Aliases for SNRPD2 Gene
Aliases for SNRPD2 Gene
External Ids for SNRPD2 Gene
- HGNC: 11159
- Entrez Gene: 6633
- Ensembl: ENSG00000125743
- OMIM: 601061
- UniProtKB: P62316
Previous HGNC Symbols for SNRPD2 Gene
- SNRPD1
Previous GeneCards Identifiers for SNRPD2 Gene
- GC19M046834
- GC19M046581
- GC19M050866
- GC19M050882
- GC19M046190
- GC19M042619
Summaries for SNRPD2 Gene
-
The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
GeneCards Summary for SNRPD2 Gene
SNRPD2 (Small Nuclear Ribonucleoprotein D2 Polypeptide) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Transport of the SLBP independent Mature mRNA.
UniProtKB/Swiss-Prot for SNRPD2 Gene
-
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
Additional gene information for SNRPD2 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNRPD2 Gene
Genomics for SNRPD2 Gene
GeneHancer (GH) Regulatory Elements for SNRPD2 Gene
Promoters and enhancers for SNRPD2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SNRPD2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SNRPD2 gene promoter:
-
- PPAR-gamma2
- PPAR-gamma1
- AP-2gamma
- AREB6
- GATA-1
- AML1a
- CUTL1
- CP2
- p300
- SREBP-1a
Regulatory Element Products
Genomic Locations for SNRPD2 Gene
Genomic Locations for SNRPD2 Gene
- chr19:45,687,454-45,692,569
- (GRCh38/hg38)
- Size:
- 5,116 bases
- Orientation:
- Minus strand
- chr19:46,190,712-46,195,827
- (GRCh37/hg19)
- Size:
- 5,116 bases
- Orientation:
- Minus strand
Genomic View for SNRPD2 Gene
Genes around SNRPD2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.32 by Entrez Gene
- 19q13.2-q13.3 by HGNC
- 19q13.32 by Ensembl
SNRPD2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SNRPD2 Gene
Proteins for SNRPD2 Gene
-
Protein details for SNRPD2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P62316-SMD2_HUMAN
- Recommended name:
- Small nuclear ribonucleoprotein Sm D2
- Protein Accession:
- P62316
- A8K797
- J3KPM5
- P43330
Protein attributes for SNRPD2 Gene
- Size:
- 118 amino acids
- Molecular mass:
- 13527 Da
- Quaternary structure:
-
- U1 snRNP is for instance composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
- Miscellaneous:
-
- In the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity.
Three dimensional structures from OCA and Proteopedia for SNRPD2 Gene
Protein Expression for SNRPD2 Gene
Post-translational modifications for SNRPD2 Gene
Other Protein References for SNRPD2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SNRPD2
- Novus Biologicals Antibodies for SNRPD2
- Invitrogen Antibodies for SNRPD2
- GeneTex SNRPD2 Antibody for SNRPD2
-
Boster Bio Antibodies for SNRPD2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for SNRPD2
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- ProSpec Recombinant Proteins for SNRPD2
- Search GeneTex for Proteins for SNRPD2
Assay Products
No data available for DME Specific Peptides for SNRPD2 Gene
Domains & Families for SNRPD2 Gene
Gene Families for SNRPD2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SNRPD2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SNRPD2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P62316- Family:
-
- Belongs to the snRNP core protein family.
Function for SNRPD2 Gene
Molecular function for SNRPD2 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
Phenotypes From GWAS Catalog for SNRPD2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0005515 | protein binding | IPI | 9417867 |
Phenotypes for SNRPD2 Gene
- GenomeRNAi human phenotypes for SNRPD2:
-
- Decreased shRNA abundance (Z-score < -2)
- Multipolar spindles
- G0/1 arrest
- Increased G1 DNA content
- Increased shRNA abundance (Z-score > 2)
- Decreased homologous recombination repair frequency
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased viability of wild-type and TP53 knockout cells, decreased TP53 protein expression ratio (wild-type / TP53 knockout cells)
- Reduced mammosphere formation
- Decreased shRNA abundance
- Decreased viability
- no effect
- Decreased influenza A virus infection
- Increased vaccinia virus (VACV) infection
- Decreased interferon-beta reporter expression
- Increased gamma-H2AX phosphorylation
- Decreased NF-kappaB reporter expression
- Decreased centriole number
- Increased viability
- FOXO1 nuclear localization
- Lamellipodia cells
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SNRPD2
-
CRISPR Products
-
OriGene CRISPR knockouts for SNRPD2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNRPD2
- genomics-online: gRNA clones - Search results for available SNRPD2 gene related products
- Applied Biological Materials CRISPR for SNRPD2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SNRPD2
- GenScript: Design CRISPR guide RNA sequences for SNRPD2
miRNA for SNRPD2 Gene
- miRTarBase miRNAs that target SNRPD2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SNRPD2
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- genomics-online: shRNA clones - Search results for available SNRPD2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SNRPD2
- VectorBuilder custom plasmid, inducible vectors for SNRPD2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SNRPD2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNRPD2
- genomics-online: cdna clones - Search results for available SNRPD2 gene related products
- orf clones - Search results for available SNRPD2 gene related products
- Applied Biological Materials Clones for SNRPD2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNRPD2 Gene
Localization for SNRPD2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SNRPD2 Gene
- Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 5 |
- Cytosol (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005681 | spliceosomal complex | TAS | 1701240 |
| GO:0005682 | U5 snRNP | IBA | -- |
| GO:0005685 | U1 snRNP | IDA | 21113136 |
Pathways & Interactions for SNRPD2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
.50
.41
|
| 2 | Transport of the SLBP independent Mature mRNA |
.55
|
|
| 3 | Gene Expression |
.48
|
|
| 4 | mRNA Splicing - Minor Pathway | ||
Pathways by source for SNRPD2 Gene
1 BioSystems pathway for SNRPD2 Gene
7 Reactome pathways for SNRPD2 Gene
1 KEGG pathway for SNRPD2 Gene
Interacting Proteins for SNRPD2 Gene
Selected Interacting proteins:
P62316-SMD2_HUMAN
ENSP00000342374
for SNRPD2 Gene via
IID
MINT
UniProtKB
STRING
GPS-Prot Interaction Network for SNRPD2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000245 | spliceosomal complex assembly | TAS | 7527560 |
| GO:0000387 | spliceosomal snRNP assembly | TAS | -- |
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0008380 | RNA splicing | TAS,IEA | 1701240 |
No data available for SIGNOR curated interactions for SNRPD2 Gene
Drugs & Compounds for SNRPD2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Dihydroartemisinin | Approved, Investigational | Pharma | Target, ligand | 100 |
Transcripts for SNRPD2 Gene
mRNA/cDNA for SNRPD2 Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (705) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000342669 901 bps (uc002pcw.4)
- ENST00000391932 615 bps (uc002pcv.4)
- ENST00000585392 379 bps (uc061abj.1)
- ENST00000587367 596 bps (uc061abk.1)
- ENST00000587579 290 bps (uc061abo.1)
Unigene Clusters for SNRPD2 Gene
- Small nuclear ribonucleoprotein D2 polypeptide 16.5kDa:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SNRPD2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNRPD2
- genomics-online: gRNA clones - Search results for available SNRPD2 gene related products
- Applied Biological Materials CRISPR for SNRPD2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SNRPD2
- GenScript: Design CRISPR guide RNA sequences for SNRPD2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SNRPD2
- Browse OriGene Inhibitory RNA Products For SNRPD2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SNRPD2
- genomics-online: shRNA clones - Search results for available SNRPD2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SNRPD2
- VectorBuilder custom plasmid, inducible vectors for SNRPD2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SNRPD2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNRPD2
- genomics-online: cdna clones - Search results for available SNRPD2 gene related products
- orf clones - Search results for available SNRPD2 gene related products
- Applied Biological Materials Clones for SNRPD2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||
| SP6: | - | - |
Expression for SNRPD2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Primary Oocyte Primary Follicle
-
Gonad
- Primary Oocyte Primary Follicle
- Endoderm (Gastrulation Derivatives)
This gene is overexpressed in Peripheral blood mononuclear cells (9.2) and Tlymphocyte (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SNRPD2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SNRPD2 Gene:
SNRPD2SOURCE GeneReport for Unigene cluster for SNRPD2 Gene:
Hs.515472Evidence on tissue expression from TISSUES for SNRPD2 Gene
- Lung(4.7)
- Nervous system(4)
- Skin(3.5)
- Liver(2.5)
- Blood(2.4)
- Lymph node(2.2)
- Muscle(2.2)
- Bone marrow(2.1)
- Intestine(2)
- Spleen(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for SNRPD2
-
OriGene qPCR primer pairs for SNRPD2
- genomics-online: primer clones - Search results for available SNRPD2 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNRPD2 Gene
Orthologs for SNRPD2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SNRPD2 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | SNRPD2 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SNRPD2 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Gm5449 34 |
|
OneToOne | |
| Snrpd2 16 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | SNRPD2 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SNRPD2 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Snrpd2 33 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | SNRPD2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | snrpd2 33 |
|
||
| Str.10758 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4271 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | snrpd2 34 33 |
|
OneToOne | |
| Dr.12513 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.778 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1249 35 |
|
|
|
| SmD2 34 33 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003936 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | snr-4 34 33 |
|
OneToOne | |
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D09284g 33 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGR277W 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SMD2 36 34 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G62840 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.3324 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os05g0314100 33 |
|
||
| Os.24812 33 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.2981 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| Cin.4211 33 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU03778 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | smd2 33 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4211 33 |
|
- Species where no ortholog for SNRPD2 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for SNRPD2 Gene
- ENSEMBL:
- Gene Tree for SNRPD2 (if available)
- TreeFam:
- Gene Tree for SNRPD2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SNRPD2: view image
Paralogs for SNRPD2 Gene
(2) SIMAP similar genes for SNRPD2 Gene using alignment to 3 proteins:
- SMD2_HUMAN
- K7EJB5_HUMAN
- K7ERG4_HUMAN
Pseudogenes.org Pseudogenes for SNRPD2 Gene
No data available for Paralogs for SNRPD2 Gene
Variants for SNRPD2 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000251542 | -- | 45,691,305(-) | A/G | intron_variant | |
| rs1000904139 | -- | 45,691,967(-) | T/G | 5_prime_UTR_variant | |
| rs1001526113 | -- | 45,690,002(-) | A/G | intron_variant | |
| rs1001883458 | -- | 45,689,969(-) | G/A | intron_variant | |
| rs1002165016 | -- | 45,690,371(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv960855 | CNV | duplication | 23825009 |
| esv3644509 | CNV | gain | 21293372 |
Residual Variation Intolerance Score:
43.1% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SNRPD2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SNRPD2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNRPD2 Gene
Disorders for SNRPD2 Gene
Additional Disease Information for SNRPD2
No disorders were found for SNRPD2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNRPD2 Gene
Publications for SNRPD2 Gene
- cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction. (PMID: 7527560) Lehmeier T … Lührmann R (Proceedings of the National Academy of Sciences of the United States of America 1994) 2 3 4 58
- Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. (PMID: 21516107) Leung AK … Li J (Nature 2011) 3 4 58
- An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. (PMID: 18984161) Chari A … Fischer U (Cell 2008) 3 4 58
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
- The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PMID: 15146077) Will CL … Lührmann R (RNA (New York, N.Y.) 2004) 3 4 58
Products for SNRPD2 Gene
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- ProSpec Recombinant Proteins for SNRPD2
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SNRPD2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 52 available SNRPD2 Antibodies ranked by validation data
- Compare Top SNRPD2 Antibodies
- antibodies-online: Search results for available SNRPD2 related products ranked by validation data
- antibodies-online: Search results for 14 available SNRPD2 Proteins ranked by validation data
- Compare Top SNRPD2 Proteins
- GeneTex SNRPD2 Antibody for SNRPD2
- Search GeneTex for Proteins for SNRPD2
- genomics-online: cdna clones - Search results for available SNRPD2 gene related products
- orf clones - Search results for available SNRPD2 gene related products
- genomics-online: gRNA clones - Search results for available SNRPD2 gene related products
- genomics-online: primer clones - Search results for available SNRPD2 gene related products
- genomics-online: shRNA clones - Search results for available SNRPD2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SNRPD2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SNRPD2
- GeneCopoeia miRNA 3'UTR Target clone products for SNRPD2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SNRPD2
- Boster Bio Antibodies for SNRPD2
- Browse Boster Bio ELISA Kits
Sources for SNRPD2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt