Aliases for SNORD22 Gene

Data sources for SNORD22 Gene:

Subcategory (RNA class) for SNORD22 Gene

snoRNA

Aliases for SNORD22 Gene

External Ids for SNORD22 Gene

Previous HGNC Symbols for SNORD22 Gene

  • RNU22

Previous GeneCards Identifiers for SNORD22 Gene

  • GC11M062393
  • GC11M062401
  • GC11M062411
  • GC11M062420
  • GC11M062621
  • GC11M058949
  • GC11M062664
  • GC11M062856
  • GC11M062865
  • GC11M062973
  • GC11M062964
  • GC11M063025
  • GC11M063089
  • GC11M062873
  • GC11M062881
  • GC11M062889
  • GC11M062897
  • GC11M062905
  • GC11M062913
  • GC11M062921
  • GC11M062942
  • GC11M063452

Summaries for SNORD22 Gene

GeneCards Summary for SNORD22 Gene

SNORD22 (Small Nucleolar RNA, C/D Box 22) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD22 include Pontocerebellar Hypoplasia, Type 7 and Hemoglobin C Disease.

Rfam classification for SNORD22 Gene

  • Small nucleolar RNA SNORD22

Additional gene information for SNORD22 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD22 Gene

Genomics for SNORD22 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORD22 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J062878 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 10.9 -28.9 -28909 6.1 CHD2 TBP ZBTB10 SP1 MXD4 CEBPA MNT DEK IKZF1 SMAD5 SLC3A2 HSALNG0084674 lnc-CHRM1-1 SNHG1 CSKMT NXF1 TAF6L GANAB TTC9C MTA2
GH11J062712 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE dbSUPER 10.2 +139.0 138950 3.8 RXRA FOXA2 ZBTB33 RBM22 ZNF316 FOSL1 JUND HNF4A FOXA1 NFE2 HSALNG0084643 piR-45619 HNRNPUL2 TTC9C UBXN1 LBHD1 LRRN4CL POLR2G GANAB UQCC3
GH11J062887 Enhancer 1.1 ENCODE dbSUPER 10.7 -36.7 -36724 4 CEBPA DEK IKZF1 POLR2A NONO NFATC3 NBN SMAD4 SAP130 TRIM25 BSCL2 SNHG1 GANAB TAF6L NXF1 INTS5 CSKMT TUT1 EML3 LOC105369332
GH11J062694 Enhancer 0.8 Ensembl ENCODE 10.5 +158.2 158170 1.1 MNT CTCF BHLHE40 SIN3A REST TRIM22 SMC3 RAD21 MYNN NFE2 BSCL2 TTC9C LBHD1 CSKMT ENSG00000255432 SNORA57 INTS5 GANAB UQCC3 EML3
GH11J062884 Promoter/Enhancer 0.8 Ensembl dbSUPER 10.7 -32.4 -32366 0.4 POLR2A RBM22 SUPT5H SSRP1 SLC3A2 SNHG1 SNORD28 SNORD22 TAF6L GANAB HSALNG0084674 LOC105369333 CHRM1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD22 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD22 gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • SREBP-1b
  • SREBP-1c

Genomic Locations for SNORD22 Gene

Latest Assembly
chr11:62,852,910-62,853,035
(GRCh38/hg38)
Size:
126 bases
Orientation:
Minus strand

Previous Assembly
chr11:62,620,382-62,620,507
(GRCh37/hg19 by Entrez Gene)
Size:
126 bases
Orientation:
Minus strand

Genomic View for SNORD22 Gene

Genes around SNORD22 on UCSC Golden Path with GeneCards custom track
SNORD22 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
SNORD22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD22 Gene

Proteins for SNORD22 Gene

Post-translational modifications for SNORD22 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD22 Gene

Domains & Families for SNORD22 Gene

Gene Families for SNORD22 Gene

genes like me logo Genes that share domains with SNORD22: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD22 Gene

Function for SNORD22 Gene

Phenotypes From GWAS Catalog for SNORD22 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD22 Gene

Localization for SNORD22 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD22 gene
Compartment Confidence
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD22: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD22 Gene

Pathways & Interactions for SNORD22 Gene

PathCards logo

SuperPathways for SNORD22 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD22: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD22 Gene

Drugs & Compounds for SNORD22 Gene

No Compound Related Data Available

Transcripts for SNORD22 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD22 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000066FABB_9606 snoRNA 126 5

RefSeq: NR_000008,

Ensembl: ENST00000384756 (view in UCSC) ,

Rfam: RF00099,

snoDB: SNODB1668,

snOPY: Homo_sapiens300162,

URS000007BC04_9606 snoRNA 125 1

ENA: L36588.1:797..921:misc_RNA, U40580.1:3346..3470:ncRNA,

URS0001BC66E5_9606 snoRNA 125 1

Rfam: RF00099,

SNORD22 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD22 Gene

No ASD Table

Relevant External Links for SNORD22 Gene

GeneLoc Exon Structure for
SNORD22

No data available for mRNA/cDNA for SNORD22 Gene

Expression for SNORD22 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD22 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD22

SOURCE GeneReport for Unigene cluster for SNORD22 Gene:

Hs.744737
genes like me logo Genes that share expression patterns with SNORD22: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD22 Gene

Orthologs for SNORD22 Gene

Evolution for SNORD22 Gene

ENSEMBL:
Gene Tree for SNORD22 (if available)
TreeFam:
Gene Tree for SNORD22 (if available)

No data available for Orthologs for SNORD22 Gene

Paralogs for SNORD22 Gene

No data available for Paralogs for SNORD22 Gene

Variants for SNORD22 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SNORD22 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SNORD22 Gene

Variant ID Type Subtype PubMed ID
nsv1159903 CNV duplication 26073780
nsv508636 CNV deletion 20534489
nsv509416 CNV insertion 20534489

Additional Variant Information for SNORD22 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD22

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD22 Gene

Disorders for SNORD22 Gene

MalaCards: The human disease database

(2) MalaCards diseases for SNORD22 Gene - From: COP

Disorder Aliases PubMed IDs
pontocerebellar hypoplasia, type 7
  • pch7
hemoglobin c disease
  • hb-c disease
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD22

genes like me logo Genes that share disorders with SNORD22: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD22 Gene

Publications for SNORD22 Gene

  1. The U22 host gene (UHG): chromosomal localization of UHG and distribution of U22 small nucleolar RNA. (PMID: 9387929) Frey MR … Matera AG (Histochemistry and cell biology 1997) 2 3 23
  2. A mammalian gene with introns instead of exons generating stable RNA products. (PMID: 8559254) Tycowski KT … Steitz JA (Nature 1996) 2 3 23
  3. Requirement for intron-encoded U22 small nucleolar RNA in 18S ribosomal RNA maturation. (PMID: 7985025) Tycowski KT … Steitz JA (Science (New York, N.Y.) 1994) 3 23
  4. TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions. (PMID: 27609421) Banks CA … Washburn MP (Molecular & cellular proteomics : MCP 2016) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3

Products for SNORD22 Gene

Sources for SNORD22 Gene