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Aliases for SNORA8 Gene

Subcategory (RNA class) for SNORA8 Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORA8 Gene

  • Small Nucleolar RNA, H/ACA Box 8 2 3 5
  • ACA8 Small Nucleolar RNA 3
  • ACA8 SnoRNA 3
  • ACA8 3

External Ids for SNORA8 Gene

Previous GeneCards Identifiers for SNORA8 Gene

  • GC11M093144
  • GC11M093148
  • GC11M093155
  • GC11M093161
  • GC11M093167
  • GC11M093177
  • GC11M093186
  • GC11M093197
  • GC11M093468
  • GC11M093474
  • GC11M089543
  • GC11M093482
  • GC11M093498
  • GC11M093506
  • GC11M093514
  • GC11M093524
  • GC11M093540
  • GC11M093564
  • GC11M093735
  • GC11M093746
  • GC11M093943
  • GC11M093758
  • GC11M093768
  • GC11M093777
  • GC11M093786
  • GC11M093797
  • GC11M093808
  • GC11M093938
  • GC11M093924

Summaries for SNORA8 Gene

GeneCards Summary for SNORA8 Gene

SNORA8 (Small Nucleolar RNA, H/ACA Box 8) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORA8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA8 Gene

Genomics for SNORA8 Gene

GeneHancer (GH) Regulatory Elements for SNORA8 Gene

Promoters and enhancers for SNORA8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J093731 Enhancer 0.4 ENCODE 600.7 +0.1 87 1.1 ZBED1 POLR2A SUPT5H GC11M094040 GC11M094041 GC11M094042 GC11M094043 GC11M094045 GC11M094046 GC11M094047 GC11M094048 GC11M094049 GC11M094051
GH11J093783 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.3 -52.7 -52702 4 ZFX ELF3 MNT NKRF POLR2A ZNF121 ZSCAN21 CDC5L ZBTB7A ELF1 MED17 TAF1D C11orf54 SNORA1 MRE11 ANKRD49 SNORA40 SNORA18 SNORA25 SNORA32
GH11J093654 Enhancer 0.9 Ensembl ENCODE 9.9 +78.0 77998 5 CTCF EGR1 RAD21 IKZF2 TRIM22 SCRT2 RUNX3 RFX5 SMC3 JUNB GC11P093655 C11orf54 CEP295 TAF1D SNORA1 SNORA25 SNORA32 SNORD6 MED17 SNORA18
GH11J093796 Promoter 0.7 EPDnew 10.6 -64.0 -64024 0.1 RFX1 NCOR1 EMSY MED17 C11orf54 SNORA1 SNORA18 SNORA40 SNORA8 SNORD5 SNORD6 SNORA25 SNORA32
GH11J093768 Enhancer 0.6 Ensembl 11.9 -36.9 -36902 2 CBFA2T2 SOX13 SOX6 NFE2 ZNF530 KDM1A ZEB2 SOX5 CBFA2T3 CEP295 SNORA40 SNORA1 SNORA18 SNORA25 SNORA32 SNORA8 SNORD5 SNORD6 MED17
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA8 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA8 gene promoter:
  • aMEF-2
  • GATA-1
  • GR
  • MEF-2
  • MEF-2A
  • POU2F1
  • POU2F1a
  • RORalpha1

Genomic Locations for SNORA8 Gene

Genomic Locations for SNORA8 Gene
chr11:93,732,361-93,732,499
(GRCh38/hg38)
Size:
139 bases
Orientation:
Minus strand
chr11:93,465,527-93,465,665
(GRCh37/hg19)
Size:
139 bases
Orientation:
Minus strand

Genomic View for SNORA8 Gene

Genes around SNORA8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA8 Gene

Proteins for SNORA8 Gene

Post-translational modifications for SNORA8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA8 Gene

Domains & Families for SNORA8 Gene

Gene Families for SNORA8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA8 Gene

Function for SNORA8 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA8 Gene

Localization for SNORA8 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORA8 gene
Compartment Confidence
plasma membrane 1

Gene Ontology (GO) - Cellular Components for SNORA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA8: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORA8 Gene

Pathways & Interactions for SNORA8 Gene

PathCards logo

SuperPathways for SNORA8 Gene

No Data Available

Interacting Proteins for SNORA8 Gene

Gene Ontology (GO) - Biological Process for SNORA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA8: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA8 Gene

Drugs & Compounds for SNORA8 Gene

No Compound Related Data Available

Transcripts for SNORA8 Gene

mRNA/cDNA for SNORA8 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

Unigene Clusters for SNORA8 Gene

Small nucleolar RNA, H/ACA box 8:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA8 Gene

No ASD Table

Relevant External Links for SNORA8 Gene

GeneLoc Exon Structure for
SNORA8
ECgene alternative splicing isoforms for
SNORA8

Expression for SNORA8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA8 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA8 Gene:

SNORA8

SOURCE GeneReport for Unigene cluster for SNORA8 Gene:

Hs.741060
genes like me logo Genes that share expression patterns with SNORA8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA8 Gene

Orthologs for SNORA8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA8 35
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25791 35
  • 91 (a)
ManyToMany
Gm26236 35
  • 90 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA8 35
  • 83 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA8 35
  • 80 (a)
OneToMany
cow
(Bos Taurus)
Mammalia SNORA8 35
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA8 35
  • 78 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA8 35
  • 75 (a)
OneToMany
Species where no ortholog for SNORA8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA8 Gene

ENSEMBL:
Gene Tree for SNORA8 (if available)
TreeFam:
Gene Tree for SNORA8 (if available)

Paralogs for SNORA8 Gene

No data available for Paralogs for SNORA8 Gene

Variants for SNORA8 Gene

Sequence variations from dbSNP and Humsavar for SNORA8 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1002861927 -- 93,732,336(-) G/A/C downstream_transcript_variant
rs1003060913 -- 93,731,891(-) T/C downstream_transcript_variant
rs1004421250 -- 93,732,729(-) T/C/G upstream_transcript_variant
rs1006611468 -- 93,732,066(-) C/G downstream_transcript_variant
rs1007052149 -- 93,732,274(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA8 Gene

Variant ID Type Subtype PubMed ID
esv3627294 CNV gain 21293372
nsv832232 CNV gain 17160897

Additional Variant Information for SNORA8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA8 Gene

Disorders for SNORA8 Gene

Additional Disease Information for SNORA8

No disorders were found for SNORA8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA8 Gene

Publications for SNORA8 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  5. Pseudouridine distribution in mammalian 18 S ribosomal RNA. A major cluster in the central region of the molecule. (PMID: 3342024) Maden EH … Wakeman JA (The Biochemical journal 1988) 3 58

Products for SNORA8 Gene

Sources for SNORA8 Gene

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