Aliases for SNORA8 Gene

Subcategory (RNA class) for SNORA8 Gene

snoRNA

Number of RNA Genes sources:

4 / 17

Aliases for SNORA8 Gene

  • Small Nucleolar RNA, H/ACA Box 8 2 3 5
  • SNORA8 2 5 170
  • ACA8 2 3
  • ACA8 Small Nucleolar RNA 3
  • ACA8 SnoRNA 3
  • SNODB146 177
  • RF00393 168

External Ids for SNORA8 Gene

Previous GeneCards Identifiers for SNORA8 Gene

  • GC11M093144
  • GC11M093148
  • GC11M093155
  • GC11M093161
  • GC11M093167
  • GC11M093177
  • GC11M093186
  • GC11M093197
  • GC11M093468
  • GC11M093474
  • GC11M089543
  • GC11M093482
  • GC11M093498
  • GC11M093506
  • GC11M093514
  • GC11M093524
  • GC11M093540
  • GC11M093564
  • GC11M093735
  • GC11M093746
  • GC11M093943
  • GC11M094032
  • GC11M094045
  • GC11M094223
  • GC11M093758
  • GC11M093768
  • GC11M093777
  • GC11M093786
  • GC11M093797
  • GC11M093808
  • GC11M093938
  • GC11M093924

Summaries for SNORA8 Gene

GeneCards Summary for SNORA8 Gene

SNORA8 (Small Nucleolar RNA, H/ACA Box 8) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORA8 include Cone-Rod Dystrophy 19.

Rfam classification for SNORA8 Gene

  • Small nucleolar RNA SNORA8

Additional gene information for SNORA8 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA8 Gene

Genomics for SNORA8 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNORA8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J093731 Enhancer 0.6 Ensembl ENCODE 600.7 +0.1 106 1.2 POLR2A RBFOX2 RBM22 SUPT5H POLR2B ZBED1 MIR1304 NONHSAG009375.2 SNORA1 SNORA18 SNORA25 SNORA32 SNORA8 SNORD5 SNORD6 piR-31447
GH11J093783 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 11.3 -53.0 -53002 4.2 HNRNPL CREB1 GATAD2A ZNF629 ZNF512 LEF1 ZNF692 POLR2A BACH1 JUND MED17 TAF1D C11orf54 SNORA1 MRE11 ANKRD49 SNORA18 SNORA25 SNORA32 SNORA40
GH11J093654 Enhancer 0.8 Ensembl ENCODE 9.9 +78.1 78147 4.9 CTCF FOXA1 RAD21 TRIM22 SCRT2 EGR1 RUNX3 SMC3 RFX5 GATA3 C11orf54 CEP295 TAF1D SNORA1 SNORA25 SNORA32 SNORD6 MED17 SNORA18 SNORA8
GH11J093768 Enhancer 0.6 Ensembl 11.9 -37.0 -37002 1.8 SOX6 SOX13 NFE2 ZNF530 HDAC2 KDM1A ZEB2 SOX5 CBFA2T2 CBFA2T3 CEP295 SNORA40 SNORA1 SNORA18 SNORA25 SNORA32 SNORA8 SNORD5 SNORD6 MED17
GH11J093796 Promoter 0.6 EPDnew 10.6 -64.0 -64024 0.1 RFX1 NCOR1 ARID1B EMSY RF00015-012 SNODB1210 MED17 C11orf54 SNORA1 SNORA18 SNORA40 SNORA8 SNORD5 SNORD6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA8 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNORA8 gene promoter:
  • aMEF-2
  • GATA-1
  • GR
  • MEF-2
  • MEF-2A
  • POU2F1
  • POU2F1a
  • RORalpha1

Genomic Locations for SNORA8 Gene

Genomic Locations for SNORA8 Gene
chr11:93,732,361-93,732,499
(GRCh38/hg38)
Size:
139 bases
Orientation:
Minus strand
chr11:93,465,527-93,465,665
(GRCh37/hg19)
Size:
139 bases
Orientation:
Minus strand

Genomic View for SNORA8 Gene

Genes around SNORA8 on UCSC Golden Path with GeneCards custom track
SNORA8 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNORA8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA8 Gene

Proteins for SNORA8 Gene

Post-translational modifications for SNORA8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA8 Gene

Domains & Families for SNORA8 Gene

Gene Families for SNORA8 Gene

genes like me logo Genes that share domains with SNORA8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORA8 Gene

Function for SNORA8 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA8 Gene

Localization for SNORA8 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORA8 gene
Compartment Confidence
plasma membrane 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Gene Ontology (GO) - Cellular Components for SNORA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA8: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORA8 Gene

Pathways & Interactions for SNORA8 Gene

PathCards logo

SuperPathways for SNORA8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA8: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNORA8 Gene

Drugs & Compounds for SNORA8 Gene

No Compound Related Data Available

Transcripts for SNORA8 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNORA8 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00003A960A_9606 snoRNA 139 7

HGNC: 32596,

RefSeq: NR_002920,

Ensembl: ENST00000384574 (view in UCSC) ,

Rfam: RF00393,

snoDB: SNODB146,

snOPY: Homo_sapiens300750,

ENA: AJ609454.1:1..139:ncRNA,

SNORA8 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for SNORA8 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA8 Gene

No ASD Table

Relevant External Links for SNORA8 Gene

GeneLoc Exon Structure for
SNORA8

Expression for SNORA8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORA8 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNORA8

SOURCE GeneReport for Unigene cluster for SNORA8 Gene:

Hs.741060
genes like me logo Genes that share expression patterns with SNORA8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA8 Gene

Orthologs for SNORA8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA8 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SNORA8 31
  • 100 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Gm25791 31
  • 91 (a)
ManyToMany
Gm26236 31
  • 90 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia SNORA8 31
  • 83 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia SNORA8 31
  • 80 (a)
OneToMany
Cow
(Bos Taurus)
Mammalia SNORA8 31
  • 70 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SNORA8 31
  • 78 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia SNORA8 31
  • 75 (a)
OneToMany
Species where no ortholog for SNORA8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for SNORA8 Gene

ENSEMBL:
Gene Tree for SNORA8 (if available)
TreeFam:
Gene Tree for SNORA8 (if available)

Paralogs for SNORA8 Gene

No data available for Paralogs for SNORA8 Gene

Variants for SNORA8 Gene

Additional dbSNP identifiers (rs#s) for SNORA8 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA8 Gene

Variant ID Type Subtype PubMed ID
esv3627294 CNV gain 21293372
nsv832232 CNV gain 17160897

Additional Variant Information for SNORA8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNORA8 Gene

Disorders for SNORA8 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORA8 Gene - From: DISEASES

Disorder Aliases PubMed IDs
cone-rod dystrophy 19
  • cord19
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORA8

genes like me logo Genes that share disorders with SNORA8: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORA8 Gene

Publications for SNORA8 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3
  3. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3

Products for SNORA8 Gene

Sources for SNORA8 Gene