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Aliases for SNORA70B Gene

Subcategory (RNA class) for SNORA70B Gene


Quality Score for this RNA gene is


Aliases for SNORA70B Gene

  • Small Nucleolar RNA, H/ACA Box 70B 2 3 5
  • Small Nucleolar RNA, H/ACA Box 70B (Retrotransposed) 2

External Ids for SNORA70B Gene

ORGUL Members for SNORA70B Gene

Previous GeneCards Identifiers for SNORA70B Gene

  • GC02U901156
  • GC02M061501
  • GC02M061645

Summaries for SNORA70B Gene

GeneCards Summary for SNORA70B Gene

SNORA70B (Small Nucleolar RNA, H/ACA Box 70B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA70B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA70: snoRNA U70 seems to be exclusive to mammals and is a member of the H/ACA class of snoRNA which contain H (ANANNA) and ACA box motifs. H/ACA box snoRNAs are involved in the conversion of uridines to pseudouridines (5-ribosyluracil) a constituent of structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar) [1,2].

View fRNAdb secondary structures for SNORA70B

Additional gene information for SNORA70B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA70B Gene

Genomics for SNORA70B Gene

GeneHancer (GH) Regulatory Elements for SNORA70B Gene

Promoters and enhancers for SNORA70B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I061417 Enhancer 0.3 FANTOM5 550.8 -0.3 -310 0.1 ZNF316 ENSG00000234624 SNORA70B AHSA2P USP34
GH02I061477 Enhancer 0.4 UCNEbase 10.3 -60.7 -60691 0.3 ENSG00000234624 SNORA70B CCT4 COMMD1 PIR55828 LOC105377633 XPO1
GH02I061478 Enhancer 0.2 dbSUPER 10.9 -61.3 -61308 0.6 ENSG00000234624 SNORA70B CCT4 COMMD1 AHSA2P PIR55828 LOC105377633 XPO1
GH02I061468 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.2 -53.2 -53227 4.7 HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 USP34 LOC105377633 LOC339803 AHSA2P PAPOLG PEX13 PUS10 SNORA70B
GH02I061424 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 -8.4 -8445 2.3 CTCF SAP130 ARID4B ZNF384 EBF1 IRF4 ZNF48 RAD21 CHAMP1 GATAD1 AHSA2P LOC339803 USP34 CCT4 COMMD1 SNORA70B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA70B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA70B gene promoter:

Genomic Locations for SNORA70B Gene

Genomic Locations for SNORA70B Gene
135 bases
Minus strand

Genomic View for SNORA70B Gene

Genes around SNORA70B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA70B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA70B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA70B Gene

ORGUL Member Location for SNORA70B Gene

ORGUL Member Location for SNORA70B gene

Proteins for SNORA70B Gene

Post-translational modifications for SNORA70B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA70B Gene

Domains & Families for SNORA70B Gene

Gene Families for SNORA70B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA70B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA70B Gene

Function for SNORA70B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA70B Gene

Localization for SNORA70B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA70B Gene

Pathways & Interactions for SNORA70B Gene

SuperPathways for SNORA70B Gene

No Data Available

Interacting Proteins for SNORA70B Gene

Gene Ontology (GO) - Biological Process for SNORA70B Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA70B Gene

Drugs & Compounds for SNORA70B Gene

No Compound Related Data Available

Transcripts for SNORA70B Gene

fRNAdb Secondary structures for SNORA70B Gene

  • RF00156;SNORA70;DAAB010734333.1/305-390

mRNA/cDNA for SNORA70B Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA70B Gene

Small nucleolar RNA, H/ACA box 70B:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA70B Gene

No ASD Table

Relevant External Links for SNORA70B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA70B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA70B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA70B Gene:


SOURCE GeneReport for Unigene cluster for SNORA70B Gene:

genes like me logo Genes that share expression patterns with SNORA70B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA70B Gene

Orthologs for SNORA70B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA70B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA70 34
  • 99 (a)
(Canis familiaris)
Mammalia SNORA70 34
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA70 34
  • 71 (a)
(Mus musculus)
Mammalia Gm23902 34
  • 66 (a)
(Danio rerio)
Actinopterygii SNORA70 34
  • 65 (a)
Species where no ortholog for SNORA70B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA70B Gene

Gene Tree for SNORA70B (if available)
Gene Tree for SNORA70B (if available)

Paralogs for SNORA70B Gene

No data available for Paralogs for SNORA70B Gene

Variants for SNORA70B Gene

Sequence variations from dbSNP and Humsavar for SNORA70B Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000184757 -- 61,416,846(-) G/A downstream_transcript_variant
rs1001230128 -- 61,419,172(-) T/C upstream_transcript_variant
rs1001777853 -- 61,419,367(-) G/T upstream_transcript_variant
rs1002078971 -- 61,418,733(-) C/A upstream_transcript_variant
rs1002128166 -- 61,419,134(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA70B Gene

Variant ID Type Subtype PubMed ID
nsv1014905 CNV gain 25217958
nsv7313 OTHER inversion 18451855
nsv961408 CNV duplication 23825009

Additional Variant Information for SNORA70B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA70B Gene

Disorders for SNORA70B Gene

Additional Disease Information for SNORA70B

No disorders were found for SNORA70B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA70B Gene

Publications for SNORA70B Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  2. snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang JH … Qu LH (Nucleic acids research 2006) 3 58
  3. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. (PMID: 12007400) Kiss T (Cell 2002) 1
  4. Pseudouridine in RNA: what, where, how, and why. (PMID: 10902565) Charette M … Gray MW (IUBMB life 2000) 1

Products for SNORA70B Gene

Sources for SNORA70B Gene

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