Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SNORD50A Gene

Subcategory (RNA class) for SNORD50A Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORD50A Gene

  • Small Nucleolar RNA, C/D Box 50A 2 3
  • RNA, U50 Small Nuclear 2 3
  • RNU50 3
  • U50 3

External Ids for SNORD50A Gene

ORGUL Members for SNORD50A Gene

Previous HGNC Symbols for SNORD50A Gene

  • RNU50

Previous GeneCards Identifiers for SNORD50A Gene

  • GC06M086448
  • GC06M086452
  • GC06M086455
  • GC06M086458
  • GC06M086459
  • GC06M086463
  • GC06M086389
  • GC06M086391
  • GC06M083612
  • GC06M086393

Summaries for SNORD50A Gene

Entrez Gene Summary for SNORD50A Gene

  • SNORD50A belongs to the C/D box class of small nucleolar RNAs (snoRNAs), which are thought to function as guide RNAs in the site-specific ribose methylation of preribosomal RNA (Kiss-Laszlo et al., 1996 [PubMed 8674114]).[supplied by OMIM, Nov 2009]

GeneCards Summary for SNORD50A Gene

SNORD50A (Small Nucleolar RNA, C/D Box 50A) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD50A include Pleuropneumonia and Shipyard Eye.

Additional gene information for SNORD50A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD50A Gene

Genomics for SNORD50A Gene

GeneHancer (GH) Regulatory Elements for SNORD50A Gene

Promoters and enhancers for SNORD50A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J085674 Promoter/Enhancer 1.6 Ensembl ENCODE 650.7 -0.3 -257 6.5 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SNHG5 SNORD50A SNORD50B GC06M085689 GC06M085688 GC06M085679 SYNCRIP LOC100127917 KRT18P64
GH06J085640 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 12.8 +34.1 34076 5.3 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 SYNCRIP SNHG5 LOC100127917 KRT18P64 SNORD50A SNX14 GC06P085634
GH06J085592 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.9 +83.4 83360 3 PKNOX1 FOXA2 SMAD1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B SNX14 SNHG5 SYNCRIP NT5E LOC100127917 KRT18P64 SNORD50A ENSG00000271793 GC06M085515
GH06J085614 Enhancer 0.6 UCNEbase 11.3 +63.1 63130 0.3 POLR2A HLF ENSG00000271793 SYNCRIP SNHG5 SNORD50A SNX14
GH06J085612 Promoter 0.6 EPDnew 11.3 +64.4 64440 0.1 POLR2A SYNCRIP SNORD50A SNHG5 ENSG00000271793 SNX14
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD50A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD50A gene promoter:
  • Pbx1a
  • POU2F1a
  • POU2F1
  • Egr-4
  • Egr-2
  • AP-2alpha
  • AP-2alphaA
  • AP-2beta
  • AP-2gamma
  • TFIID

Genomic Locations for SNORD50A Gene

Genomic Locations for SNORD50A Gene
chr6:85,677,294-85,677,368
(GRCh38/hg38)
Size:
75 bases
Orientation:
Minus strand
chr6:86,370,710-86,388,451
(GRCh37/hg19)
Size:
17,742 bases
Orientation:
Minus strand

Genomic View for SNORD50A Gene

Genes around SNORD50A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD50A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD50A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD50A Gene

Proteins for SNORD50A Gene

Post-translational modifications for SNORD50A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD50A Gene

Domains & Families for SNORD50A Gene

Gene Families for SNORD50A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD50A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD50A Gene

Function for SNORD50A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD50A Gene

Localization for SNORD50A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD50A Gene

Pathways & Interactions for SNORD50A Gene

SuperPathways for SNORD50A Gene

No Data Available

Interacting Proteins for SNORD50A Gene

Gene Ontology (GO) - Biological Process for SNORD50A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD50A Gene

Drugs & Compounds for SNORD50A Gene

No Compound Related Data Available

Transcripts for SNORD50A Gene

mRNA/cDNA for SNORD50A Gene

(1) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD50A Gene

No ASD Table

Relevant External Links for SNORD50A Gene

GeneLoc Exon Structure for
SNORD50A
ECgene alternative splicing isoforms for
SNORD50A

Expression for SNORD50A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD50A Gene:

SNORD50A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD50A Gene

Orthologs for SNORD50A Gene

No data available for Orthologs and Evolution for SNORD50A Gene

Paralogs for SNORD50A Gene

No data available for Paralogs for SNORD50A Gene

Variants for SNORD50A Gene

Sequence variations from dbSNP and Humsavar for SNORD50A Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000212406 -- 85,678,697(-) C/G/T upstream_transcript_variant
rs1001045088 -- 85,678,907(-) G/A/T upstream_transcript_variant
rs1001319671 -- 85,676,987(-) T/C downstream_transcript_variant
rs1001491918 -- 85,678,694(-) C/A upstream_transcript_variant
rs1001943933 -- 85,678,542(-) AT/ upstream_transcript_variant

Additional Variant Information for SNORD50A Gene

Human Gene Mutation Database (HGMD)
SNORD50A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD50A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORD50A Gene

Disorders for SNORD50A Gene

MalaCards: The human disease database

(3) MalaCards diseases for SNORD50A Gene - From: HGMD and DISEASES

Disorder Aliases PubMed IDs
pleuropneumonia
shipyard eye
  • ekc
opioid abuse
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD50A

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SNORD50A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD50A Gene

Publications for SNORD50A Gene

  1. Implication of snoRNA U50 in human breast cancer. (PMID: 19683667) Dong XY … Dong JT (Journal of genetics and genomics = Yi chuan xue bao 2009) 3 44 58
  2. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-László Z … Kiss T (Cell 1996) 2 3 58
  3. The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. (PMID: 26595770) Siprashvili Z … Khavari PA (Nature genetics 2016) 3 58
  4. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 58
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORD50A Gene

Sources for SNORD50A Gene

Content
Loading form....