Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83B, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83B, function in 2-prime-O-ribose methylation of rR... See more...

Aliases for SNORD83B Gene

Subcategory (RNA class) for SNORD83B Gene

snoRNA

Number of RNA Genes sources:

4 / 17

Aliases for SNORD83B Gene

  • Small Nucleolar RNA, C/D Box 83B 2 3 5
  • SNORD83B 2 5 170
  • RNA, U83B Small Nucleolar 2 3
  • U83B 2 3
  • U83b Small Nucleolar RNA 3
  • U83b SnoRNA 3
  • RF00593 168
  • SNODB88 177
  • RNU83B 3

External Ids for SNORD83B Gene

Previous HGNC Symbols for SNORD83B Gene

  • RNU83B

Previous GeneCards Identifiers for SNORD83B Gene

  • GC22M038041
  • GC22M038047
  • GC22M039709
  • GC22M022676
  • GC22M039334
  • GC22M039836
  • GC22M042774
  • GC22M042888
  • GC22M042945
  • GC22M044554
  • GC22M039848
  • GC22M039943
  • GC22M040632
  • GC22M041079
  • GC22M041477
  • GC22M041885
  • GC22M042314
  • GC22M042666

Summaries for SNORD83B Gene

Entrez Gene Summary for SNORD83B Gene

  • Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83B, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83B, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORD83B Gene

SNORD83B (Small Nucleolar RNA, C/D Box 83B) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD83B include Acute Hemorrhagic Encephalitis and Gastroduodenitis.

Rfam classification for SNORD83B Gene

Additional gene information for SNORD83B Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD83B Gene

Genomics for SNORD83B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORD83B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J039318 Enhancer 0.5 ENCODE 600.7 +0.4 380 0.2 POLR2A PATZ1 RBM22 SUPT5H RXRA ZNF24 GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 RPL3 lnc-SYNGR1-4 PDGFB
GH22J039312 Enhancer 0.5 ENCODE 600.7 +1.1 1149 0.4 POLR2A FOXA1 PATZ1 RBM22 SMAD5 SUPT5H SNORD83B piR-36713 lnc-PDGFB-4 RPL3 lnc-SYNGR1-4 PDGFB
GH22J039316 Enhancer 0.4 ENCODE 600.7 -1.0 -1030 0.2 PATZ1 POLR2A SMAD5 GLIS2 SNORD139 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 piR-57460-459 RPL3 PDGFB
GH22J039313 Enhancer 0.4 ENCODE 600.7 0.0 -30 0.2 POLR2A PATZ1 SUPT5H GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 RPL3 PDGFB
GH22J039317 Enhancer 0.4 ENCODE 600.7 -0.6 -610 0.2 CTCF PATZ1 POLR2A GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 piR-57460-459 RPL3 PDGFB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD83B on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD83B gene promoter:
  • AML1a
  • ATF6
  • Bach2
  • CUTL1
  • ER-alpha
  • STAT1
  • STAT1alpha
  • STAT1beta
  • STAT2

Genomic Locations for SNORD83B Gene

Genomic Locations for SNORD83B Gene
chr22:39,313,819-39,313,911
(GRCh38/hg38)
Size:
93 bases
Orientation:
Minus strand
chr22:39,709,824-39,709,916
(GRCh37/hg19)
Size:
93 bases
Orientation:
Minus strand

Genomic View for SNORD83B Gene

Genes around SNORD83B on UCSC Golden Path with GeneCards custom track
SNORD83B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORD83B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD83B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD83B Gene

Proteins for SNORD83B Gene

Post-translational modifications for SNORD83B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD83B Gene

Domains & Families for SNORD83B Gene

Gene Families for SNORD83B Gene

genes like me logo Genes that share domains with SNORD83B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD83B Gene

Function for SNORD83B Gene

Phenotypes From GWAS Catalog for SNORD83B Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD83B Gene

Localization for SNORD83B Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD83B gene
Compartment Confidence
nucleus 1
endosome 1

Gene Ontology (GO) - Cellular Components for SNORD83B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD83B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD83B Gene

Pathways & Interactions for SNORD83B Gene

PathCards logo

SuperPathways for SNORD83B Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD83B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD83B: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD83B Gene

Drugs & Compounds for SNORD83B Gene

No Compound Related Data Available

Transcripts for SNORD83B Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD83B Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000027315D_9606 snoRNA 93 7

HGNC: 17132,

RefSeq: NR_000028,

Ensembl: ENST00000386745 (view in UCSC) ,

Rfam: RF00593,

snoDB: SNODB88,

snOPY: Homo_sapiens300684,

ENA: AJ238852.1:4521..4613:ncRNA,

SNORD83B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD83B Gene

No ASD Table

Relevant External Links for SNORD83B Gene

GeneLoc Exon Structure for
SNORD83B

No data available for mRNA/cDNA for SNORD83B Gene

Expression for SNORD83B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD83B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD83B

genes like me logo Genes that share expression patterns with SNORD83B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD83B Gene

Orthologs for SNORD83B Gene

This gene was present in the common ancestor of mammals.

Orthologs for SNORD83B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia snoU83B 31
  • 100 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia snoU83B 31
  • 90 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Snord83b 31
  • 90 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia snoU83B 31
  • 90 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia snoU83B 31
  • 77 (a)
ManyToMany
Species where no ortholog for SNORD83B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for SNORD83B Gene

ENSEMBL:
Gene Tree for SNORD83B (if available)
TreeFam:
Gene Tree for SNORD83B (if available)

Paralogs for SNORD83B Gene

No data available for Paralogs for SNORD83B Gene

Variants for SNORD83B Gene

Additional dbSNP identifiers (rs#s) for SNORD83B Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORD83B Gene

Variant ID Type Subtype PubMed ID
nsv589033 CNV loss 21841781
nsv834198 CNV loss 17160897
nsv966110 CNV duplication 23825009

Additional Variant Information for SNORD83B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD83B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD83B Gene

Disorders for SNORD83B Gene

MalaCards: The human disease database

(2) MalaCards diseases for SNORD83B Gene - From: DISEASES

Disorder Aliases PubMed IDs
acute hemorrhagic encephalitis
gastroduodenitis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD83B

genes like me logo Genes that share disorders with SNORD83B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD83B Gene

Publications for SNORD83B Gene

  1. The intron-containing L3 ribosomal protein gene (RPL3): sequence analysis and identification of U43 and of two novel intronic small nucleolar RNAs. (PMID: 10684968) Duga S … Simonic T (Biochimica et biophysica acta 2000) 2 3
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3

Products for SNORD83B Gene

Sources for SNORD83B Gene