Aliases for SNORD46 Gene

Subcategory (RNA class) for SNORD46 Gene

snoRNA

Number of RNA Genes sources:

4 / 17

Aliases for SNORD46 Gene

  • Small Nucleolar RNA, C/D Box 46 2 3 5
  • SNORD46 2 5 170
  • RNA, U46 Small Nuclear 2 3
  • RNA, U40 Small Nuclear 2 3
  • U40 2 3
  • U46 2 3
  • RNA, U40 Small Nucleolar 3
  • U40 Small Nucleolar RNA 3
  • U40 SnoRNA 3
  • SNODB444 177
  • RF00218 168
  • SNODB3 177
  • RNU40 3
  • RNU46 3

External Ids for SNORD46 Gene

Previous HGNC Symbols for SNORD46 Gene

  • RNU46
  • RNU40

Previous GeneCards Identifiers for SNORD46 Gene

  • GC01P045015
  • GC01P045242
  • GC01P043355
  • GC01P044777
  • GC01P044782
  • GC01P044833
  • GC01P044839
  • GC01P044838
  • GC01P044854
  • GC01P044787
  • GC01P044790
  • GC01P044796
  • GC01P044804
  • GC01P044805
  • GC01P044816
  • GC01P044823

Summaries for SNORD46 Gene

GeneCards Summary for SNORD46 Gene

SNORD46 (Small Nucleolar RNA, C/D Box 46) is an RNA Gene, and is affiliated with the snoRNA class.

Rfam classification for SNORD46 Gene

  • Small nucleolar RNA SNORD46

Additional gene information for SNORD46 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD46 Gene

Genomics for SNORD46 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORD46 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J044774 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +0.1 85 4.5 RNF2 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ZNF629 REST TFE3 IKZF1 RPS8 ENSG00000225721 SNORD38A SNORD38B SNORD46 SNORD55 lnc-BEST4-3 piR-31531 TOE1 GPBP1L1
GH01J044805 Promoter/Enhancer 2.1 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.3 +34.0 33961 10.7 RNF2 SP1 HNRNPL GATAD2A CTCF PRDM10 REST ZNF629 TFE3 ZNF512 TOE1 GPBP1L1 RPL7AP16 MUTYH RPS8 HECTD3 RPS15AP10 NASP TMEM69 ENSG00000225721
GH01J044746 Promoter 0.3 EPDnew 12 -30.1 -30096 0.1 KIF2C RPS8 ENSG00000225721 SNORD38A SNORD46 RNU5F-1 PLK3 TCTEX1D4 BTBD19 ARMH1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD46 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD46 gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • E47
  • Hand1
  • LyF-1
  • MyoD
  • Nkx2-5
  • SRF
  • SRF (504 AA)

Genomic Locations for SNORD46 Gene

Genomic Locations for SNORD46 Gene
chr1:44,776,490-44,776,593
(GRCh38/hg38)
Size:
104 bases
Orientation:
Plus strand
chr1:45,242,162-45,242,265
(GRCh37/hg19)
Size:
104 bases
Orientation:
Plus strand

Genomic View for SNORD46 Gene

Genes around SNORD46 on UCSC Golden Path with GeneCards custom track
SNORD46 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORD46 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD46 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD46 Gene

Proteins for SNORD46 Gene

Post-translational modifications for SNORD46 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD46 Gene

Domains & Families for SNORD46 Gene

Gene Families for SNORD46 Gene

genes like me logo Genes that share domains with SNORD46: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD46 Gene

Function for SNORD46 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD46 Gene

Localization for SNORD46 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD46 gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
cytosol 1

Gene Ontology (GO) - Cellular Components for SNORD46 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD46: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD46 Gene

Pathways & Interactions for SNORD46 Gene

PathCards logo

SuperPathways for SNORD46 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD46 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD46: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD46 Gene

Drugs & Compounds for SNORD46 Gene

No Compound Related Data Available

Transcripts for SNORD46 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD46 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000010A7C_9606 snoRNA 98 5

HGNC: 10186,

RefSeq: NR_000024,

snoDB: SNODB3,

snOPY: Homo_sapiens300662,

ENA: X96646.1:1..98:ncRNA,

URS0000650132_9606 snoRNA 104 3

Ensembl: ENST00000364043 (view in UCSC) ,

Rfam: RF00218,

snoDB: SNODB444,

URS0000295DAE_9606 snoRNA 100 2

Rfam: RF00218,

ENA: Z69628.1:1..100:ncRNA,

SNORD46 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for SNORD46 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD46 Gene

No ASD Table

Relevant External Links for SNORD46 Gene

GeneLoc Exon Structure for
SNORD46

Expression for SNORD46 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD46 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD46

genes like me logo Genes that share expression patterns with SNORD46: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD46 Gene

Orthologs for SNORD46 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD46 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SNORD46 31
  • 100 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Gm26330 31
  • 91 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia SNORD46 31
  • 90 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia SNORD46 31
  • 88 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia SNORD46 31
  • 66 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii SNORD46 31
  • 69 (a)
OneToMany
Species where no ortholog for SNORD46 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SNORD46 Gene

ENSEMBL:
Gene Tree for SNORD46 (if available)
TreeFam:
Gene Tree for SNORD46 (if available)

Paralogs for SNORD46 Gene

No data available for Paralogs for SNORD46 Gene

Variants for SNORD46 Gene

Additional dbSNP identifiers (rs#s) for SNORD46 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORD46 Gene

Variant ID Type Subtype PubMed ID
nsv461406 CNV loss 19166990
nsv546145 CNV loss 21841781
nsv998871 CNV loss 25217958

Additional Variant Information for SNORD46 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD46

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD46 Gene

Disorders for SNORD46 Gene

Additional Disease Information for SNORD46

No disorders were found for SNORD46 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD46 Gene

Publications for SNORD46 Gene

  1. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-László Z … Kiss T (Cell 1996) 2 3
  2. Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs. (PMID: 8764399) Nicoloso M … Bachellerie JP (Journal of molecular biology 1996) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3
  4. A study of the transfer of insulin-requiring diabetic patients from U-40 to U-100 Lente insulin. (PMID: 1606943) Abdulkadir J … Bekele G (Ethiopian medical journal 1992) 23

Products for SNORD46 Gene

Sources for SNORD46 Gene