External Ids for SNPH Gene
Previous GeneCards Identifiers for SNPH Gene
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
GeneCards Summary for SNPH Gene
SNPH (Syntaphilin) is a Protein Coding gene. Diseases associated with SNPH include Neuronopathy, Distal Hereditary Motor, Type Viib and Distal Hereditary Motor Neuronopathy Type 7. Gene Ontology (GO) annotations related to this gene include syntaxin-1 binding. An important paralog of this gene is SYBU.
UniProtKB/Swiss-Prot Summary for SNPH Gene
Inhibits SNARE complex formation by absorbing free syntaxin-1.