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Aliases for SNORA73A Gene

Subcategory (RNA class) for SNORA73A Gene


Quality Score for this RNA gene is


Aliases for SNORA73A Gene

  • Small Nucleolar RNA, H/ACA Box 73A 2 3 5
  • RNA, U17a Small Nucleolar 2 3
  • RNA, Small Nucleolar E1 3
  • RNU17A 3
  • E1-7 3
  • U17A 3
  • RNE1 3
  • E1B 3
  • E1 3

External Ids for SNORA73A Gene

Previous HGNC Symbols for SNORA73A Gene

  • RNE1
  • RNU17A

Previous GeneCards Identifiers for SNORA73A Gene

  • GC01P028706
  • GC01P028840
  • GC01P028842
  • GC01P027088
  • GC01P028846
  • GC01P028850
  • GC01P028851
  • GC01P028852
  • GC01P028853
  • GC01P028855
  • GC01P028864

Summaries for SNORA73A Gene

GeneCards Summary for SNORA73A Gene

SNORA73A (Small Nucleolar RNA, H/ACA Box 73A) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA73A Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA73 family: U17 (SNORA73A and SNORA73B) also known as E1 belongs to the H/ACA class of small nucleolar RNAs (snoRNAs). Vertebrate U17 is intron-encoded and ranges in length from 200-230 nucleotides, longer than most snoRNAs. It is one of the most abundant snoRNAs in human cells and is essential for the cleavage of pre-rRNA within the 5' external transcribed spacer (ETS) [1]. This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms [2].

View fRNAdb secondary structures for SNORA73A

Additional gene information for SNORA73A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA73A Gene

Genomics for SNORA73A Gene

GeneHancer (GH) Regulatory Elements for SNORA73A Gene

Promoters and enhancers for SNORA73A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I028504 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 +0.8 844 6.6 CLOCK MLX YBX1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 SNORA73B RCC1 SNORA73A SRSF4 GMEB1 TRNAU1AP SNHG12 PHACTR4 YTHDF2 SNHG3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA73A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA73A gene promoter:

Genomic Locations for SNORA73A Gene

Genomic Locations for SNORA73A Gene
207 bases
Plus strand

Genomic View for SNORA73A Gene

Genes around SNORA73A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA73A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA73A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA73A Gene

ORGUL Member Location for SNORA73A Gene

ORGUL Member Location for SNORA73A gene

Proteins for SNORA73A Gene

Post-translational modifications for SNORA73A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA73A Gene

Domains & Families for SNORA73A Gene

Gene Families for SNORA73A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA73A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA73A Gene

Function for SNORA73A Gene

Gene Ontology (GO) - Molecular Function for SNORA73A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 10757788
genes like me logo Genes that share ontologies with SNORA73A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA73A Gene

Localization for SNORA73A Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORA73A gene
Compartment Confidence
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for SNORA73A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 10757788
GO:0072588 box H/ACA RNP complex IDA 10757788
genes like me logo Genes that share ontologies with SNORA73A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SNORA73A Gene

Pathways & Interactions for SNORA73A Gene

SuperPathways for SNORA73A Gene

No Data Available

Interacting Proteins for SNORA73A Gene

Gene Ontology (GO) - Biological Process for SNORA73A Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA73A Gene

Drugs & Compounds for SNORA73A Gene

No Compound Related Data Available

Transcripts for SNORA73A Gene

fRNAdb Secondary structures for SNORA73A Gene

  • FR020095

mRNA/cDNA for SNORA73A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA73A Gene

No ASD Table

Relevant External Links for SNORA73A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA73A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA73A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA73A Gene:

genes like me logo Genes that share expression patterns with SNORA73A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA73A Gene

Orthologs for SNORA73A Gene

Evolution for SNORA73A Gene

Gene Tree for SNORA73A (if available)
Gene Tree for SNORA73A (if available)

No data available for Orthologs for SNORA73A Gene

Paralogs for SNORA73A Gene

No data available for Paralogs for SNORA73A Gene

Variants for SNORA73A Gene

Sequence variations from dbSNP and Humsavar for SNORA73A Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000718042 -- 28,505,896(+) G/T upstream_transcript_variant
rs1001089666 -- 28,506,792(+) G/A upstream_transcript_variant
rs1001381360 -- 28,505,722(+) A/T upstream_transcript_variant
rs1001696462 -- 28,506,016(+) A/G upstream_transcript_variant
rs1002146857 -- 28,505,788(+) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA73A Gene

Variant ID Type Subtype PubMed ID
esv2657760 CNV deletion 23128226
esv3559994 CNV deletion 23714750
esv3585585 CNV loss 21293372
nsv545916 CNV gain 21841781
nsv545919 CNV loss 21841781
nsv947421 CNV duplication 23825009

Additional Variant Information for SNORA73A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA73A Gene

Disorders for SNORA73A Gene

Additional Disease Information for SNORA73A

No disorders were found for SNORA73A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA73A Gene

Publications for SNORA73A Gene

  1. Small nucleolar RNAs encoded by introns of the human cell cycle regulatory gene RCC1. (PMID: 8335005) Kiss T … Filipowicz W (The EMBO journal 1993) 1 2 3 58
  2. Three small nucleolar RNAs of unique nucleotide sequences. (PMID: 8421699) Ruff EA … Eliceiri GL (Proceedings of the National Academy of Sciences of the United States of America 1993) 1 2 3 58
  3. In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs. (PMID: 10757788) Dragon F … Filipowicz W (Molecular and cellular biology 2000) 1 3 58
  4. Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA. (PMID: 8391637) Rimoldi OJ … Eliceiri GL (Molecular and cellular biology 1993) 1 3 58
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA73A Gene

Sources for SNORA73A Gene

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