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SNORD35A Gene(RNA Gene)

Small Nucleolar RNA, C/D Box 35A

GCID:
GC19P049575
GIFtS:
17
Genes Participants
UDN Logo

Aliases for SNORD35A Gene

Subcategory (RNA class) for SNORD35A Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORD35A Gene

  • Small Nucleolar RNA, C/D Box 35A 2 3 5
  • RNA, U35 Small Nucleolar 2 3
  • U35 Small Nucleolar RNA 3
  • U35 SnoRNA 3
  • RNU35A 3
  • RNU35 3
  • U35 3

External Ids for SNORD35A Gene

ORGUL Members for SNORD35A Gene

Previous HGNC Symbols for SNORD35A Gene

  • RNU35

Previous GeneCards Identifiers for SNORD35A Gene

  • GC19P054726
  • GC19P054733
  • GC19P054740
  • GC19P054747
  • GC19P054753
  • GC19P054760
  • GC19P054771
  • GC19P054784
  • GC19P049996
  • GC19P046371
  • GC19P049997
  • GC19P050012
  • GC19P050026
  • GC19P050045
  • GC19P049494
  • GC19P049501
  • GC19P049568
  • GC19P049508
  • GC19P049517
  • GC19P049523
  • GC19P049529
  • GC19P049538
  • GC19P049549
  • GC19P049554
  • GC19P049559

Summaries for SNORD35A Gene

GeneCards Summary for SNORD35A Gene

SNORD35A (Small Nucleolar RNA, C/D Box 35A) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD35A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD35A Gene

Genomics for SNORD35A Gene

GeneHancer (GH) Regulatory Elements for SNORD35A Gene

Promoters and enhancers for SNORD35A Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH19J049486 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 629.8 -1.3 -1321 8.1 HDGF SP1 ELF3 ZFX MNT SIX5 CBFA2T2 NKRF POLR2A MLLT1 SNORD35A RPL13A GC19P049531 GC19P049571 GC19P049581 GC19P049586 GC19P049587 PIR58998 PIR54526 SNORD32A
GH19J050022 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 57.4 +533.7 533700 4.7 SP1 ZFX ELF3 MNT SIX5 NKRF POLR2A MLLT1 CEBPG RERE ZNF473 VRK3 POLD1 SNORD35A ALDH16A1 SNORD35B NUP62 PTOV1-AS2 IRF3 SIGLEC16
GH19J048871 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 43.6 -615.4 -615423 8.2 MTA3 SP1 CC2D1A ELF3 ZKSCAN8 CBFA2T2 ZNF148 NKRF POLR2A MLLT1 GC19M048876 PPP1R15A SNRNP70 PRR12 GRWD1 PTOV1-AS2 IRF3 SNORD35A SNORD35B PIH1D1
GH19J048644 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 47.5 -845.4 -845374 3.2 SP1 CC2D1A CTCF SIX5 ZNF148 MLLT1 ZSCAN21 CDC5L BACH1 MCM2 CA11 GRWD1 SNORD35A NOP53-AS1 ALDH16A1 SNORD35B PRR12 NOP53 RPS11 SNRNP70
GH19J049874 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 39.9 +385.6 385559 5.2 SP1 CC2D1A ZFX ELF3 MNT SIX5 CBFA2T2 ZNF148 NKRF POLR2A PNKP AKT1S1 TBC1D17 PIR46791 NUP62 POLD1 PTOV1-AS2 SNORD35A IRF3 ALDH16A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD35A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD35A gene promoter:
  • AP-4
  • c-Ets-1
  • E47
  • GATA-1
  • NF-1
  • NF-1/L
  • STAT3
  • Tal-1beta
  • TBP

Genomic Locations for SNORD35A Gene

Genomic Locations for SNORD35A Gene
chr19:49,491,175-49,491,260
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand
chr19:49,994,432-49,994,517
(GRCh37/hg19)
Size:
86 bases
Orientation:
Plus strand

Genomic View for SNORD35A Gene

Genes around SNORD35A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD35A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD35A Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORD35A Gene

Proteins for SNORD35A Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORD35A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD35A Gene

Domains & Families for SNORD35A Gene

Gene Families for SNORD35A Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD35A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD35A Gene

Function for SNORD35A Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for SNORD35A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD35A Gene

Localization for SNORD35A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD35A gene
Compartment Confidence
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SNORD35A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD35A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD35A Gene

Pathways & Interactions for SNORD35A Gene

GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
PathCards logo

SuperPathways for SNORD35A Gene

No Data Available

Interacting Proteins for SNORD35A Gene

Gene Ontology (GO) - Biological Process for SNORD35A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD35A: view

No data available for Pathways by source and SIGNOR curated interactions for SNORD35A Gene

Drugs & Compounds for SNORD35A Gene

Products:

  1. Drug
GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
No Compound Related Data Available

Transcripts for SNORD35A Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for SNORD35A Gene

(55) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD35A Gene

No ASD Table

Relevant External Links for SNORD35A Gene

GeneLoc Exon Structure for
SNORD35A
ECgene alternative splicing isoforms for
SNORD35A

Expression for SNORD35A Gene

Products:

  1. Primer
  2. Gene Expression Assay
GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD35A Gene

mRNA expression in normal human tissues for SNORD35A Gene
mRNA expression by GTEx for SNORD35A GenemRNA expression by BioGPS for SNORD35A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD35A Gene:

SNORD35A
genes like me logo Genes that share expression patterns with SNORD35A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD35A Gene

Orthologs for SNORD35A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD35A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia SNORD35 35
  • 99 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Snord35a 35
  • 80 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia SNORD35 35 35 35
  • 79 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia SNORD35 35
  • 77 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia SNORD35 35 35 35
  • 74 (a)
 OneToMany
dog
(Canis familiaris)
 Mammalia SNORD35 35 35
  • 69 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves SNORD35 35
  • 57 (a)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia SNORD35 35 35
  • 55 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii SNORD35 35
  • 62 (a)
 OneToOne
Species where no ortholog for SNORD35A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD35A Gene

ENSEMBL:
Gene Tree for SNORD35A (if available)
TreeFam:
Gene Tree for SNORD35A (if available)

Paralogs for SNORD35A Gene

No data available for Paralogs for SNORD35A Gene

Variants for SNORD35A Gene

Products:

  1. SNP Genotyping and Copy Number Assay
VarElect - NGS phenotyper. Rapid prioritization of variants from NGS data powered by 100+ GeneCards sources

Sequence variations from dbSNP and Humsavar for SNORD35A Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1001661897 -- 49,489,294(+) AAGA/AAGAAGA upstream_transcript_variant
rs1001944060 -- 49,489,496(+) T/C upstream_transcript_variant
rs1006140111 -- 49,489,791(+) T/C upstream_transcript_variant
rs1007581932 -- 49,491,654(+) G/C downstream_transcript_variant
rs1007633904 -- 49,491,471(+) A/G/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD35A Gene

Variant ID Type Subtype PubMed ID
nsv1160655 CNV deletion 26073780
nsv833862 CNV loss 17160897
nsv833863 CNV loss 17160897
nsv953599 CNV deletion 24416366
nsv960858 CNV duplication 23825009
nsv9739 CNV gain+loss 18304495

Additional Variant Information for SNORD35A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD35A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD35A Gene

Disorders for SNORD35A Gene

Additional Disease Information for SNORD35A

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for SNORD35A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD35A Gene

Publications for SNORD35A Gene

  1. Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs. (PMID: 8764399) Nicoloso M … Bachellerie JP (Journal of molecular biology 1996) 2 3 58
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  3. Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome. (PMID: 10580157) Higa S … Kenmochi N (Gene 1999) 3 58

ExternalLinks

View latest publications for SNORD35A gene in Mastermind

Products for SNORD35A Gene

Sources for SNORD35A Gene

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