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Aliases for SNORC Gene

Aliases for SNORC Gene

  • Secondary Ossification Center Associated Regulator Of Chondrocyte Maturation 2 3
  • C2orf82 3 4 5
  • Chromosome 2 Open Reading Frame 82 2 5
  • Small Novel Rich In Cartilage 2 3
  • Uncharacterized Protein C2orf82 3
  • ASCL830 3
  • UNQ830 3

External Ids for SNORC Gene

Previous HGNC Symbols for SNORC Gene

  • C2orf82

Summaries for SNORC Gene

GeneCards Summary for SNORC Gene

SNORC (Secondary Ossification Center Associated Regulator Of Chondrocyte Maturation) is a Protein Coding gene.

Additional gene information for SNORC Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORC Gene

Genomics for SNORC Gene

GeneHancer (GH) Regulatory Elements for SNORC Gene

Promoters and enhancers for SNORC Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I232855 Enhancer 1.2 ENCODE dbSUPER 564.5 +1.3 1335 6.8 FOXA2 MLX ARID4B SIN3A DMAP1 ETS1 YY1 SLC30A9 ATF7 RXRA SNORC NGEF ATG16L1 SCARNA5 PIR45244 GIGYF2
GH02I232870 Promoter/Enhancer 0.9 EPDnew dbSUPER 550.4 +13.0 13040 0.1 ZGPAT POLR2A ZHX2 SNORC PIR45244
GH02I232872 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 20.4 +18.1 18091 4.9 DRAP1 ELF3 CTCF MXI1 SAP130 SUZ12 ARID4B SIN3A BACH1 DMAP1 SNORC NGEF GIGYF2 LOC101928881 KCNJ13 ATG16L1 SCARNA5 PIR45244
GH02I232900 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 21.4 +44.5 44528 1.8 JUN MAX SIN3A ZIC2 RAD21 FOSL1 POLR2A SMC3 FOSL2 FOS NGEF SNORC LOC101928881 INPP5D PIR45244
GH02I232873 Enhancer 1 ENCODE dbSUPER 22.1 +15.1 15096 0.2 ELF3 FOXA2 DNMT3B THRB ZNF48 ZSCAN9 RARA CREM THAP11 MIXL1 PIR45244 SNORC LOC101928881 NGEF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORC on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORC Gene

Genomic Locations for SNORC Gene
chr2:232,857,270-232,878,708
(GRCh38/hg38)
Size:
21,439 bases
Orientation:
Plus strand
chr2:233,721,980-233,743,418
(GRCh37/hg19)

Genomic View for SNORC Gene

Genes around SNORC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORC Gene

Proteins for SNORC Gene

  • Protein details for SNORC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX34-CB082_HUMAN
    Recommended name:
    Uncharacterized protein C2orf82
    Protein Accession:
    Q6UX34

    Protein attributes for SNORC Gene

    Size:
    121 amino acids
    Molecular mass:
    12073 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SNORC Gene

Post-translational modifications for SNORC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SNORC Gene

Domains & Families for SNORC Gene

Gene Families for SNORC Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for SNORC Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORC: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORC Gene

Function for SNORC Gene

Phenotypes From GWAS Catalog for SNORC Gene

genes like me logo Genes that share phenotypes with SNORC: view

Animal Models for SNORC Gene

MGI Knock Outs for SNORC:

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SNORC Gene

Localization for SNORC Gene

Subcellular locations from UniProtKB/Swiss-Prot for SNORC Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORC gene
Compartment Confidence
extracellular 3
plasma membrane 2
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SNORC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0031012 extracellular matrix IEA --
GO:0071944 cell periphery ISS --
genes like me logo Genes that share ontologies with SNORC: view

Pathways & Interactions for SNORC Gene

SuperPathways for SNORC Gene

No Data Available

Interacting Proteins for SNORC Gene

Gene Ontology (GO) - Biological Process for SNORC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051216 cartilage development ISS --
genes like me logo Genes that share ontologies with SNORC: view

No data available for Pathways by source and SIGNOR curated interactions for SNORC Gene

Drugs & Compounds for SNORC Gene

No Compound Related Data Available

Transcripts for SNORC Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORC Gene

No ASD Table

Relevant External Links for SNORC Gene

GeneLoc Exon Structure for
SNORC
ECgene alternative splicing isoforms for
SNORC

Expression for SNORC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of SNORC Gene:

SNORC
genes like me logo Genes that share expression patterns with SNORC: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORC Gene

Orthologs for SNORC Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2orf82 34
  • 100 (a)
OneToOne
C2BH2orf82 33
  • 99.72 (n)
cow
(Bos Taurus)
Mammalia C3H2orf82 33
  • 88.43 (n)
C2orf82 34
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C25H2orf82 33
  • 86.14 (n)
C2orf82 34
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 3110079O15Rik 34 16 33
  • 79.06 (n)
OneToOne
chicken
(Gallus gallus)
Aves C9H2ORF82 34 33
  • 66.07 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C2orf82 34
  • 54 (a)
OneToOne
Species where no ortholog for SNORC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORC Gene

ENSEMBL:
Gene Tree for SNORC (if available)
TreeFam:
Gene Tree for SNORC (if available)

Paralogs for SNORC Gene

No data available for Paralogs for SNORC Gene

Variants for SNORC Gene

Sequence variations from dbSNP and Humsavar for SNORC Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000254568 -- 232,875,748(+) C/T intron_variant
rs1000304389 -- 232,875,538(+) A/G/T intron_variant
rs1000779742 -- 232,866,040(+) A/T 5_prime_UTR_variant, genic_upstream_transcript_variant
rs1000984549 -- 232,871,395(+) C/T intron_variant
rs1001091032 -- 232,866,078(+) G/T 5_prime_UTR_variant, genic_upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORC Gene

Variant ID Type Subtype PubMed ID
dgv4188n100 CNV gain 25217958
nsv1009825 CNV gain 25217958
nsv834570 CNV gain 17160897
nsv953203 CNV deletion 24416366

Additional Variant Information for SNORC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORC Gene

Disorders for SNORC Gene

Additional Disease Information for SNORC

No disorders were found for SNORC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORC Gene

Publications for SNORC Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 2 3 4 58
  2. Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency. (PMID: 28323137) Heinonen J … Säämänen AM (Osteoarthritis and cartilage 2017) 2 3 58
  3. Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. (PMID: 21624478) Heinonen J … Säämänen AM (Osteoarthritis and cartilage 2011) 2 3 58
  4. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 58
  5. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 58

Products for SNORC Gene

Sources for SNORC Gene

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