External Ids for SNPH Gene
Previous GeneCards Identifiers for SNPH Gene
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
GeneCards Summary for SNPH Gene
SNPH (Syntaphilin) is a Protein Coding gene. Diseases associated with SNPH include Communicating Hydrocephalus and Spinal Muscular Atrophy, Type Iv. Gene Ontology (GO) annotations related to this gene include syntaxin-1 binding. An important paralog of this gene is SYBU.
UniProtKB/Swiss-Prot Summary for SNPH Gene
Inhibits SNARE complex formation by absorbing free syntaxin-1.