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Aliases for SNORA74C-1 Gene

Subcategory (RNA class) for SNORA74C-1 Gene

snoRNA

Quality Score for this RNA gene is

13.2

Aliases for SNORA74C-1 Gene

  • Small Nucleolar RNA, H/ACA Box 74C-1 2 3 5

External Ids for SNORA74C-1 Gene

ORGUL Members for SNORA74C-1 Gene

Previous GeneCards Identifiers for SNORA74C-1 Gene

  • GC00U936775

Summaries for SNORA74C-1 Gene

GeneCards Summary for SNORA74C-1 Gene

SNORA74C-1 (Small Nucleolar RNA, H/ACA Box 74C-1) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA74C-1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA74: U19 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs [1]. Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing [2].

Additional gene information for SNORA74C-1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA74C-1 Gene

Genomics for SNORA74C-1 Gene

GeneHancer (GH) Regulatory Elements for SNORA74C-1 Gene

Promoters and enhancers for SNORA74C-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J045983 Enhancer 0.4 Ensembl dbSUPER 600.7 +0.3 291 0.2 SNORA74C-1 TIMM23 PIR61931 GC10P046001
GH10J045982 Enhancer 0.2 dbSUPER 600.7 -1.4 -1410 1.1 SNORA74C-1 TIMM23
GH10J045971 Promoter/Enhancer 1.2 EPDnew Ensembl dbSUPER 0.4 -12.0 -12009 4 PARGP1 TIMM23 AGAP4 AGAP7P SNORA74C-1
GH10J045981 Enhancer 0.2 Ensembl 0.7 -2.9 -2910 0.2 SNORA74C-1 TIMM23
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA74C-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA74C-1 Gene

Genomic Locations for SNORA74C-1 Gene
chr10:45,984,610-45,984,810
(GRCh38/hg38)
Size:
201 bases
Orientation:
Plus strand

Genomic View for SNORA74C-1 Gene

Genes around SNORA74C-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA74C-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA74C-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA74C-1 Gene

ORGUL Member Location for SNORA74C-1 Gene

ORGUL Member Location for SNORA74C-1 gene

Proteins for SNORA74C-1 Gene

Post-translational modifications for SNORA74C-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA74C-1 Gene

Domains & Families for SNORA74C-1 Gene

Gene Families for SNORA74C-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA74C-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA74C-1 Gene

Function for SNORA74C-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA74C-1 Gene

Localization for SNORA74C-1 Gene

Gene Ontology (GO) - Cellular Components for SNORA74C-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA74C-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORA74C-1 Gene

Pathways & Interactions for SNORA74C-1 Gene

PathCards logo

SuperPathways for SNORA74C-1 Gene

No Data Available

Interacting Proteins for SNORA74C-1 Gene

Gene Ontology (GO) - Biological Process for SNORA74C-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA74C-1: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA74C-1 Gene

Drugs & Compounds for SNORA74C-1 Gene

No Compound Related Data Available

Transcripts for SNORA74C-1 Gene

mRNA/cDNA for SNORA74C-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA74C-1 Gene

No ASD Table

Relevant External Links for SNORA74C-1 Gene

GeneLoc Exon Structure for
SNORA74C-1
ECgene alternative splicing isoforms for
SNORA74C-1

Expression for SNORA74C-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA74C-1 Gene

Orthologs for SNORA74C-1 Gene

Evolution for SNORA74C-1 Gene

ENSEMBL:
Gene Tree for SNORA74C-1 (if available)
TreeFam:
Gene Tree for SNORA74C-1 (if available)

No data available for Orthologs for SNORA74C-1 Gene

Paralogs for SNORA74C-1 Gene

No data available for Paralogs for SNORA74C-1 Gene

Variants for SNORA74C-1 Gene

Sequence variations from dbSNP and Humsavar for SNORA74C-1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs10551459 -- 45,983,366(+) ATGTTTCCGAAA/GTTTCCGAAG upstream_transcript_variant
rs1157803249 -- 45,985,147(+) G/C downstream_transcript_variant
rs1158359173 -- 45,983,133(+) A/C upstream_transcript_variant
rs1159181430 -- 45,984,587(+) T/G upstream_transcript_variant
rs1160572312 -- 45,983,626(+) C/T upstream_transcript_variant

Additional Variant Information for SNORA74C-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA74C-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA74C-1 Gene

Disorders for SNORA74C-1 Gene

Additional Disease Information for SNORA74C-1

No disorders were found for SNORA74C-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA74C-1 Gene

Publications for SNORA74C-1 Gene

  1. An updated human snoRNAome. (PMID: 27174936) Jorjani H … Gruber AR (Nucleic acids research 2016) 2 3 58
  2. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang KC … Mattick JS (Nucleic acids research 2005) 1
  3. Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome. (PMID: 16273071) Washietl S … Stadler PF (Nature biotechnology 2005) 1

No data available for External Links for SNORA74C-1 Gene

Products for SNORA74C-1 Gene

Sources for SNORA74C-1 Gene

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