This gene encodes a spliceosomal small nuclear RNA that has orthologs in S. pombe and D. melanogaster. In S. pombe, this gene is required for site-specific 2'-O-methylation of U6 snRNA at position A41. While this is not an essential gene for S. pombe growth, loss of this gene's function may result in a slight decrease in mRNA splicing efficiency. [provided by RefSeq, Oct 2008] See more...

Aliases for SNORD7 Gene

Subcategory (RNA class) for SNORD7 Gene

snoRNA

Quality Score for this RNA gene is

15

Aliases for SNORD7 Gene

  • Small Nucleolar RNA, C/D Box 7 2 3 5
  • SNORD7 2 176
  • MgU6-47 3
  • RF00288 174
  • Z30 3

External Ids for SNORD7 Gene

Previous GeneCards Identifiers for SNORD7 Gene

  • GC17P030926
  • GC17P033901
  • GC17P030085
  • GC17P033905

Summaries for SNORD7 Gene

Entrez Gene Summary for SNORD7 Gene

  • This gene encodes a spliceosomal small nuclear RNA that has orthologs in S. pombe and D. melanogaster. In S. pombe, this gene is required for site-specific 2'-O-methylation of U6 snRNA at position A41. While this is not an essential gene for S. pombe growth, loss of this gene's function may result in a slight decrease in mRNA splicing efficiency. [provided by RefSeq, Oct 2008]

GeneCards Summary for SNORD7 Gene

SNORD7 (Small Nucleolar RNA, C/D Box 7) is an RNA Gene, and is affiliated with the snoRNA class.

Rfam classification for SNORD7 Gene

Additional gene information for SNORD7 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD7 Gene

Genomics for SNORD7 Gene

GeneHancer (GH) Regulatory Elements for SNORD7 Gene

Promoters and enhancers for SNORD7 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J035548 Enhancer 0.2 Ensembl 12.3 -25.3 -25256 0.4 SNORD7 PEX12 C17orf50 MMP28 AP2B1 TAF5LP1 piR-41689-007 ENSG00000267035 HSALNG0115956 SLFN14
GH17J035567 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas 0.4 -5.2 -5156 3 ZNF785 SIN3A SP1 ZBTB40 POLR2A USF2 ATF1 FOS CREB1 HCFC1 SNHG30 ENSG00000242660 LIG3 ZNF830 AP2B1 SLFN14 ENSG00000264622 PEX12 SLFN12 ENSG00000267592
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD7 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD7 gene promoter:
  • C/EBPalpha
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • Elk-1
  • FOXI1
  • Nkx2-2

Genomic Locations for SNORD7 Gene

Genomic Locations for SNORD7 Gene
chr17:35,573,657-35,573,753
(GRCh38/hg38)
Size:
97 bases
Orientation:
Plus strand
chr17:33,900,676-33,900,772
(GRCh37/hg19)
Size:
97 bases
Orientation:
Plus strand

Genomic View for SNORD7 Gene

Genes around SNORD7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD7 Gene

Proteins for SNORD7 Gene

Post-translational modifications for SNORD7 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD7 Gene

Domains & Families for SNORD7 Gene

Gene Families for SNORD7 Gene

genes like me logo Genes that share domains with SNORD7: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD7 Gene

Function for SNORD7 Gene

Phenotypes From GWAS Catalog for SNORD7 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD7 Gene

Localization for SNORD7 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD7 gene
Compartment Confidence
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD7: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD7 Gene

Pathways & Interactions for SNORD7 Gene

PathCards logo

SuperPathways for SNORD7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD7: view

No data available for Pathways by source and SIGNOR curated interactions for SNORD7 Gene

Drugs & Compounds for SNORD7 Gene

No Compound Related Data Available

Transcripts for SNORD7 Gene

mRNA/cDNA for SNORD7 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNACentral transcripts :
(1) ENA transcripts :
(1) Rfam transcripts :
(1) snOPY transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD7 Gene

No ASD Table

Relevant External Links for SNORD7 Gene

GeneLoc Exon Structure for
SNORD7
ECgene alternative splicing isoforms for
SNORD7

Expression for SNORD7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD7 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD7 Gene:

SNORD7
genes like me logo Genes that share expression patterns with SNORD7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD7 Gene

Orthologs for SNORD7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia snoZ30 33
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia snoZ30 33
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia snoZ30 33
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snord7 33
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia snoZ30 33
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia snoZ30 33
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves snoZ30 33
  • 77 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii snoZ30 33
  • 69 (a)
OneToOne
Species where no ortholog for SNORD7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD7 Gene

ENSEMBL:
Gene Tree for SNORD7 (if available)
TreeFam:
Gene Tree for SNORD7 (if available)

Paralogs for SNORD7 Gene

No data available for Paralogs for SNORD7 Gene

Variants for SNORD7 Gene

Sequence variations from dbSNP and Humsavar for SNORD7 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000021529 -- 35,573,224(+) G/C upstream_transcript_variant
rs1000257887 -- 35,571,970(+) C/T upstream_transcript_variant
rs1000458078 -- 35,572,862(+) G/C upstream_transcript_variant
rs1002098069 -- 35,571,794(+) T/C upstream_transcript_variant
rs1003438123 -- 35,572,380(+) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD7 Gene

Variant ID Type Subtype PubMed ID
esv3892999 CNV loss 25118596
nsv2038 CNV insertion 18451855

Additional Variant Information for SNORD7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD7 Gene

Disorders for SNORD7 Gene

Additional Disease Information for SNORD7

No disorders were found for SNORD7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD7 Gene

Publications for SNORD7 Gene

  1. The Schizosaccharomyces pombe mgU6-47 gene is required for 2'-O-methylation of U6 snRNA at A41. (PMID: 11842100) Zhou H … Qu LH (Nucleic acids research 2002) 2 3 56
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 56
  3. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 56
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 56

Products for SNORD7 Gene

Sources for SNORD7 Gene