SNORD12C Gene (RNA Gene)

Small Nucleolar RNA, C/D Box 12C

GC20P049347
GIFtS:
16
See more...

Aliases for SNORD12C Gene

Subcategory (RNA class) for SNORD12C Gene

snoRNA

Number of RNA Genes sources:

4 / 17

Aliases for SNORD12C Gene

  • Small Nucleolar RNA, C/D Box 12C 2 3 5
  • SNORD12C 2 5 170
  • Small Nucleolar RNA, C/D Box 106 2 3
  • RNA, U106 Small Nucleolar 2 3
  • U106 2 3
  • SNODB1186 177
  • SNORD106 3
  • SNODB136 177
  • RF00581 168
  • RNU106 3
  • E2-1 3
  • E2 3
  • E3 3

External Ids for SNORD12C Gene

Previous HGNC Symbols for SNORD12C Gene

  • RNU106
  • SNORD106

Previous GeneCards Identifiers for SNORD12C Gene

  • GC20U900298
  • GC20P047347
  • GC20P047895
  • GC20P044645
  • GC20P049282
  • GC20P049286
  • GC20P049313
  • GC20P049309
  • GC20P049317
  • GC20P049339
  • GC20P049287
  • GC20P049291
  • GC20P049295
  • GC20P049299
  • GC20P049304

Summaries for SNORD12C Gene

GeneCards Summary for SNORD12C Gene

SNORD12C (Small Nucleolar RNA, C/D Box 12C) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD12C include Human Granulocytic Anaplasmosis.

Rfam classification for SNORD12C Gene

  • Small nucleolar SNORD12/SNORD106

Additional gene information for SNORD12C Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD12C Gene

Genomics for SNORD12C Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for SNORD12C Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH20J049306 Enhancer 0.7 Ensembl 12.2 +28.2 28161 1 SOX13 ZHX2 PKNOX1 SMARCA5 CTBP1 ESRRA ZNF217 TEAD1 HCFC1 MBD2 ZFAS1 SNORD12 SNORD12B ZNFX1 SNORD12C CSE1L lnc-DDX27-4 piR-57133-372 KCNB1
GH20J049236 Enhancer 0.3 ENCODE 12.2 -41.3 -41281 1.4 EZH2 NONHSAG031974.2 CSE1L ZFAS1 SNORD12 SNORD12B SNORD12C ZNFX1 piR-57461-133 STAU1 DDX27
GH20J049275 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 +3.6 3565 14.3 CEBPG SP1 HNRNPL CREB1 GATAD2A ATF7 YBX1 PRDM10 ZNF629 REST ZNFX1 ZFAS1 SNORD12 DDX27 CSE1L SNORD12B B4GALT5 RNF114 ARFGEF2 PTGIS
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD12C on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD12C gene promoter:
  • AML1a
  • Bach1
  • Egr-2
  • HFH-1
  • HOXA3
  • HTF
  • LCR-F1
  • NF-kappaB
  • NF-kappaB1
  • Sp1

Genomic Locations for SNORD12C Gene

Genomic Locations for SNORD12C Gene
chr20:49,278,940-49,279,028
(GRCh38/hg38)
Size:
89 bases
Orientation:
Plus strand
chr20:47,895,477-47,895,565
(GRCh37/hg19)
Size:
89 bases
Orientation:
Plus strand

Genomic View for SNORD12C Gene

Genes around SNORD12C on UCSC Golden Path with GeneCards custom track
SNORD12C in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORD12C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD12C Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORD12C Gene

Proteins for SNORD12C Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORD12C Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD12C Gene

Domains & Families for SNORD12C Gene

Gene Families for SNORD12C Gene

HGNC:
genes like me logo Genes that share domains with SNORD12C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD12C Gene

Function for SNORD12C Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for SNORD12C Gene

Animal Model Products

CRISPR Products

miRNA for SNORD12C Gene

miRTarBase miRNAs that target SNORD12C

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNORD12C Gene

Localization for SNORD12C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD12C gene
Compartment Confidence
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD12C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD12C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD12C Gene

Pathways & Interactions for SNORD12C Gene

PathCards logo

SuperPathways for SNORD12C Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD12C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD12C: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD12C Gene

Drugs & Compounds for SNORD12C Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for SNORD12C Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD12C Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000071403B_9606 snoRNA 89 4

Ensembl: ENST00000386307 (view in UCSC) ,

Rfam: RF00581,

snoDB: SNODB1186,

snOPY: Homo_sapiens300491,

URS0000359B05_9606 snoRNA 79 4

HGNC: 10105,

RefSeq: NR_002433,

snoDB: SNODB136,

ENA: AY349607.1:1..79:ncRNA,

SNORD12C in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD12C Gene

No ASD Table

Relevant External Links for SNORD12C Gene

GeneLoc Exon Structure for
SNORD12C

No data available for mRNA/cDNA for SNORD12C Gene

Expression for SNORD12C Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD12C Gene

mRNA expression in normal human tissues for SNORD12C Gene
mRNA expression by GTEx for SNORD12C Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD12C

genes like me logo Genes that share expression patterns with SNORD12C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD12C Gene

Orthologs for SNORD12C Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD12C Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia SNORD12 31
  • 100 (a)
 OneToOne
Dog
(Canis familiaris)
 Mammalia SNORD12 31
  • 86 (a)
 OneToOne
Cow
(Bos Taurus)
 Mammalia SNORD12 31
  • 83 (a)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Gm25878 31
  • 81 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia SNORD12 31
  • 80 (a)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia SNORD12 31
  • 76 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves SNORD12 31
  • 66 (a)
 OneToMany
Lizard
(Anolis carolinensis)
 Reptilia SNORD12 31
  • 77 (a)
 ManyToMany
Zebrafish
(Danio rerio)
 Actinopterygii SNORD12 31
  • 65 (a)
 ManyToMany
Species where no ortholog for SNORD12C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SNORD12C Gene

ENSEMBL:
Gene Tree for SNORD12C (if available)
TreeFam:
Gene Tree for SNORD12C (if available)

Paralogs for SNORD12C Gene

No data available for Paralogs for SNORD12C Gene

Variants for SNORD12C Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for SNORD12C Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORD12C Gene

Variant ID Type Subtype PubMed ID
dgv1248e212 CNV loss 25503493
nsv1064443 CNV gain 25217958
nsv1067146 CNV loss 25217958
nsv437839 CNV loss 16327808

Additional Variant Information for SNORD12C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD12C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD12C Gene

Disorders for SNORD12C Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORD12C Gene - From: DISEASES

Disorder Aliases PubMed IDs
human granulocytic anaplasmosis
  • hge
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD12C

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SNORD12C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD12C Gene

Publications for SNORD12C Gene

  1. Identification of 13 novel human modification guide RNAs. (PMID: 14602913) Vitali P … Cavaillé J (Nucleic acids research 2003) 2 3
  2. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. (PMID: 26867678) Chen S … Voit R (Nature communications 2016) 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3
  4. Genes for E1, E2, and E3 small nucleolar RNAs. (PMID: 8415643) Nag MK … Eliceiri GL (Proceedings of the National Academy of Sciences of the United States of America 1993) 3

ExternalLinks

View latest publications for SNORD12C gene in Mastermind

Products for SNORD12C Gene

Sources for SNORD12C Gene