Aliases for SNRPD2 Gene
External Ids for SNRPD2 Gene
Previous HGNC Symbols for SNRPD2 Gene
Previous GeneCards Identifiers for SNRPD2 Gene
The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
GeneCards Summary for SNRPD2 Gene
SNRPD2 (Small Nuclear Ribonucleoprotein D2 Polypeptide) is a Protein Coding gene. Diseases associated with SNRPD2 include Basal Ganglia Cerebrovascular Disease and Spinal Muscular Atrophy. Among its related pathways are Transport of the SLBP independent Mature mRNA and mRNA Splicing - Minor Pathway.
UniProtKB/Swiss-Prot Summary for SNRPD2 Gene
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077).