Aliases for SNTB1 Gene
External Ids for SNTB1 Gene
Previous HGNC Symbols for SNTB1 Gene
Previous GeneCards Identifiers for SNTB1 Gene
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNTB1 Gene
SNTB1 (Syntrophin Beta 1) is a Protein Coding gene. Diseases associated with SNTB1 include Muscular Dystrophy and Muscular Dystrophy, Duchenne Type. Among its related pathways are DREAM Repression and Dynorphin Expression and Muscular Dystrophies and Dystrophin-Glycoprotein Complex. Gene Ontology (GO) annotations related to this gene include actin binding and PDZ domain binding. An important paralog of this gene is SNTB2.
UniProtKB/Swiss-Prot Summary for SNTB1 Gene
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.