Aliases for SNRPB2 Gene
External Ids for SNRPB2 Gene
Previous GeneCards Identifiers for SNRPB2 Gene
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNRPB2 Gene
SNRPB2 (Small Nuclear Ribonucleoprotein Polypeptide B2) is a Protein Coding gene. Diseases associated with SNRPB2 include Systemic Lupus Erythematosus. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and snRNA binding. An important paralog of this gene is SNRPA.
UniProtKB/Swiss-Prot Summary for SNRPB2 Gene
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128).