SNORA57 Gene (RNA Gene)

Small Nucleolar RNA, H/ACA Box 57

GC11P062681
GIFtS:
15

Aliases for SNORA57 Gene

Subcategory (RNA class) for SNORA57 Gene

snoRNA

Quality Score for this RNA gene is

15

Aliases for SNORA57 Gene

  • Small Nucleolar RNA, H/ACA Box 57 2 3 5
  • SNORA57 2 176
  • RF00191 174
  • U99 3

External Ids for SNORA57 Gene

Previous GeneCards Identifiers for SNORA57 Gene

  • GC11U900715
  • GC11P062194
  • GC11P062432
  • GC11P058762
  • GC11P062666
  • GC11P062675
  • GC11P062679
  • GC11P062667
  • GC11P062669
  • GC11P062673

Summaries for SNORA57 Gene

GeneCards Summary for SNORA57 Gene

SNORA57 (Small Nucleolar RNA, H/ACA Box 57) is an RNA Gene, and is affiliated with the snoRNA class.

Rfam classification for SNORA57 Gene

  • Small nucleolar RNA SNORA57

Additional gene information for SNORA57 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA57 Gene

Genomics for SNORA57 Gene

GeneHancer (GH) Regulatory Elements for SNORA57 Gene

Promoters and enhancers for SNORA57 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH11J062664 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 +0.5 520 4.3 SIN3A SP1 ZBTB40 FOXA1 MLX RBPJ POLR2A NR2F6 CREB1 HCFC1 CSKMT C11orf98 ENSG00000255432 SNORA57 lnc-C11orf98-1 lnc-UQCC3-1 LBHD1 EML3 NXF1 GANAB
GH11J062712 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE dbSUPER 10.8 +48.7 48663 3.8 FOXA1 SP1 CBFA2T2 MLLT1 PRDM1 RXRA FOXA2 ZNF316 NR2C1 JUND piR-45619 HNRNPUL2 TTC9C UBXN1 LBHD1 LRRN4CL POLR2G GANAB B3GAT3 UQCC3
GH11J062694 Enhancer 0.9 Ensembl ENCODE 12 +29.4 29443 1.1 CTCF CC2D1A RAD21 EGR1 ARID2 REST BACH1 TRIM22 ZNF143 ZNF561 BSCL2 TTC9C LBHD1 SNORA57 CSKMT ENSG00000255432 INTS5 GANAB UQCC3 EML3
GH11J062637 Enhancer 0.3 ENCODE 11.4 -26.8 -26751 2.6 ZNF366 lnc-ROM1-5 EML3 LBHD1 UQCC3 ENSG00000255432 SNORA57 CSKMT ENSG00000254964 MTA2 ENSG00000255508
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA57 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA57 gene promoter:
  • AP-4
  • C/EBPalpha
  • LUN-1
  • Max1
  • NF-1
  • POU6F1 (c2)
  • PPAR-alpha
  • RORalpha1
  • Sp1
  • TBP

Genomic Locations for SNORA57 Gene

Genomic Locations for SNORA57 Gene
chr11:62,665,422-62,665,570
(GRCh38/hg38)
Size:
149 bases
Orientation:
Plus strand
chr11:62,432,894-62,433,042
(GRCh37/hg19)
Size:
149 bases
Orientation:
Plus strand

Genomic View for SNORA57 Gene

Genes around SNORA57 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA57 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA57 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORA57 Gene

Proteins for SNORA57 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORA57 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA57 Gene

Domains & Families for SNORA57 Gene

Gene Families for SNORA57 Gene

HGNC:
genes like me logo Genes that share domains with SNORA57: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORA57 Gene

Function for SNORA57 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for SNORA57 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA57 Gene

Localization for SNORA57 Gene

Gene Ontology (GO) - Cellular Components for SNORA57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA57: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORA57 Gene

Pathways & Interactions for SNORA57 Gene

PathCards logo

SuperPathways for SNORA57 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORA57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA57: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA57 Gene

Drugs & Compounds for SNORA57 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for SNORA57 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for SNORA57 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNACentral transcripts :
(1) ENA transcripts :
(1) Rfam transcripts :
(1) snOPY transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA57 Gene

No ASD Table

Relevant External Links for SNORA57 Gene

GeneLoc Exon Structure for
SNORA57
ECgene alternative splicing isoforms for
SNORA57

Expression for SNORA57 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA57 Gene

mRNA expression in normal human tissues for SNORA57 Gene
mRNA expression by GTEx for SNORA57 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA57 Gene:

SNORA57

SOURCE GeneReport for Unigene cluster for SNORA57 Gene:

Hs.687390
genes like me logo Genes that share expression patterns with SNORA57: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA57 Gene

Orthologs for SNORA57 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA57 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia SNORA57 33
  • 99 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Gm25822 33
  • 89 (a)
 OneToMany
Gm26132 33
  • 85 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia SNORA57 33
  • 80 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia SNORA57 33 33
  • 80 (a)
 ManyToMany
cow
(Bos Taurus)
 Mammalia SNORA57 33
  • 80 (a)
 ManyToMany
lizard
(Anolis carolinensis)
 Reptilia SNORA57 33
  • 73 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii SNORA57 33 33 33
  • 66 (a)
 ManyToMany
Species where no ortholog for SNORA57 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA57 Gene

ENSEMBL:
Gene Tree for SNORA57 (if available)
TreeFam:
Gene Tree for SNORA57 (if available)

Paralogs for SNORA57 Gene

No data available for Paralogs for SNORA57 Gene

Variants for SNORA57 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for SNORA57 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1003009191 -- 62,665,794(+) C/T downstream_transcript_variant
rs1003195972 -- 62,664,525(+) T/C upstream_transcript_variant
rs1003659267 -- 62,664,236(+) T/C upstream_transcript_variant
rs1005510640 -- 62,663,454(+) C/T upstream_transcript_variant
rs1007577564 -- 62,665,300(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA57 Gene

Variant ID Type Subtype PubMed ID
nsv555174 CNV gain 21841781
nsv832182 CNV gain+loss 17160897

Additional Variant Information for SNORA57 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA57

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA57 Gene

Disorders for SNORA57 Gene

Additional Disease Information for SNORA57

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for SNORA57 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA57 Gene

Publications for SNORA57 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 56
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 56
  3. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 56
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 56
  5. Identification of 13 novel human modification guide RNAs. (PMID: 14602913) Vitali P … Cavaillé J (Nucleic acids research 2003) 3 56

ExternalLinks

View latest publications for SNORA57 gene in Mastermind

Products for SNORA57 Gene

Sources for SNORA57 Gene