SNORD12B Gene (RNA Gene)

Small Nucleolar RNA, C/D Box 12B

GC20P049345
GIFtS:
15
See more...

Aliases for SNORD12B Gene

Data sources for SNORD12B Gene:

Subcategory (RNA class) for SNORD12B Gene

snoRNA

Aliases for SNORD12B Gene

External Ids for SNORD12B Gene

Previous GeneCards Identifiers for SNORD12B Gene

  • GC19U900762
  • GC20P047898
  • GC20P047904
  • GC20P047909
  • GC20P047916
  • GC20P049283
  • GC20P049289
  • GC20P049326
  • GC20P049327
  • GC20P049337
  • GC20P049340
  • GC20P049293
  • GC20P049297
  • GC20P049301
  • GC20P049307
  • GC20P049311
  • GC20P049315
  • GC20P049319
  • GC20P049322

Summaries for SNORD12B Gene

GeneCards Summary for SNORD12B Gene

SNORD12B (Small Nucleolar RNA, C/D Box 12B) is an RNA Gene, and is affiliated with the snoRNA class.

Rfam classification for SNORD12B Gene

  • Small nucleolar SNORD12/SNORD106

Additional gene information for SNORD12B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD12B Gene

Genomics for SNORD12B Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for SNORD12B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD12B on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD12B gene promoter:
  • AML1a
  • Bach1
  • Egr-2
  • HFH-1
  • HOXA3
  • HTF
  • LCR-F1
  • NF-kappaB
  • NF-kappaB1
  • Sp1

Genomic Locations for SNORD12B Gene

Latest Assembly
chr20:49,280,313-49,280,415
(GRCh38/hg38)
Size:
103 bases
Orientation:
Plus strand

Previous Assembly
chr20:47,896,850-47,896,952
(GRCh37/hg19 by Entrez Gene)
Size:
103 bases
Orientation:
Plus strand

chr20:47,896,856-47,896,946
(GRCh37/hg19 by Ensembl)
Size:
91 bases
Orientation:
Plus strand

Genomic View for SNORD12B Gene

Genes around SNORD12B on UCSC Golden Path with GeneCards custom track
SNORD12B in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
SNORD12B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD12B Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORD12B Gene

Proteins for SNORD12B Gene

Products:

  1. Antibodies for research
  2. Protein products for research
  3. Assay products for research

Post-translational modifications for SNORD12B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD12B Gene

Domains & Families for SNORD12B Gene

Gene Families for SNORD12B Gene

HGNC:
genes like me logo Genes that share domains with SNORD12B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD12B Gene

Function for SNORD12B Gene

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  1. Animal Models for research
  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes From GWAS Catalog for SNORD12B Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD12B Gene

Localization for SNORD12B Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD12B gene
Compartment Confidence
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD12B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD12B Gene

Pathways & Interactions for SNORD12B Gene

PathCards logo

SuperPathways for SNORD12B Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD12B: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD12B Gene

Drugs & Compounds for SNORD12B Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for SNORD12B Gene

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  2. miRNA products for research
  3. Inhibitory RNAs for research
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Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD12B Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000643FAE_9606 snoRNA 91 4

Ensembl: ENST00000410433 (view in UCSC) ,

Rfam: RF00581,

snoDB: SNODB394,

snOPY: Homo_sapiens300763,

URS000075BC17_9606 snoRNA 103 2

RefSeq: NR_003695,

snoDB: SNODB1319,

URS0001BC2E6D_9606 snoRNA 91 1

Rfam: RF00581,

SNORD12B in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

CRISPR products for research

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD12B Gene

No ASD Table

Relevant External Links for SNORD12B Gene

GeneLoc Exon Structure for
SNORD12B

No data available for mRNA/cDNA for SNORD12B Gene

Expression for SNORD12B Gene

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mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD12B Gene

mRNA expression in normal human tissues for SNORD12B Gene
mRNA expression by GTEx for SNORD12B Gene

mRNA differential expression in normal tissues according to GTEx for SNORD12B Gene

This gene is overexpressed in Whole Blood (x8.4).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD12B

SOURCE GeneReport for Unigene cluster for SNORD12B Gene:

Hs.711216
genes like me logo Genes that share expression patterns with SNORD12B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD12B Gene

Orthologs for SNORD12B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD12B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia SNORD12 31
  • 100 (a)
 OneToOne
Dog
(Canis familiaris)
 Mammalia SNORD12 31
  • 95 (a)
 OneToOne
Cow
(Bos Taurus)
 Mammalia SNORD12 31
  • 92 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia SNORD12 31 31
  • 82 (a)
 ManyToMany
Mouse
(Mus musculus)
 Mammalia Gm23201 31
  • 80 (a)
 ManyToMany
Gm24123 31
  • 69 (a)
 ManyToMany
Platypus
(Ornithorhynchus anatinus)
 Mammalia SNORD12 31 31 31 31 31
  • 63 (a)
 ManyToMany
Chicken
(Gallus gallus)
 Aves SNORD12 31
  • 71 (a)
 OneToMany
Lizard
(Anolis carolinensis)
 Reptilia SNORD12 31
  • 63 (a)
 ManyToMany
Zebrafish
(Danio rerio)
 Actinopterygii SNORD12 31 31 31
  • 66 (a)
 ManyToMany
Species where no ortholog for SNORD12B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SNORD12B Gene

ENSEMBL:
Gene Tree for SNORD12B (if available)
TreeFam:
Gene Tree for SNORD12B (if available)

Paralogs for SNORD12B Gene

No data available for Paralogs for SNORD12B Gene

Variants for SNORD12B Gene

Products:

  1. SNP Genotyping and Copy Number Assays for research

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SNORD12B Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SNORD12B Gene

Variant ID Type Subtype PubMed ID
dgv1248e212 CNV loss 25503493
nsv1064443 CNV gain 25217958
nsv1067146 CNV loss 25217958
nsv437839 CNV loss 16327808

Additional Variant Information for SNORD12B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD12B

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD12B Gene

Disorders for SNORD12B Gene

Additional Disease Information for SNORD12B

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for SNORD12B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD12B Gene

Publications for SNORD12B Gene

  1. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3
  3. snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang JH … Qu LH (Nucleic acids research 2006) 3

ExternalLinks

View latest publications for SNORD12B gene in Mastermind

Products for SNORD12B Gene

Sources for SNORD12B Gene