Small nucleolar RNAs (snoRNAs), like SNORD112, guide the formation of 2-prime O-methylation of ribosomal RNA (rRNA) and U small nuclear RNAs (snRNAs) through a specific RNA duplex at each modification site (Cavaille et al., 2002 [PubMed 12045206]).[supplied by OMIM, Nov 2010] See more...

Aliases for SNORD112 Gene

Subcategory (RNA class) for SNORD112 Gene

snoRNA

Number of RNA Genes sources:

3 / 17

Aliases for SNORD112 Gene

  • Small Nucleolar RNA, C/D Box 112 2 3 5
  • SNORD112 2 5 170
  • 14q(0) 2 3
  • SNODB1117 177
  • RF01169 168

External Ids for SNORD112 Gene

Previous GeneCards Identifiers for SNORD112 Gene

  • GC14U900587
  • GC14P100445
  • GC14P100461
  • GC14P100845
  • GC14P100941
  • GC14P101364
  • GC14P081545
  • GC14P101400
  • GC14P102117
  • GC14P101088
  • GC14P101290
  • GC14P103475
  • GC14P103673
  • GC14P103878
  • GC14P104260
  • GC14P101919
  • GC14P102227
  • GC14P102394
  • GC14P102574
  • GC14P102746
  • GC14P102920
  • GC14P103097
  • GC14P103293

Summaries for SNORD112 Gene

Entrez Gene Summary for SNORD112 Gene

  • Small nucleolar RNAs (snoRNAs), like SNORD112, guide the formation of 2-prime O-methylation of ribosomal RNA (rRNA) and U small nuclear RNAs (snRNAs) through a specific RNA duplex at each modification site (Cavaille et al., 2002 [PubMed 12045206]).[supplied by OMIM, Nov 2010]

GeneCards Summary for SNORD112 Gene

SNORD112 (Small Nucleolar RNA, C/D Box 112) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD112 include Angelman Syndrome.

Rfam classification for SNORD112 Gene

  • Small nucleolar RNA SNORD112

Additional gene information for SNORD112 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD112 Gene

Genomics for SNORD112 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORD112 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORD112 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORD112 gene promoter:
  • aMEF-2
  • AML1a
  • C/EBPalpha
  • E4BP4
  • FOXJ2
  • FOXJ2 (long isoform)
  • MyoD
  • Olf-1
  • Pax-5

Genomic Locations for SNORD112 Gene

Genomic Locations for SNORD112 Gene
chr14:100,897,920-100,897,996
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand
chr14:101,361,107-101,402,336
(GRCh37/hg19)
Size:
41,230 bases
Orientation:
Plus strand

Genomic View for SNORD112 Gene

Genes around SNORD112 on UCSC Golden Path with GeneCards custom track
SNORD112 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORD112 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD112 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD112 Gene

Proteins for SNORD112 Gene

Post-translational modifications for SNORD112 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD112 Gene

Domains & Families for SNORD112 Gene

Gene Families for SNORD112 Gene

genes like me logo Genes that share domains with SNORD112: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORD112 Gene

Function for SNORD112 Gene

Phenotypes From GWAS Catalog for SNORD112 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD112 Gene

Localization for SNORD112 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORD112 gene
Compartment Confidence
nucleus 1

Gene Ontology (GO) - Cellular Components for SNORD112 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORD112: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORD112 Gene

Pathways & Interactions for SNORD112 Gene

PathCards logo

SuperPathways for SNORD112 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORD112 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORD112: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORD112 Gene

Drugs & Compounds for SNORD112 Gene

No Compound Related Data Available

Transcripts for SNORD112 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORD112 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00007014CB_9606 snoRNA 77 6

HGNC: 32777,

RefSeq: NR_003080,

Ensembl: ENST00000458974 (view in UCSC) ,

Rfam: RF01169,

snoDB: SNODB1117,

snOPY: Homo_sapiens300354,

SNORD112 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD112 Gene

No ASD Table

Relevant External Links for SNORD112 Gene

GeneLoc Exon Structure for
SNORD112

No data available for mRNA/cDNA for SNORD112 Gene

Expression for SNORD112 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORD112

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD112 Gene

Orthologs for SNORD112 Gene

Evolution for SNORD112 Gene

ENSEMBL:
Gene Tree for SNORD112 (if available)
TreeFam:
Gene Tree for SNORD112 (if available)

No data available for Orthologs for SNORD112 Gene

Paralogs for SNORD112 Gene

No data available for Paralogs for SNORD112 Gene

Variants for SNORD112 Gene

Additional dbSNP identifiers (rs#s) for SNORD112 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORD112 Gene

Variant ID Type Subtype PubMed ID
esv3635518 CNV gain 21293372
nsv1052082 CNV loss 25217958

Additional Variant Information for SNORD112 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD112

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORD112 Gene

Disorders for SNORD112 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORD112 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
angelman syndrome
  • as
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD112

genes like me logo Genes that share disorders with SNORD112: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD112 Gene

Publications for SNORD112 Gene

  1. Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. (PMID: 12045206) Cavaillé J … Bachellerie JP (Human molecular genetics 2002) 2 3
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3

Products for SNORD112 Gene

Sources for SNORD112 Gene