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Aliases for SNORD58A Gene

Subcategory (RNA class) for SNORD58A Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORD58A Gene

  • Small Nucleolar RNA, C/D Box 58A 2 3 5
  • RNA, U58A Small Nuclear 2 3
  • RNU58A 3
  • U58a 3

External Ids for SNORD58A Gene

Previous HGNC Symbols for SNORD58A Gene

  • RNU58A

Previous GeneCards Identifiers for SNORD58A Gene

  • GC18M045282
  • GC18M045285
  • GC18M045289
  • GC18M045291
  • GC18M045297
  • GC18M045302
  • GC18M045308
  • GC18M047017
  • GC18M043871

Summaries for SNORD58A Gene

GeneCards Summary for SNORD58A Gene

SNORD58A (Small Nucleolar RNA, C/D Box 58A) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD58A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD58A Gene

Genomics for SNORD58A Gene

GeneHancer (GH) Regulatory Elements for SNORD58A Gene

Promoters and enhancers for SNORD58A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J049485 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 600.7 +1.5 1511 8.5 SP1 CC2D1A ZFX ELF3 NKRF POLR2A MLLT1 ZNF121 CEBPG GTF2F1 C18orf32 GC18M049521 GC18M049522 GC18M049523 GC18M049524 GC18M049525 GC18M049526 PIR54855 PIR54878 SNORD58A
GH18J049520 Enhancer 1 Ensembl ENCODE 11.1 -29.1 -29054 3.2 ZFX ZSCAN21 TRIM24 SP7 PRDM1 GLIS2 IKZF1 ZNF600 PRDM10 ZIC2 MBD1 LIPG RPL17-C18orf32 SNORD58A SNORD58C DYM C18orf32 ENSG00000265496 LINC02837 GC18M049549
GH18J049465 Enhancer 0.7 ENCODE 11.2 +25.9 25852 0.7 SP1 PRDM1 ZNF600 ZIC2 ZNF501 ZBTB44 ZNF205 OSR2 ZBTB17 ZNF189 SNORD58C RPL17-C18orf32 SNORD58A DYM PRR13P4
GH18J049527 Enhancer 0.7 Ensembl 11.2 -36.8 -36754 1.4 SMARCA4 HDAC1 ZNF316 SOX6 CTBP1 NFE2 MAFG ZNF335 DPF2 ZEB2 LIPG RPL17-C18orf32 SNORD58A SNORD58C DYM C18orf32 GC18M049549 LINC02837
GH18J049515 Enhancer 0.3 Ensembl 11.1 -24.7 -24654 0.8 MNT C18orf32 RPL17-C18orf32 SNORD58A SNORD58C LINC02837 GC18M049549
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD58A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD58A gene promoter:
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)
  • POU2F2B
  • POU2F2C
  • Sox9

Genomic Locations for SNORD58A Gene

Genomic Locations for SNORD58A Gene
chr18:49,491,283-49,491,347
(GRCh38/hg38)
Size:
65 bases
Orientation:
Minus strand
chr18:47,017,653-47,017,717
(GRCh37/hg19)
Size:
65 bases
Orientation:
Minus strand

Genomic View for SNORD58A Gene

Genes around SNORD58A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD58A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD58A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD58A Gene

Proteins for SNORD58A Gene

Post-translational modifications for SNORD58A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD58A Gene

Domains & Families for SNORD58A Gene

Gene Families for SNORD58A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD58A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD58A Gene

Function for SNORD58A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD58A Gene

Localization for SNORD58A Gene

Gene Ontology (GO) - Cellular Components for SNORD58A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD58A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORD58A Gene

Pathways & Interactions for SNORD58A Gene

PathCards logo

SuperPathways for SNORD58A Gene

No Data Available

Interacting Proteins for SNORD58A Gene

Gene Ontology (GO) - Biological Process for SNORD58A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD58A: view

No data available for Pathways by source and SIGNOR curated interactions for SNORD58A Gene

Drugs & Compounds for SNORD58A Gene

No Compound Related Data Available

Transcripts for SNORD58A Gene

mRNA/cDNA for SNORD58A Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD58A Gene

No ASD Table

Relevant External Links for SNORD58A Gene

GeneLoc Exon Structure for
SNORD58A
ECgene alternative splicing isoforms for
SNORD58A

Expression for SNORD58A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD58A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD58A Gene:

SNORD58A
genes like me logo Genes that share expression patterns with SNORD58A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD58A Gene

Orthologs for SNORD58A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD58A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD58 35
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23301 35
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD58 35
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORD58 35
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD58 35
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD58 35
  • 72 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORD58 35
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORD58 35
  • 79 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORD58 35
  • 68 (a)
ManyToMany
Species where no ortholog for SNORD58A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD58A Gene

ENSEMBL:
Gene Tree for SNORD58A (if available)
TreeFam:
Gene Tree for SNORD58A (if available)

Paralogs for SNORD58A Gene

No data available for Paralogs for SNORD58A Gene

Variants for SNORD58A Gene

Sequence variations from dbSNP and Humsavar for SNORD58A Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1000701955 -- 49,492,482(-) A/G upstream_transcript_variant
rs1000813008 -- 49,492,437(-) C/A/T upstream_transcript_variant
rs1001163459 -- 49,492,530(-) A/T upstream_transcript_variant
rs1001237844 -- 49,492,188(-) C/G/T upstream_transcript_variant
rs1001704327 -- 49,492,884(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD58A Gene

Variant ID Type Subtype PubMed ID
nsv1065279 CNV gain 25217958
nsv2294 CNV deletion 18451855
nsv978629 CNV duplication 23825009

Additional Variant Information for SNORD58A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD58A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD58A Gene

Disorders for SNORD58A Gene

Additional Disease Information for SNORD58A

No disorders were found for SNORD58A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD58A Gene

Publications for SNORD58A Gene

  1. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-László Z … Kiss T (Cell 1996) 2 3 58
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORD58A Gene

Sources for SNORD58A Gene

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