNTB2 (Syntrophin Beta 2) is a Protein Coding gene. Diseases associated with SNTB2 include Muscular Dystrophy and Brugada Syndrome. Gene Ontology (GO) annotations related to this gene include calmodulin binding. An important paralog of this gene is SNTB1.
UniProtKB/Swiss-Prot Summary for SNTB2 Gene
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.