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Aliases for SNORA71D Gene

Subcategory (RNA class) for SNORA71D Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORA71D Gene

  • Small Nucleolar RNA, H/ACA Box 71D 2 3 5
  • U71d 3

External Ids for SNORA71D Gene

ORGUL Members for SNORA71D Gene

Previous GeneCards Identifiers for SNORA71D Gene

  • GC20P036495
  • GC20M036504
  • GC20M037062
  • GC20M033797

Summaries for SNORA71D Gene

GeneCards Summary for SNORA71D Gene

SNORA71D (Small Nucleolar RNA, H/ACA Box 71D) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA71D Gene

  • Small nucleolar RNA SNORA71: The members of this family belong to the H/ACA class of snoRNAs which bind a number of proteins (including dyskerin, Gar1p and Nop10p) to form snoRNP complexes. This class of snoRNAs are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs [2]. This family includes U71 (SNORA71), ACA39 (SNORA39) and ACA60 (SNORA60) [1,3]. U71 and ACA60 are predicted to guide the pseudouridylation of U406 and U1004 in 18S rRNA respectively [4]. There is currently no target RNA identified for ACA39 [3].

Additional gene information for SNORA71D Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA71D Gene

Genomics for SNORA71D Gene

GeneHancer (GH) Regulatory Elements for SNORA71D Gene

Promoters and enhancers for SNORA71D Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J038433 Promoter/Enhancer 1.6 Ensembl ENCODE 650.7 -0.8 -819 2.9 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 SNHG17 GC20M038434 GC20M038437 SNORA71D ACTR5 RALGAPB ENSG00000224635 TTI1 SNORA71A SNHG11
GH20J038471 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 12 -38.6 -38648 2.5 PKNOX1 ARNT MLX ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 RALGAPB SNHG17 SNORA71A SNORA71C ENSG00000224635 SNORA60 SNHG11 ENSG00000201811 SNORA71D RPS3P2
GH20J038373 Enhancer 0.7 ENCODE 10.2 +60.4 60387 0.2 BCOR HDAC1 MEIS2 ZMYM3 NFXL1 ADNP SMARCA5 RXRA CEBPB CBFA2T3 ENSG00000224635 SNORA71A SNORA71B ENSG00000206249 SNORA71C SNHG17 SNORA71D ENSG00000201811 SNHG11 SNORA60
GH20J038572 Enhancer 0.4 ENCODE 9.9 -139.9 -139895 1.8 RCOR1 CHD2 SNHG17 SNORA71A SNORA71B SNHG11 SNORA60 SNORA71D ENSG00000201811 SNORA71C ENSG00000224635 ARHGAP40
GH20J038519 Enhancer 0.2 VISTA 10.8 -86.4 -86428 1.4 SNHG11 SNORA60 ENSG00000201811 SNHG17 SNORA71D SNORA71C MIR548O2 RPS3P2 RALGAPB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA71D on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA71D gene promoter:
  • POU3F2
  • GATA-1
  • Elk-1
  • GR
  • GR-alpha
  • GR-beta
  • HSF1short
  • HSF1 (long)

Genomic Locations for SNORA71D Gene

Genomic Locations for SNORA71D Gene
chr20:38,433,862-38,433,999
(GRCh38/hg38)
Size:
138 bases
Orientation:
Minus strand
chr20:37,062,505-37,062,642
(GRCh37/hg19)
Size:
138 bases
Orientation:
Minus strand

Genomic View for SNORA71D Gene

Genes around SNORA71D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA71D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA71D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA71D Gene

Proteins for SNORA71D Gene

Post-translational modifications for SNORA71D Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA71D Gene

Domains & Families for SNORA71D Gene

Gene Families for SNORA71D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA71D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA71D Gene

Function for SNORA71D Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA71D Gene

Localization for SNORA71D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA71D Gene

Pathways & Interactions for SNORA71D Gene

SuperPathways for SNORA71D Gene

No Data Available

Interacting Proteins for SNORA71D Gene

Gene Ontology (GO) - Biological Process for SNORA71D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA71D Gene

Drugs & Compounds for SNORA71D Gene

No Compound Related Data Available

Transcripts for SNORA71D Gene

mRNA/cDNA for SNORA71D Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Unigene Clusters for SNORA71D Gene

Small nucleolar RNA, H/ACA box 71D:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA71D Gene

No ASD Table

Relevant External Links for SNORA71D Gene

GeneLoc Exon Structure for
SNORA71D
ECgene alternative splicing isoforms for
SNORA71D

Expression for SNORA71D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA71D Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA71D Gene:

SNORA71D

SOURCE GeneReport for Unigene cluster for SNORA71D Gene:

Hs.653086
genes like me logo Genes that share expression patterns with SNORA71D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA71D Gene

Orthologs for SNORA71D Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA71D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA71 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA71 34
  • 88 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SNORA71 34
  • 85 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA71 34
  • 83 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA71 34
  • 81 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm25853 34
  • 73 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA71 34
  • 77 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA71 34
  • 76 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA71 34 34
  • 73 (a)
ManyToMany
Species where no ortholog for SNORA71D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA71D Gene

ENSEMBL:
Gene Tree for SNORA71D (if available)
TreeFam:
Gene Tree for SNORA71D (if available)

Paralogs for SNORA71D Gene

No data available for Paralogs for SNORA71D Gene

Variants for SNORA71D Gene

Sequence variations from dbSNP and Humsavar for SNORA71D Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000630605 -- 38,433,791(-) G/A downstream_transcript_variant
rs1002586134 -- 38,435,897(-) C/T upstream_transcript_variant
rs1002876426 -- 38,435,273(-) G/A upstream_transcript_variant
rs1003266389 -- 38,433,530(-) A/G downstream_transcript_variant
rs1004157737 -- 38,434,105(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA71D Gene

Variant ID Type Subtype PubMed ID
esv2758794 CNV gain 17122850
esv35121 CNV gain 17911159
nsv1058457 CNV loss 25217958
nsv1063495 CNV gain 25217958
nsv509769 CNV insertion 20534489
nsv817893 CNV gain 17921354

Additional Variant Information for SNORA71D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA71D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA71D Gene

Disorders for SNORA71D Gene

Additional Disease Information for SNORA71D

No disorders were found for SNORA71D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA71D Gene

Publications for SNORA71D Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 58
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA71D Gene

Sources for SNORA71D Gene

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