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Aliases for SNORD63 Gene

Subcategory (RNA class) for SNORD63 Gene


Quality Score for this RNA gene is


Aliases for SNORD63 Gene

  • Small Nucleolar RNA, C/D Box 63 2 3 5
  • RNA, U63 Small Nucleolar 2 3
  • SNORD63A 3
  • RNU63 3
  • U63 3

External Ids for SNORD63 Gene

Previous HGNC Symbols for SNORD63 Gene

  • RNU63

Previous GeneCards Identifiers for SNORD63 Gene

  • GC05M137926
  • GC05M133087
  • GC05M137897
  • GC05M137901

Summaries for SNORD63 Gene

GeneCards Summary for SNORD63 Gene

SNORD63 (Small Nucleolar RNA, C/D Box 63) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD63 include Ablepharon-Macrostomia Syndrome and Pulmonary Aspergilloma.

Additional gene information for SNORD63 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD63 Gene

Genomics for SNORD63 Gene

GeneHancer (GH) Regulatory Elements for SNORD63 Gene

Promoters and enhancers for SNORD63 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J138438 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 10.9 +121.8 121768 1.9 RB1 ZFP64 SIN3A ZEB1 ZNF335 ZNF23 GLIS2 ZNF366 BCLAF1 EGR2 REEP2 SNORD63B SNORD63 HSPA9 GC05P138442 GC05M138244
GH05J139341 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 9.2 -781.2 -781205 2.6 MLX DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF548 SP3 ZNF610 PAIP2 PURA KDM3B RPL7P19 ENSG00000232174 SLC23A1 MZB1 PROB1 MATR3 SNORA74A
GH05J138458 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.6 +101.7 101650 2 ELF3 PKNOX1 MLX ARID4B DNMT3B ZSCAN9 RARA SLC30A9 ATF7 IKZF2 GC05M138244 REEP2 SNORD63B SNORD63 HSPA9 LRRTM2 CDC25C FAM53C FAM13B ETF1
GH05J138461 Enhancer 1 FANTOM5 Ensembl dbSUPER 11.6 +99.7 99673 0.5 USF1 MAX NFYC USF2 PRDM10 PRDM1 NFKBIZ GC05M138244 REEP2 SNORD63 SNORD63B HSPA9 FAM53C ETF1 EGR1
GH05J138528 Enhancer 0.8 ENCODE 12.8 +32.0 31992 2 PKNOX1 FOXA2 NFIB NEUROD1 SIN3A ZNF121 SCRT2 RCOR1 CREM THAP11 SNORD63B SNORD63 HSPA9 ETF1 GC05M138528 GC05P138492
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD63 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD63 gene promoter:
  • CHOP-10
  • C/EBPalpha
  • POU2F1
  • POU2F1a
  • AML1a
  • POU3F2 (N-Oct-5a)
  • HOXA9
  • HOXA9B

Genomic Locations for SNORD63 Gene

Genomic Locations for SNORD63 Gene
68 bases
Minus strand
68 bases
Minus strand

Genomic View for SNORD63 Gene

Genes around SNORD63 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD63 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD63 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD63 Gene

Proteins for SNORD63 Gene

Post-translational modifications for SNORD63 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD63 Gene

Domains & Families for SNORD63 Gene

Gene Families for SNORD63 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD63: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD63 Gene

Function for SNORD63 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD63 Gene

Localization for SNORD63 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD63 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD63 Gene

Pathways & Interactions for SNORD63 Gene

SuperPathways for SNORD63 Gene

No Data Available

Interacting Proteins for SNORD63 Gene

Gene Ontology (GO) - Biological Process for SNORD63 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORD63 Gene

Drugs & Compounds for SNORD63 Gene

No Compound Related Data Available

Transcripts for SNORD63 Gene

mRNA/cDNA for SNORD63 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD63 Gene

No ASD Table

Relevant External Links for SNORD63 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORD63 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD63 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD63 Gene:

genes like me logo Genes that share expression patterns with SNORD63: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD63 Gene

Orthologs for SNORD63 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD63 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORD63 34
  • 100 (a)
(Mus musculus)
Mammalia Gm26109 34
  • 83 (a)
(Canis familiaris)
Mammalia SNORD63 34
  • 80 (a)
(Bos Taurus)
Mammalia SNORD63 34
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia SNORD63 34
  • 75 (a)
(Monodelphis domestica)
Mammalia SNORD63 34
  • 65 (a)
(Gallus gallus)
Aves SNORD63 34
  • 74 (a)
(Anolis carolinensis)
Reptilia SNORD63 34
  • 72 (a)
(Danio rerio)
Actinopterygii SNORD63 34
  • 66 (a)
Species where no ortholog for SNORD63 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD63 Gene

Gene Tree for SNORD63 (if available)
Gene Tree for SNORD63 (if available)

Paralogs for SNORD63 Gene

No data available for Paralogs for SNORD63 Gene

Variants for SNORD63 Gene

Sequence variations from dbSNP and Humsavar for SNORD63 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1002495043 -- 138,561,446(-) C/A upstream_transcript_variant
rs1002530522 -- 138,562,615(-) G/A upstream_transcript_variant
rs1002587916 -- 138,562,278(-) A/G upstream_transcript_variant
rs1004400214 -- 138,560,843(-) C/T downstream_transcript_variant
rs1005758071 -- 138,560,784(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD63 Gene

Variant ID Type Subtype PubMed ID
nsv599818 CNV loss 21841781

Additional Variant Information for SNORD63 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD63 Gene

Disorders for SNORD63 Gene

MalaCards: The human disease database

(2) MalaCards diseases for SNORD63 Gene - From: DISEASES

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD63

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SNORD63: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD63 Gene

Publications for SNORD63 Gene

  1. Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. (PMID: 19240791) Graubert TA … Walter MJ (PloS one 2009) 3 44 58
  2. A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. (PMID: 8962077) Tycowski KT … Steitz JA (Proceedings of the National Academy of Sciences of the United States of America 1996) 2 3 58
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORD63 Gene

Sources for SNORD63 Gene

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