Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83A, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83A, function in 2-prime-O-ribose methylation of rR... See more...

Aliases for SNORD83A Gene

Subcategory (RNA class) for SNORD83A Gene

snoRNA

Number of RNA Genes sources:

4 / 17

Aliases for SNORD83A Gene

  • Small Nucleolar RNA, C/D Box 83A 2 3 5
  • SNORD83A 2 5 170
  • RNA, U83A Small Nucleolar 2 3
  • U83A 2 3
  • U83a Small Nucleolar RNA 3
  • U83a SnoRNA 3
  • SNODB219 177
  • RF00593 168
  • RNU83A 3

External Ids for SNORD83A Gene

Previous HGNC Symbols for SNORD83A Gene

  • RNU83A

Previous GeneCards Identifiers for SNORD83A Gene

  • GC22M038043
  • GC22M038044
  • GC22M039711
  • GC22M022677
  • GC22M039335
  • GC22M039837
  • GC22M042775
  • GC22M042889
  • GC22M042946
  • GC22M044555
  • GC22M039849
  • GC22M039944
  • GC22M040633
  • GC22M041080
  • GC22M041478
  • GC22M041886
  • GC22M042315
  • GC22M042667

Summaries for SNORD83A Gene

Entrez Gene Summary for SNORD83A Gene

  • Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83A, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83A, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORD83A Gene

SNORD83A (Small Nucleolar RNA, C/D Box 83A) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD83A include Acute Hemorrhagic Encephalitis and Exanthema Subitum.

Rfam classification for SNORD83A Gene

Additional gene information for SNORD83A Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD83A Gene

Genomics for SNORD83A Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORD83A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J039318 Enhancer 0.5 ENCODE 600.7 +1.8 1776 0.2 POLR2A PATZ1 RBM22 SUPT5H RXRA ZNF24 GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 RPL3 lnc-SYNGR1-4 PDGFB
GH22J039316 Enhancer 0.4 ENCODE 600.7 +0.4 366 0.2 PATZ1 POLR2A SMAD5 GLIS2 SNORD139 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 piR-57460-459 RPL3 PDGFB
GH22J039313 Enhancer 0.4 ENCODE 600.7 +1.4 1366 0.2 POLR2A PATZ1 SUPT5H GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 RPL3 PDGFB
GH22J039317 Enhancer 0.4 ENCODE 600.7 +0.8 786 0.2 CTCF PATZ1 POLR2A GLIS2 SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 piR-57460-459 RPL3 PDGFB
GH22J039314 Enhancer 0.3 ENCODE 600.7 +1.0 1046 0.2 CTCF POLR2A SNORD83A SNORD83B lnc-PDGFB-4 piR-36713 piR-57460-459 SYNGR1 PDGFB RPL3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD83A on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD83A gene promoter:
  • AML1a
  • ATF6
  • Bach2
  • CUTL1
  • ER-alpha
  • STAT1
  • STAT1alpha
  • STAT1beta
  • STAT2

Genomic Locations for SNORD83A Gene

Genomic Locations for SNORD83A Gene
chr22:39,315,213-39,315,307
(GRCh38/hg38)
Size:
95 bases
Orientation:
Minus strand
chr22:39,711,218-39,711,312
(GRCh37/hg19)
Size:
95 bases
Orientation:
Minus strand

Genomic View for SNORD83A Gene

Genes around SNORD83A on UCSC Golden Path with GeneCards custom track
SNORD83A in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORD83A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD83A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD83A Gene

Proteins for SNORD83A Gene

Post-translational modifications for SNORD83A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD83A Gene

Domains & Families for SNORD83A Gene

Gene Families for SNORD83A Gene

genes like me logo Genes that share domains with SNORD83A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD83A Gene

Function for SNORD83A Gene

Phenotypes From GWAS Catalog for SNORD83A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD83A Gene

Localization for SNORD83A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD83A gene
Compartment Confidence
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD83A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD83A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD83A Gene

Pathways & Interactions for SNORD83A Gene

PathCards logo

SuperPathways for SNORD83A Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD83A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD83A: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD83A Gene

Drugs & Compounds for SNORD83A Gene

No Compound Related Data Available

Transcripts for SNORD83A Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD83A Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000054DD16_9606 snoRNA 95 7

HGNC: 17131,

RefSeq: NR_000027,

Ensembl: ENST00000386747 (view in UCSC) ,

Rfam: RF00593,

snoDB: SNODB219,

snOPY: Homo_sapiens300685,

ENA: AJ238852.1:3125..3219:ncRNA,

SNORD83A in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD83A Gene

No ASD Table

Relevant External Links for SNORD83A Gene

GeneLoc Exon Structure for
SNORD83A

No data available for mRNA/cDNA for SNORD83A Gene

Expression for SNORD83A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD83A Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD83A

genes like me logo Genes that share expression patterns with SNORD83A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD83A Gene

Orthologs for SNORD83A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD83A Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia snoU83B 31
  • 100 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia snoU83B 31
  • 81 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia snoU83B 31 31
  • 76 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia snoU83B 31
  • 74 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia snoU83B 31
  • 65 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Gm22077 31
  • 61 (a)
OneToOne
Chicken
(Gallus gallus)
Aves snoU83B 31
  • 71 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia snoU83B 31
  • 68 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii snoU83B 31
  • 57 (a)
OneToOne
Species where no ortholog for SNORD83A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SNORD83A Gene

ENSEMBL:
Gene Tree for SNORD83A (if available)
TreeFam:
Gene Tree for SNORD83A (if available)

Paralogs for SNORD83A Gene

No data available for Paralogs for SNORD83A Gene

Variants for SNORD83A Gene

Additional dbSNP identifiers (rs#s) for SNORD83A Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORD83A Gene

Variant ID Type Subtype PubMed ID
nsv589033 CNV loss 21841781
nsv834198 CNV loss 17160897

Additional Variant Information for SNORD83A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD83A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD83A Gene

Disorders for SNORD83A Gene

MalaCards: The human disease database

(2) MalaCards diseases for SNORD83A Gene - From: DISEASES

Disorder Aliases PubMed IDs
acute hemorrhagic encephalitis
exanthema subitum
  • roseola infantum
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD83A

genes like me logo Genes that share disorders with SNORD83A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD83A Gene

Publications for SNORD83A Gene

  1. The intron-containing L3 ribosomal protein gene (RPL3): sequence analysis and identification of U43 and of two novel intronic small nucleolar RNAs. (PMID: 10684968) Duga S … Simonic T (Biochimica et biophysica acta 2000) 2 3
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3

Products for SNORD83A Gene

Sources for SNORD83A Gene