Subcategory (RNA class) for SNORA74C-1 Gene
Quality Score for this RNA gene is
Previous GeneCards Identifiers for SNORA74C-1 Gene
GeneCards Summary for SNORA74C-1 Gene
SNORA74C-1 (Small Nucleolar RNA, H/ACA Box 74C-1) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORA74C-1 Gene - the ORGUL cluster for this gene includes several descriptions:
nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.
Small nucleolar RNA SNORA74: U19 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs . Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing .