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SNORD68 Gene(RNA Gene)

Small Nucleolar RNA, C/D Box 68

GCID:
GC16P089600
GIFtS:
16
Genes Participants
UDN Logo

Aliases for SNORD68 Gene

Subcategory (RNA class) for SNORD68 Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORD68 Gene

  • Small Nucleolar RNA, C/D Box 68 2 3 5
  • HBII-202 Small Nucleolar RNA 3
  • HBII-202 SnoRNA 3
  • HBII-202 3

External Ids for SNORD68 Gene

ORGUL Members for SNORD68 Gene

Previous GeneCards Identifiers for SNORD68 Gene

  • GC16P088157
  • GC16P089629
  • GC16P075323
  • GC16P089632
  • GC16P089636
  • GC16P089649
  • GC16P089658
  • GC16P089668
  • GC16P089563
  • GC16P089565
  • GC16P089568
  • GC16P089572
  • GC16P089581
  • GC16P089586
  • GC16P089591
  • GC16P089595

Summaries for SNORD68 Gene

GeneCards Summary for SNORD68 Gene

SNORD68 (Small Nucleolar RNA, C/D Box 68) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD68 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD68 Gene

Genomics for SNORD68 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for SNORD68 Gene

Promoters and enhancers for SNORD68 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH16J089558 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 700.2 +1.2 1196 7.9 CLOCK MLX DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC RPL13 SNORD68 GC16P089561 PIR32702 GC16P089560 ANKRD11 AFG3L1P TCF25 ENSG00000268218 ZC3H18
GH16J088809 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 37.8 -750.2 -750153 4.4 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF143 ZNF548 APRT ENSG00000259877 ANKRD11 SNORD68 LOC101927863 ZC3H18 GALNS ENSG00000268218 RPL13 ENSG00000260121
GH16J089993 Enhancer 1.5 Ensembl ENCODE dbSUPER 43.5 +433.8 433817 3.5 HDGF PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B SIN3A ZNF2 ZBTB7B PIR44838 AFG3L1P ENSG00000259877 ANKRD11 MC1R ACSF3 TCF25 LOC101927863 ENSG00000268218 SNORD68
GH16J089920 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23.6 +360.8 360844 4.2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 POLR2B FOS DEK PAF1 TUBB3 ENSG00000259006 ANKRD11 TCF25 LOC101927863 AFG3L1P SNORD68 ENSG00000268218 ACSF3 RPL13
GH16J088990 Enhancer 1.8 VISTA Ensembl ENCODE dbSUPER 27.7 -568.2 -568214 4.6 HNRNPUL1 PKNOX1 SMAD1 ARNT ZNF766 E2F8 ZNF143 ZNF263 REST ZNF592 ANKRD11 AFG3L1P SNORD68 ACSF3 ENSG00000268218 ZC3H18 RPL13 LOC101927863 TCF25 LOC100129697
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD68 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD68 gene promoter:
  • LCR-F1
  • RFX1
  • Olf-1
  • MEF-2A
  • aMEF-2
  • AML1a
  • Pax-5
  • POU2F1
  • POU2F1a

Genomic Locations for SNORD68 Gene

Genomic Locations for SNORD68 Gene
chr16:89,561,430-89,561,517
(GRCh38/hg38)
Size:
88 bases
Orientation:
Plus strand
chr16:89,627,838-89,627,925
(GRCh37/hg19)
Size:
88 bases
Orientation:
Plus strand

Genomic View for SNORD68 Gene

Genes around SNORD68 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD68 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD68 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORD68 Gene

Proteins for SNORD68 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORD68 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD68 Gene

Domains & Families for SNORD68 Gene

Gene Families for SNORD68 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD68: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD68 Gene

Function for SNORD68 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for SNORD68 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD68 Gene

Localization for SNORD68 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD68 Gene

Pathways & Interactions for SNORD68 Gene

SuperPathways for SNORD68 Gene

PathCards logo More details on SuperPathways for SNORD68
No Data Available

Interacting Proteins for SNORD68 Gene

Gene Ontology (GO) - Biological Process for SNORD68 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD68 Gene

Drugs & Compounds for SNORD68 Gene

Products:

  1. Drug

(2) Drugs for SNORD68 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Docetaxel Approved, Investigational Pharma Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes 2040
Thalidomide Approved, Investigational, Withdrawn Pharma Immunomodulatory agent,sedative drug,angiogenesis inhibitor, Immunomodulatory agents, TNF-alpha synthesis inhibitor 1195
genes like me logo Genes that share compounds with SNORD68: view

Transcripts for SNORD68 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for SNORD68 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD68 Gene

No ASD Table

Relevant External Links for SNORD68 Gene

GeneLoc Exon Structure for
SNORD68
ECgene alternative splicing isoforms for
SNORD68

Expression for SNORD68 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD68 Gene

mRNA expression in normal human tissues for SNORD68 Gene
mRNA expression by BioGPS for SNORD68 GenemRNA expression by GTEx for SNORD68 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD68 Gene:

SNORD68
genes like me logo Genes that share expression patterns with SNORD68: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD68 Gene

Orthologs for SNORD68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD68 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia snoMBII-202 34
  • 99 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia snoMBII-202 34
  • 85 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Snord68 34
  • 84 (a)
 OneToOne
oppossum
(Monodelphis domestica)
 Mammalia snoMBII-202 34
  • 81 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia snoMBII-202 34
  • 80 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia snoMBII-202 34
  • 80 (a)
 OneToOne
zebrafish
(Danio rerio)
 Actinopterygii snoMBII-202 34
  • 73 (a)
 OneToOne
Species where no ortholog for SNORD68 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD68 Gene

ENSEMBL:
Gene Tree for SNORD68 (if available)
TreeFam:
Gene Tree for SNORD68 (if available)

Paralogs for SNORD68 Gene

No data available for Paralogs for SNORD68 Gene

Variants for SNORD68 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for SNORD68 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1002510848 -- 89,561,881(+) G/A downstream_transcript_variant
rs1002601979 -- 89,559,636(+) G/C upstream_transcript_variant
rs1003342248 -- 89,561,229(+) G/A/T upstream_transcript_variant
rs1005493534 -- 89,559,710(+) C/G/T upstream_transcript_variant
rs1005877861 -- 89,560,544(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD68 Gene

Variant ID Type Subtype PubMed ID
nsv573738 CNV loss 21841781
nsv509639 CNV insertion 20534489
nsv482951 CNV loss 15286789
nsv471118 CNV gain 18288195
nsv428331 CNV gain+loss 18775914
nsv1066382 CNV gain 25217958
nsv1063483 CNV gain 25217958
esv3639588 CNV gain 21293372
esv3639587 CNV loss 21293372
esv2758670 CNV gain 17122850

Additional Variant Information for SNORD68 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD68

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD68 Gene

Disorders for SNORD68 Gene

Additional Disease Information for SNORD68

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for SNORD68 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD68 Gene

Publications for SNORD68 Gene

  1. RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse. (PMID: 11387227) Hüttenhofer A … Brosius J (The EMBO journal 2001) 2 3 58
  2. The numerous modified nucleotides in eukaryotic ribosomal RNA. (PMID: 2247610) Maden BE (Progress in nucleic acid research and molecular biology 1990) 2 3 58
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORD68 Gene

Sources for SNORD68 Gene

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