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Aliases for SNORD8 Gene

Subcategory (RNA class) for SNORD8 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD8 Gene

  • Small Nucleolar RNA, C/D Box 8 2 3 5
  • RNA, U6C Small Nucleolar 2 3
  • MgU6-53 3
  • RNU6C 3

External Ids for SNORD8 Gene

ORGUL Members for SNORD8 Gene

Previous HGNC Symbols for SNORD8 Gene

  • RNU6C

Previous GeneCards Identifiers for SNORD8 Gene

  • GC14M020937
  • GC14M021865
  • GC14M001985

Summaries for SNORD8 Gene

GeneCards Summary for SNORD8 Gene

SNORD8 (Small Nucleolar RNA, C/D Box 8) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD8 Gene

Genomics for SNORD8 Gene

GeneHancer (GH) Regulatory Elements for SNORD8 Gene

Promoters and enhancers for SNORD8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I021436 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.3 -40.0 -39972 2.5 PKNOX1 FOXA2 MLX ZFP64 ARID4B NEUROD1 SIN3A DMAP1 ZBTB7B YY1 CHD8 SUPT16H METTL3 SNORD8 UBA52P2 SNORD9 METTL17 ENSG00000257096 SALL2 TOX4
GH14I021454 Promoter/Enhancer 1.5 Ensembl ENCODE 11 -58.6 -58606 2.9 HDGF PKNOX1 CLOCK FOXA2 SMAD1 ARID4B SIN3A DMAP1 YY1 POLR2B CHD8 SUPT16H HNRNPC PNP METTL3 SNORD8 UBA52P2 SNORD9 ENSG00000257096 SALL2
GH14I021555 Enhancer 1.4 Ensembl ENCODE dbSUPER 10 -159.9 -159850 3.5 FOXA2 ARID4B SIN3A ZNF2 ZNF48 ETS1 YY1 SLC30A9 ZNF121 ARID2 SALL2 ENSG00000257096 UBA52P2 SNORD8 SNORD9 RPGRIP1 RBBP4P5
GH14I021307 Enhancer 1.2 Ensembl ENCODE 10.6 +88.8 88800 2.3 HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 RPGRIP1 HNRNPC SNORD9 SNORD8 UBA52P2 MRPS17P6 ENSG00000260830
GH14I021256 Enhancer 1 Ensembl ENCODE dbSUPER 11.2 +140.1 140085 2.4 PAF1 ZNF3 BACH1 CEBPG OSR2 NFIL3 SSRP1 PRDM6 POLR2A GLIS1 RPGRIP1 SNORD9 SNORD8 UBA52P2 TRAV8-5 GC14P021259 HNRNPC GC14P021210 GC14P021211
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD8 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD8 gene promoter:

Genomic Locations for SNORD8 Gene

Genomic Locations for SNORD8 Gene
chr14:21,397,292-21,397,401
(GRCh38/hg38)
Size:
110 bases
Orientation:
Minus strand
chr14:21,865,451-21,865,560
(GRCh37/hg19)

Genomic View for SNORD8 Gene

Genes around SNORD8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD8 Gene

Proteins for SNORD8 Gene

Post-translational modifications for SNORD8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD8 Gene

Domains & Families for SNORD8 Gene

Gene Families for SNORD8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD8 Gene

Function for SNORD8 Gene

Phenotypes From GWAS Catalog for SNORD8 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD8 Gene

Localization for SNORD8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD8 Gene

Pathways & Interactions for SNORD8 Gene

SuperPathways for SNORD8 Gene

No Data Available

Interacting Proteins for SNORD8 Gene

Gene Ontology (GO) - Biological Process for SNORD8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD8 Gene

Drugs & Compounds for SNORD8 Gene

No Compound Related Data Available

Transcripts for SNORD8 Gene

mRNA/cDNA for SNORD8 Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORD8 Gene

Small nucleolar RNA, C/D box 8:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD8 Gene

No ASD Table

Relevant External Links for SNORD8 Gene

GeneLoc Exon Structure for
SNORD8
ECgene alternative splicing isoforms for
SNORD8

Expression for SNORD8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD8 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD8 Gene:

SNORD8

SOURCE GeneReport for Unigene cluster for SNORD8 Gene:

Hs.680078
genes like me logo Genes that share expression patterns with SNORD8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD8 Gene

Orthologs for SNORD8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia snoU6-53 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia snoU6-53 34
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia snoU6-53 34
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snord8 34
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia snoU6-53 34
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia snoU6-53 34
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia snoU6-53 34
  • 71 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii snoU6-53 34 34 34
  • 69 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea snoU6-53 34 34
  • 61 (a)
ManyToMany
Species where no ortholog for SNORD8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD8 Gene

ENSEMBL:
Gene Tree for SNORD8 (if available)
TreeFam:
Gene Tree for SNORD8 (if available)

Paralogs for SNORD8 Gene

No data available for Paralogs for SNORD8 Gene

Variants for SNORD8 Gene

Sequence variations from dbSNP and Humsavar for SNORD8 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs879255360 uncertain-significance, not specified 21,397,934(-) G/A upstream_transcript_variant
rs1001524876 -- 21,397,194(-) G/A downstream_transcript_variant
rs1002178011 -- 21,396,857(-) G/A downstream_transcript_variant
rs1002390900 -- 21,397,657(-) A/G upstream_transcript_variant
rs1002772926 -- 21,398,643(-) C/T upstream_transcript_variant

Additional Variant Information for SNORD8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORD8 Gene

Disorders for SNORD8 Gene

Additional Disease Information for SNORD8

No disorders were found for SNORD8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD8 Gene

Publications for SNORD8 Gene

  1. Nucleolar factors direct the 2'-O-ribose methylation and pseudouridylation of U6 spliceosomal RNA. (PMID: 10490628) Ganot P … Kiss T (Molecular and cellular biology 1999) 2 3 58
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORD8 Gene

Sources for SNORD8 Gene

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